Nick Gracey WATerian BSc(Hons) Medical BioChemistry, Birmingham University, Adrenaline LIFE2345.©OM: WATerian ... REFERENCES...

"Every Day And In Every Way I Am Getting Better And Better"...
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Eating less OFTEN is profoundly more healthy than eating less...

> 0400 www.tinyurl.cOM/2j7p3t [DFadool@neuro.fsu.edu]
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www.DiabetesHealth.cOM/read/2007/12/19/5575.html
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http://%3ca%20href=/
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> 0108 www.tinyurl.cOM/2thsjo {JCVoltar@fmrp.usp.br ~ J.C. Voltarelli @ Universidade de São Paulo, Ribeirão Preto, SP, Brasil ... '...T1 diabetes is associated with the autoimmune 'reduction' of the insulin-producing pancreatic Beta-Cells. This autoimmune 'Beta-Cell DOWN-REGULATION' may begin days, weeks, months or even years BEFORE the presentation of HYPERglycemia symptoms. At the time of clinical diagnosis, 'often' less than 30% of Beta-Cell mass still remains. The conventional therapeutic option to T1D is daily insulin injections ... Diabetics with less HYPOglycemia events sustained higher serum levels of C-peptide and suffered less micro-vascular complications over the subsequent years ... In face of this, preservation/up-regulation [www.tinyurl.cOM/2j5hmm] of Beta-Cell insulin production & Beta-Cell C-peptide production is an important target in the management of T1D and its related complications ?...'}
> 1207 www.tinyurl.com/2k6979 [BetterCell.blogspot.com]
> 1207 www.tinyurl.cOM/ys7vkw {Matthias@liai.org ~ Matthias von Herrath @ La Jolla Institute for Allergy and Immunology, California 92037, USA ... '...T1 diabetes is a relapsing/remitting/REVERSIBLE disease ?...'}
> 1207 www.tinyurl.com/27pwj8 [saskiananette@hotmail.com]
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Beta-cells continue healthy function even at 30 mmol/l or 540 mg/dL
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Douglas Kamerow, US editor of BMJ: Is everything you know wrong?
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www.TheDiabetesBlog.cOM/2007/05/25/tv-causes-elevated-glucose-in-children
www.TheDiabetesBlog.com/2007/04/19/no-food-no-problem
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www.DiabetesHealth.com/read/2007/04/11/5113.html
www.TheDiabetesBlog.com/2007/04/03/the-honeymoon-period
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> 0107 www.tinyurl.com/2eyxy3 [John.Wahren@ki.se]
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> 1006 www.tinyurl.cOM/yu4695 {JCVoltar@fmrp.usp.br ~ J.C. Voltarelli @ Universidade de São Paulo, Brasil ... '...Secondary PREVENTION of T1 diabetes: reducing autoimmune 'Beta-Cell down-regulation' and promoting Beta-Cell Insulin "BCI" production & Beta-Cell C-peptide "BCC" production ?...'}
> 0806 www.tinyurl.com/23x2nv [vbhatia@sgpgi.ac.in]
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> 0999 http://www.ncbi.nlm.nih.gov/pubmed/10500933 {Redmo001@maroon.tc.umn.edu ~ J.B. Redmon @ University of Minnesota Medical School, Minneapolis, USA ... "...Autoimmune HYPOglycemia}
> 0597 www.tinyurl.com/yr8b95 [Katrina Leskanich]
www.DiabetesHealth.cOM/read/1995/05/01/350.html
> 0192 www.tinyurl.cOM/2vp36k {Robert.Cohen@uc.edu @ University of Cincinnati Medical Center, Ohio, USA ... '...HYPOglycemia with HYPERinsulinemia ... following CALCITRIOL [www.tinyurl.cOM/2hpzxp] = VITAMIN 'D' [a steroid hormone precursor] which is associated with inducing HYPOglycemia [and associated down-regulation of insulin gene expression (http://www.tinyurl.com/2cgavg%29] and CALCITRIOL aka 'Vitamin Diabetes' may induce Relative-HYPOglycemia-Distress (RHOD) by masking protective HYPERglycemia and may also, in some countries, lead to reductions in diagnosis of T1D and an associated increased incidence of Neuro-Psychiatric-Illness [http://www.relative-hypoglycemia.com/] ?...'}
> 0183 www.tinyurl.com/329umr [Hans.Lithell@pubcare.uu.se]
> 0180 www.tinyurl.com/3xtff9 {T Deckert ~ Good guidance of T1A = more natural BCI & BCC-peptide SECRETION}
> Rosenbloom, AL, Giordano, BP: Chronic over-treatment with insulin in children and adolescents. Am J Dis Child 131: 881-885, 1977.
> 0367 www.tinyurl.com/2uxb99 [Dr Allan Cott]
> Somogyi, M: Exacerbation of diabetes by excess insulin action. Am J Med, 26: 169-191, 1959.
> Somogyi, M, Kirstein, M: Insulin as a cause of extreme hyperglycemia and instability. Week Bull St Louis M Soc 32: 498, 1938.

> www.en.wikipedia.org/wiki/Acidosis
> www.en.wikipedia.org/wiki/Amyloid
> www.en.wikipedia.org/wiki/Amyloid_beta
> www.en.wikipedia.org/wiki/Coeliac_disease

Posted by Nicholas Dynes Gracey on 29 November 2007

Hi Robert Tanenberg & the Editorial Team,

1. You say: "insulin travels to the liver or muscles" ...
... Without any mention of fat cells OR mentioning that blood glucose feeds the brain efficiently in the absence of insulin ... Why your ZERO mention of fat cells(?). Insulin receptors on fat cells are [and always have been] extra-ordinarily important in the science of insulin function and are the main reason WHY: (a) excess insulin ['the fat storage hormone'] helps make People obese; and (b) excess insulin ['HYPERinsulinemia'] can send People into HYPOglycemic shock [because excess insulin causes blood glucose to be shunted-off into the FAT cells thereby starving the brain of a previously available circulation of blood glucose] aka 'relative-HYPOglycemia' ...

WHY have fat insulin receptors been so questionably ignored by your "Insulin For Type 2 Diabetes: Who, When, And Why?" article?

2. You say: "When fasting glucose tops 125 mg/dl, a patient is considered to have diabetes. It has been shown that when persons are first diagnosed with type 2 diabetes, they have already lost over fifty percent of their beta-cell function" ...
... Now your article is without ANY mention of how often 'beta-cell function' is EVER actually medically tested for when 'a type 1 OR type 2 Patient is first considered to have diabetes' OR without any explanation as to why a Person is questionably diagnosed with "Diabetes Mellitus" [glucose in urine] when even short-term fasting returns such a Patient's blood glucose to 'well-less' than 180 mg/dl [ie the average urinating threshold] ...

WHO wrote the Peer-reviewed references to describe, quantify & evidence the alleged '50% loss of beta-cell function' ?

3. You say: "Unfortunately, many people with type 2 diabetes experience progressive loss of beta cell function. Their overworked beta cells seem to burn out" ...
... 'seem to burn out' ?? How scientific is that statement(?). Following your article & some 70 years of treating type 2 Diabetic People, having above average blood glucose [aka 'HYPERglycemia'], with some type of 'HYPOglycemic drug' / 'anti-Diabetic drug' [http://en.wikipedia.org/wiki/Anti-diabetic_drug] ... it is reasonable to expect your clear & prompt answer to the following 2 questions ...

(a) WHEN was the scientific evidence first provided documenting the CAUSE associated with your allegation of 'burn-out' of beta-cells?; and
(b) WHEN has any reference, with an UNdrugTREATED control [ie comparing a Diabetic Group entirely UNdrugTREATED], ever been produced, that has ever evidenced that type 2 Diabetics are less healthy UNdrugTREATED as compared with ANYdrugTREATED [eg genetically modified (GM) insulin]??

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 13:32hrs THU.29.NOV.2007.

http://www.diabeteshealth.com/read/2007/12/03/5558.html

Posted by Nicholas Dynes Gracey on 29 November 2007

Hi Robert Tanenberg, Anonymous & AnyOne else,

Anonymous, You say: "I am constantly running close to 180, which isn't good." ...
... You appear to have a belief that 180 mg/dl is other than healthy for an UNdrugTREATED Diabetic.

PLEASE identify [or have your GP or diabetes Nurse or diabetes clinic identify] ANY Peer-reviewed scientific reference, with an UNdrugTREATED control [ie comparing a Diabetic Group entirely UNdrugTREATED], ever been produced, that has ever evidenced that type 2 Diabetics are less healthy UNdrugTREATED ??

What if there is ZERO reference anywhere in the history of the world that provides Peer-reviewed evidence that ANYdrugTREATED is better than UNdrugTREATED for all type 2 Diabetics?

Please AnyOne identify just 1 such reference.

In the continued absence of any such reference it it reasonable to suppose that every type 2 Diabetic 'complication' arises as a result of the treatment of the 'insulin resistance' that was actually keeping type 2 Diabetics healthy in the first place.

Presumably, in respect of 'Who is ultimately responsible for any consequential side-effects?' ... such a reference should be producible by a GP or an MD or any other prescribing Physician treating their type 2 Diabetic Patient...

The Hippocratic Oath states: "To please no one will I prescribe a deadly drug nor give advice which may cause his death." ...

www.tinyurl.com/34lyyj

BMJ 1997;315:1105-1106 (1 November)
Editorials

'... Why some cases of retinopathy worsen when diabetic control improves ... the rate of fall of blood glucose concentration and the accompanying reduction in blood flow have been thought to be the trigger ... This suggestion was supported by the finding of Grunwald et al, who showed a 20% reduction of blood flow when blood glucose concentrations fell from about 15 mmol/l to 8 mmol/l.'

As compared with the relative HIGH / JOY of UNdrugTREATED type 2 diabetes…

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 15:50hrs THU.29.NOV.2007.

http://www.diabeteshealth.com/read/2007/12/03/5558.html

Posted by AllieB2 on 29 November 2007

Most people with Type 2 are consuming 3x the amount of carbohydrates their body can handle.

When doctors prescribe insulin to override this force of nature -- the body says PLEASE EAT LESS!! By putting more insulin into the body (artificial insulin) it causes clots and other damage to the systems (circulatory, mostly -- heart and brain).

When doctors prescribe oral agents to slow the release of glycogen from the liver -- this causes the LIVEr to become diseased -- which also leads to complications in Type 2 diabetes. Every ORAL medication lists side effects alluding to symptoms of developing a FATTY LIVER, as well as heart and kidney problems.

Why do people trust these drug pushers? I know of very few people with Type 2 diabetes that die of natural causes.

I welcome anybody to argue or support such evidence. Please contact me on TuDiabetes.com - A Community for People Touched by Diabetes. Many people with Type 1 and Type 2 have a lot of great advice to share on how to weather the squalls in hurricane diabetes.

Best,
Allie

Allison Love Beatty - Founder of "Allies Voice"
Making the World Safer for People with Diabetes
http://www.alliesvoice.com/

Posted by Nicholas Dynes Gracey on 29 November 2007

Hi Robert Tanenberg, Anonymous, AllieB2 & AnyOne else,

AllieB2, You say: "Most people with Type 2 are consuming 3x the amount of carbohydrates their body can handle." ...

How do You know ?

There is ZERO requirement for any carbohydrate by Human Beings.

UNdrugTREATED type 2 Diabetics can handle plenty of carbohydrate ... They need to drink more water because they 'handle' excess carbohydrate simply by urinating excess glucose [water-soluble] just like People urinate excess water-soluble vitamins.

UNdrugTREATED type 1 Diabetics can handle relatively little carbohydrate ... They need to drink even more water because they 'handle' virtually all excess carbohydrate by urinating it just like People urinate excess water-soluble vitamins.

Both UNdrugTREATED type 1 & 2 Diabetics should test daily with ChemStrips and pause from eating, and drink just water, until their urine is glucose free. The less carbohydrate eaten ... the less time between meals.

That is how to CURE type 1 & type 2 Diabetes.

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 18:33hrs THU.29.NOV.2007.

http://www.diabeteshealth.com/read/2007/12/03/5558.html

Posted by anonymous on 29 November 2007

I'm a type-2 who recently started once-a-day insulin, using the Pen. My prior (and unfounded) insulin phobia were related to concerns about injection risks (not pain) and and calculating insulin dosing. I thought that injections had to go into particular places because vaccines go into muscle and some drugs go into veins. That made me wonder if I could be careful enough to inject myself into the right tissue and hit or avoid blood vessles and not inject air, causing an embolism? The answer I found was that the needle on the pen is short enough to avoid the wrong tissue and my injection site solves the other issues. The tummy for example, doesn't seem to have as many nerve endings as some other places, so combined with the thin needle it almost can't be felt. As to dosing, one can start with a base dosage of slow-acting and up it or lower it based on BG reading.

The one issue I'm still working on is matching my dose to my BG reading and "getting my number down". ;-)

I'd recommend to all doctors that when they first tell a patient that they have diabetes, they should immediately expose them to BG meters and Insulin injections by making the patient use both tools for themselves (with 31/33 guage lancets and needles), even if they may be able to avoid insulin or testing. They will lose their concerns and get a glimpse of one treatment they can work to avoid or postpone.

Posted by ricklude on 29 November 2007

HUH?

Allie. What are you trying to say? That, a controled diet & excersize ALONE will do the job. . .for EVERYONE?

I wish this were true in my case.

I tried that route years ago, counting every single carb, putting myself on, what my dietician said, was a "starvation diet" of 1500 cal. daily and excersizing in addition to the physical labor required of my profession.

For four months I did this when diagnosed and my BG meter sometimes could not display a number becouse it was so high! {But, I did loose alot of fatty weight and thined up which, isn't a bad thing for a "husky" diabetic guy.}

Only with the addition of oral meds and a normal diet, did my numbers come down to normal ranges and a few months ago, when they started an upward swing again, I started taking a long acting insulin which is working great.

So much for your big bad drug companies and their "pushed" medications theory. Not every diabetic responds the same way to ANY form of treatment(s).

I will, at least, check out your sites you've posted. Perhaps there is something I could learn within them.

Posted by ricklude on 29 November 2007

Nick.
Ahhhhhh. Yeah.

Posted by Nicholas Dynes Gracey on 29 November 2007

Hi Robert Tanenberg, Anonymous, AllieB2, ricklude & AnyOne else,

ricklude, You say: "my dietician said..."

How do You know that, what was said, was true ?

... You appear to have a belief that above average blood glucose is other than healthy for an UNdrugTREATED Diabetic who drinks plenty of water.

PLEASE identify [or have your MD or Dietician or diabetes Nurse or diabetes clinic identify] ANY Peer-reviewed scientific reference, with an UNdrugTREATED control [ie comparing a Diabetic Group entirely UNdrugTREATED], ever been produced, that has ever EVIDENCED that type 2 Diabetics [cats/dogs/mice/People/rats etc with above average blood glucose] are less healthy UNdrugTREATED ??

ricklude, then You say: "Ahhhhhh. Yeah."

All jokes are negative.

Diabetes Is Caused By Food And Or Drug Administration Too Much And Or Too Often.

Eating less is profoundly different from eating less OFTEN.

There really is ZERO requirement for any carbohydrate by Human Beings.

UNdrugTREATED type 2 Diabetics can handle plenty of carbohydrate ... They need to drink more water because they 'handle' excess carbohydrate simply by urinating excess glucose [water-soluble] just like People urinate excess water-soluble vitamins.

UNdrugTREATED type 2 Diabetics and other healthy People should test daily with ChemStrips and pause from eating, and drink just water, until their urine is glucose free. The less carbohydrate eaten ... the less time between meals.

That is how to CURE type 2 diabetes and prevent all 'newly diagnosed' type 1 & type 2 diabetes.

Eating less is profoundly different from eating less OFTEN.

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 19:32hrs THU.29.NOV.2007.

http://www.diabeteshealth.com/read/2007/12/03/5558.html

Posted by anonymous on 29 November 2007

Good article. I was diagnosed type 2 in March 07. I'm 36, 5'11" and weight 205 lbs.

Learning that my beta cells are already half-dead is sobering and depressing.

I'd like to avoid insulin as much as possible. My last A1C was 6%. Hopefully in "15 years" better treatments will be available so I can remain off of insulin.

Posted by anonymous on 29 November 2007

Why are you still pushing Avandia. It is a high risk drug

Posted by anonymous on 29 November 2007

Hi Nicholas,
Can you elaborate on your statement about insulin resistance? "In the continued absence of any such reference it it reasonable to suppose that every type 2 Diabetic 'complication' arises as a result of the treatment of the 'insulin resistance' that was actually keeping type 2 Diabetics healthy in the first place."
This is the first time I have heard that insulin resistance can keep a person healthy. I've only heard that insulin resistance is bad.

Posted by anonymous on 29 November 2007

The latest research shows that type 2 diabetes is caused by inflammation and not obesity. Exercise and fish oil reduce inflammation. What else can be done to reduce inflammation so that diabetes can be reversed. Why continue to treat the "symptoms" of diabetes with drugs instead of getting to the root cause. What causes inflammation?

Posted by Nicholas Dynes Gracey on 30 November 2007

Hi Robert Tanenberg, anonymous, AllieB2, ricklude & AnyOne else,

Robert Tanenberg says: "When fasting glucose tops 125 mg/dl, a patient is considered to have diabetes. It has been shown that when persons are first diagnosed with type 2 diabetes, they have already lost over fifty percent of their beta-cell function" ...
... Now Robert Tanenberg's article is without ANY mention of how often 'beta-cell function' is EVER actually medically tested for when 'a type 1 OR type 2 Patient is first considered to have diabetes' OR without any explanation as to why a Person is questionably diagnosed with "Diabetes Mellitus" [glucose in urine] when even short-term fasting returns such a Patient's blood glucose to 'well-less' than 180 mg/dl [ie the average urinating threshold] ...

WHO wrote the Peer-reviewed references to describe, quantify & evidence the alleged '50% loss of beta-cell function' ?

anonymous, You say: "Learning that my beta cells are already half-dead is sobering and depressing."

How do You know that, what was said, was true ?

(1) What test was done to quantify your 'beta-cell function' at the time of your first being diagnosed with type 2 diabetes?

(2) What test was done to quantify your 'beta-cell function' at the time of your most recent medical to check-up to calculate if You still qualify for a type 2 diabetes diagnosis?

Please compare (1) with (2) and work-out, for Yourself, how your beta-cell function has improved or otherwise.

(3) What is your expectation for your year-on-year improvement, in your beta-cell function, under your current medical treatment?

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 18:17hrs FRI.30.NOV.2007.

http://www.diabeteshealth.com/read/2007/12/03/5558.html

http://www.healself.org/Diabetes.html

Posted by Nicholas Dynes Gracey on 30 November 2007

Hi Robert Tanenberg, anonymous, AllieB2, ricklude & AnyOne else,

anonymous You say: "It is a high risk drug."
... You appear to have a belief [founded upon what evidence(?)] that some risk should be associated & calculated into the prescribing / taking of some drug to treat a type 2 Diabetic ... ie a Person who appears to have an above average blood glucose measurement.

PLEASE identify [or have your MD or diabetes Nurse or diabetes clinic identify] ANY Peer-reviewed scientific reference, with an UNdrugTREATED control [ie comparing a Diabetic Group entirely UNdrugTREATED], ever published, that has ever evidenced that type 2 Diabetics [who are capable of drinking plenty of clean water] are less healthy UNdrugTREATED ?

What if there is ZERO reference anywhere [since the discovery of type 2 diabetes] that provides Peer-reviewed evidence that: 'type 2 Diabetics being ANYdrugTREATED' is allegedly better than 'type 2 Diabetics being UNdrugTREATED' ??

Please anonymous, or AnyOne else, identify just 1 such reference that JUSTIFIES a type 2 Diabetic [who is capable of drinking plenty of clean water] being ANYdrugTREATED ???

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 18:40hrs FRI.30.NOV.2007.

http://www.DiabetesHealth.com/read/2007/12/03/5558.html

http://www.HealSelf.org/Diabetes.html

Posted by Nicholas Dynes Gracey on 30 November 2007

Hi Robert Tanenberg, anonymous, AllieB2, ricklude & AnyOne else,

anonymous You say: "I've only heard that insulin resistance is bad."
... You appear to have a belief [founded upon what evidence(?)] that some risk should be associated with glucose / insulin resistance.

PLEASE identify [or have your MD or diabetes Nurse or diabetes clinic identify] ANY Peer-reviewed scientific reference, with an UNdrugTREATED control [ie comparing a Diabetic Group entirely UNdrugTREATED], ever published, that has ever evidenced [for Diabetics who are capable of drinking plenty of clean water] that glucose / insulin resistance is other than healthy ?

What if there is ZERO reference anywhere [since the discovery of diabetes] that provides Peer-reviewed evidence that: 'insulin resistance is other than healthy' for ANY living cells [cats/dogs/mice/People/rats/worms etc] with above average blood glucose ??

Here is an example of the sort of reference that provides EVIDENCE that insulin resistance is beneficial ...
http://www.tinyurl.com/3aypqg

HYPOgycemia / relative-HYPOglycemia is ... more likely to happen ... the less the glucose / insulin resistance ...

BECAUSE

Diabetics are more protected from sudden HYPOgycemia c/o more glucose / insulin resistance ie leaving more glucose in a Diabetic's blood circulation [for feeding brain / optic / nerve cells] rather than glucose being too rapidly shunted-off [eg by GM insulin] into fat / liver / muscle cells ... TOO easily ... when glucose / insulin resistance [eg via insulin fat receptors / insulin liver receptors / insulin muscle receptors] is too LOW.

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 19:33hrs FRI.30.NOV.2007.

http://www.DiabetesHealth.com/read/2007/12/03/5558.html

http://www.HealSelf.org/Diabetes.html

http://www.tinyurl.com/34lyyj

Posted by anonymous on 30 November 2007

Regarding insulin resistance:
I had a GTT test 30 years ago when I was in my 20's because I complained of hypoglycemia. My blood sugar went from 80 at fasting to 200 and then dropped to 40. The doctor told me that when I got older I would gain weight and develop diabetes, which is exactly what happened. I was lean and fit, and now I am fat and diabetic. I control my diabetes with low carbs and exercise, but my body will not lose weight. I have always been insulin resistant, even when I was a lean athlete. I had problems with hypoglycemia, so it makes sense that insulin resistance is a protective mechanism for hypoglycemia.

Posted by Nicholas Dynes Gracey on 30 November 2007

Hi Robert Tanenberg, anonymous, AllieB2, ricklude & AnyOne else,

anonymous You say: "What causes inflammation?"
... Evidence for the removal of inflammation providing a very rapid CURE for both type 2 & type 1 Diabetics is here ...
http://www.tinyurl.com/y7znor

The answer to your question is a follows ...

Inflammation Is Caused By Food And Or Drug Administration Too Much And Or Too Often.

For example cooked food generally causes more inflammation than raw food by means of a digestive process called "leukocytosis".

Another word that can usefully help describe inflammation is "indigestion".

Indigestion Is Caused By Food And Or Drug Administration Too Much And Or Too Often.

Inflammation / Indigestion is caused by cellular over-load ... which occurs at different times in different People depending upon their 'powers of digestion' at any given time.

Eating less often can CURE both indigestion & inflammation.

Eating less is profoundly different from eating less OFTEN.

HYPERglycemia aka excess blood glucose aka excess blood carbohydrate ... is a symptom of indigestion / inflammation.

There is ZERO requirement for any carbohydrate by Human Beings.

UNdrugTREATED type 2 Diabetics can handle plenty of carbohydrate ... They need to drink more water because they 'handle' excess carbohydrate simply by urinating excess glucose [water-soluble] just like People urinate excess water-soluble vitamins.

UNdrugTREATED type 2 Diabetics and other healthy People should test daily with ChemStrips and pause from eating, and drink just water, until their urine is glucose free. The less carbohydrate eaten ... the less time between meals.

That is how to CURE type 2 diabetes and prevent all 'newly diagnosed' type 1 & type 2 diabetes.

Eating less is profoundly different from eating less OFTEN.

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 20:14hrs FRI.30.NOV.2007.

http://www.DiabetesHealth.com/read/2007/12/03/5558.html
http://www.HealSelf.org/Diabetes.html
http://www.tinyurl.com/34lyyj
http://www.tinyurl.com/y7znor

Posted by anonymous on 30 November 2007

A question for Nick:
If insulin resistance protects against hypoglycemia, and therefore drugs that increase insulin sensitivity are defeating the protective purpose of insulin resistance, as you stated, "Diabetics are more protected from sudden HYPOgycemia c/o more glucose / insulin resistance ie leaving more glucose in a Diabetic's blood circulation [for feeding brain / optic / nerve cells] rather than glucose being too rapidly shunted-off [eg by GM insulin] into fat / liver / muscle cells ..." Then is exercise counterproductive? When I exercise, my blood sugar plunges, sometimes down to 50. I am type 2 diabetic and control my blood sugar by diet and exercise alone. Apparently, I am under the misunderstanding that low blood sugar is better than high, and since I do not take any insulin or medication, I don't worry about hypoglycemia. Should I worry? Should I increase my carbs to treat/prevent hypoglycemia during exercise? If, as you say, there is zero requirements for carbs, how do I prevent hypoglycemia without eating more carbs?

Posted by bird54 on 1 December 2007

Hi Dr. Tanenberg,
You said, "Insulin resistance typically precedes outright diabetes by several years, appearing in adults and children who are overweight, sedentary, and have a genetic predisposition to diabetes."
However, some people who are sedentary and obese never develop diabetes and others who are lean and physically active do develop diabetes. There must be a reason for "insulin resistance" if so many people have it. Taking drugs to make the body more insulin sensitive, and adding more insulin to someone who already has too much, seems to be assaulting our bodies, like force feeding someone who is already full and is screaming, "No more!" Why is there a diabetes epidemic anyway? Why won't anyone get to the root cause?

Posted by bird54 on 1 December 2007

Hi Dr. Tenenberg,
Regarding your statement, "When the pancreatic beta cells can no longer overcome the insulin resistance, blood sugars begin to rise. Initially, only the post-meal glucose values are elevated, but in time the fasting glucose levels also increase. When fasting glucose tops 125 mg/dl, a patient is considered to have diabetes."
That is exactly what happened to me. I was insulin resistant at age 23, my postpranial glucose at a diabetic level, even though I was very lean and physically fit. Later I developed gestational diabetes but returned to normal after delivery. Years later, my fasting blood sugar went to 150 and my Aic was 7.6%. I am no longer diabetic. My A1c is down to 5.9%. This mornning, my fasting BS was 84. I am improving, not getting progressively worse. When I get lots of sleep, exercise, and eat low carbs, my diabetes disappears. Sleep seems to be the main factor, because when I am sleep deprived, my fasting blood sugar continues to rise regardless of exercise and diet. I wonder if the diabetes epidemic is caused by people being stressed by overwork and sleep deprivation.

Posted by Nicholas Dynes Gracey on 2 December 2007

Hi Robert Tanenberg, anonymous, AllieB2, ricklude, bird54 & AnyOne else interested in my opinion [following more than 27 years of diabetes-associated research] ...

bird54 You say: "There must be a reason for "insulin resistance" if so many people have it."
... Insulin resistance can also be usefully termed "GLUCOSE-RESISTANCE" because fat / liver / muscle cells, with insulin receptors, become more 'resistant' to glucose entry into those cells c/o protective adaptative changes in the insulin fat receptors / insulin liver receptors / insulin muscle receptors.

The reason for & the body's adjustment of its ... glucose / insulin resistance ... is determined by the brain's requirement for glucose. The more DISTRESSED a Person is the greater the nervous system's demands for glucose and the greater the likely-hood of relative-HYPOglycemia and/or absolute-HYPOglycemia ... IF ... there is a short-fall in glucose availability relative to the distressed brain / nervous system's increased requirement for glucose.

Diabetes aka "above average blood glucose concentration" aka "HYPERglycemia" can be viewed as a 'protective state' during times of "DISTRESS".

Please read the following referenced evidence associated with increased glucose / insulin resistance [& associated increased 'protective' HYPERglycemia] during the relative DISTRESS [lack of control] of watching television (TV) as compared to the relative 'joy of STRESS' [within control] when interacting with a personal computer (PC)...
http://www.tinyurl.com/2opc5h

Diabetics [People 'DIAgNOSED' with above average blood glucose concentrations] are more PROTECTED from sudden HYPOglycemia c/o more glucose / insulin resistance ie leaving more glucose available in a Diabetic's blood circulation [for feeding brain / optic / nerve cells] rather than glucose being too rapidly shunted-off [eg by HYPOglycemic drugs] into fat / liver / muscle cells ... TOO easily ... when glucose / insulin resistance [eg via insulin fat receptors / insulin liver receptors / insulin muscle receptors] is too LOW.

"People" includes Babies, Children, Adolescents, Athletes, Body-builders, Pensioners, Elderly, Patients & pregnant (gestating) Women...

Cats/dogs/mice/People/rats/worms etc ... who are sedentary, obese & sleep well are less likely to develop "above average blood glucose concentrations" than lean, physically active & sleep-deprived ... DISTRESSED cats/dogs/mice/People/rats/worms etc.

Diabetes is NOT a disease … diabetes is the CURE [for relative-HYPOglycemia].

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 10:17hrs SUN.02.DEC.2007.

www.DiabetesHealth.com/read/2007/12/03/5558.html
http://www.HealSelf.org/Diabetes.html
http://www.tinyurl.com/34lyyj
http://www.tinyurl.com/y7znor
http://www.tinyurl.com/2opc5h

Posted by bird54 on 2 December 2007

Thanks Nick!
Perhaps many people with diabetes get progressively worse because they work too hard at trying to control their blood sugar (by way of starvation diets and strenuous exercise) rather than getting adequate sleep and relaxation. I feel much better after a relaxing walk and a good night's sleep. I can even eat more carbs if I take a 20 minute walk after meals.

Posted by anonymous on 2 December 2007

I was Diagnosed Type 2 since 1984, my A1c is at 7 since last year 2006. I found by my own "common sense" 2 Years ago that "Exercise" AFTER meals for 20-30 minutes "LOWERED" my sugar back to 80-100 range! For "YEARS" I WASNOT Exercising AFTER meals: just taking oral meds plus Metformin LIKE MOST Diabetics I have met in my life! Now that my A1c is at 7; I will start some type of insulin because by my own reading diabetic news articles over the years I DIDN'T KNOW I WOULD SOMEDAY HAVE TO START INSULIN! My Doctors "NEVER" mentioned that possibility to me! How MANY other type2's in the world are living like this who "won't admit" they "WILL NEED TO START INSULIN" one day or get COMPLICATIONS as they get older and simply shrug thier shoulders and say quiely: it's my "Diabetes" getting worse!

Posted by Nicholas Dynes Gracey on 2 December 2007

Hi Robert Tanenberg, anonymous, AllieB2, ricklude, bird54 & AnyOne else,

bird54 You say: "Perhaps many people with diabetes get progressively worse because they work too hard at trying to control their blood sugar..."
... According to Robert Tanenberg's article ... MOST People '...with diabetes get progressively worse...'
... According to your abovementioned suggestion the reason for WHY ... any People '...with diabetes get progressively worse...' is because of working too hard at trying to REDUCE their blood glucose concentration.

In your opinion what proportion of People use 'diet & exercise' alone as compared with 'drugs & diet & exercise' as compared with 'drugs' alone to try to REDUCE their blood glucose?

... AND please confirm that it is your opinion that minimizing DISTRESS by means of adequate rest and/or sleep BETWEEN one meal & the next meal ie time & opportunity for full & proper DIGESTION may well be more effective than 'diet & drugs & exercise' ... in helping minimize an above average blood glucose concentration?

Any 'WORK' at trying to reduce a blood glucose concentration ... which is raised, by that body, as an adaptative mechanism [to PROTECT that body] is DISTRESSFUL.

Diabetes is NOT a disease [it is the associated 'HYPOglycemia' that is the 'disease'] ... diabetes aka HYPERglycemia [that can exist for years] is a 'physiological body state' that protects the nervous system [especially the brain] from the extraordinary dangers of beta-cell and/or HYPERinsulinemia [excess insulin] associated "relative-HYPOglycemia" [which starves the nervous system of fuel and can result in profound challenges within minutes or even seconds with little or zero notice].

Diabetes is NOT a disease … diabetes is the CURE [for relative-HYPOglycemia].

http://www.tinyurl.com/yqf8gj

'Relative-HYPOglycemia As A Cause Of Neuropsychiatric Illness' @ Journal Of The National Medical Association @ Harry M Salzer MD @ January 1966 @ Vol 58 @ Number 1 @ Table 1 @ Figure 2.

…FOR MORE related info on Adrenaline, Adrenalin LOVE, Chronic HYPERglycemia, Chronic Transient HYPERinsulinemia, Transient Supernormal Glycemia [TSG], Insulin Resistance [a protective adaptative process] AND Transient CARBOhydrate Overload… please follow the links via…

http://www.tinyurl.com/2k4n3a

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 23:59hrs SUN.02.DEC.2007.

www.DiabetesHealth.com/read/2007/12/03/5558.html
http://www.HealSelf.org/Diabetes.html
http://www.tinyurl.com/34lyyj
http://www.tinyurl.com/y7znor
http://www.tinyurl.com/2opc5h
http://www.tinyurl.com/yqf8gj

Posted by anonymous on 2 December 2007

Good article, but I worry about prolonged hyperinsulinemia and its effects on blood vessel disease, macro and micro. Also it causes weight gain as people snack and eat more to cope with a constant fear of hypoglycemia with barely concious feelings of sugar dropping too low triggering adrenalin and other alarms in the brain. Weight gain causes abdominal obesity increasing destructive hormone levels of hunger hormones, etc making many paradoxically more hungery for carbs and fat after they start a meal. Clearly exercise and insulin sensitizers like actos and glucophage help the resistance part but this alone cannot counteract the weight gain caused by the insulin. Gastroparesis would seem a problem for taking incretins. Is simply going on a strict carbohydrate weight loss diet a few days a month a better approach as I always feel incredibly better physically even though hungry and shaky when I do it in a way the medicines never come close. But as soon as I start to eat fully again, even with the meds, I begin feeling sluggish and gaining weight again. Also omega 3 and 6, vit e, c, and b's,(artificial and fish, veggie, fruit sources) and aspirin should in theory help blood vessel disease along with activity, but does it really?

Posted by bird54 on 2 December 2007

Dear Nick (and anyone else reading this),
In answer to your question, I don't know how many people use diet and exercise alone (without drugs) to control diabetes. I think that when diet and exercise become too frustrating in keeping blood sugars in the normal range, some people resort to drugs because their doctors scare them into believing that they will have a stroke or heart attack. (My doctor scares me so much that it gives me high blood pressure whenever I visit him. I told him that if I were going to have a stroke, it would be in his office and he would be the cause of it.) In addition, I know of people who use drugs as an easy way out, so that they can eat whatever they want.
Yes, it is my opinion that proper rest between meals does help to control blood sugar. Most of us eat on the run and don't take time to relax. We go to bed too late and are jolted out of bed in the morning by alarm clocks, which in itself is distressing. (On weekends, when I sleep in, my blood sugars are normal.)
It makes perfect sense to me that the real disease is hypoglycemia. Basic biology teaches kids about homeostasis, so why can't doctors accept the fact that the human body is able to keep everything in equilibrium? I believe that if we take proper care of our bodies, our bodies will heal themselves.
I agree with your statement, "Any 'WORK' at trying to reduce a blood glucose concentration ... which is raised, by that body, as an adaptative mechanism [to PROTECT that body] is DISTRESSFUL."
You could probably say the same thing about using drugs to control blood pressure and cholesterol.
Here's question for you: If Alzheimer's disease is being called type 3 diabetes because of insulin resistance in the brain, what protective mechanism is at work here? Why would the brain, which depends on glucose, and which makes its own insulin, want to keep out glucose?

Posted by Nicholas Dynes Gracey on 3 December 2007

Hi Robert Tanenberg, anonymous, AllieB2, ricklude, bird54, Ron Rosedale, Ladybird & AnyOne else,

bird54 You say: "If Alzheimer's disease is being called type 3 diabetes..."
http://tinyurl.com/3cpy57 [wei-qin_zhao@northwestern.edu]

... "Type 3 diabetes", [in respect of its apparently being CAUSED by "relative-HYPOglycemia" (as, apparently, is type 1 & type 2 diabetes)], is a reasonable name for a substantial reduction brain/memory capacity and/or 'Alzheimers'...
http://tinyurl.com/98bf2 [Suzanne_DeLaMonte_MD@Brown.edu]

Strokes arise in at least 3 forms, spasms, clots & bleeds. Why do You think there is just 1 name, in common use, to describe more than 3, vitally different, physiologies?

Which 'stroke' does your Doctor refer to (?) and please ask your Doctor to PLEASE identify JUST 1 [one] Peer-reviewed scientific reference, with an UNdrugTREATED control [ie comparing a Diabetic Group entirely UNdrugTREATED], ever published, that has ever evidenced [for Diabetics who are capable of drinking plenty of clean water]: (a) that glucose / insulin resistance is other than healthy(?) and/or (b) that the risk of a stroke is 'other than LESS' for an UNdrugTREATED type 2 Diabetic / Yourself.

Glucose / insulin "resistance" arises in at least 2 forms: (A) Insulin receptors which adaptively reduce their functional efficiency of 'pumping' glucose into cells; and (B) Insulin receptors that 'disappear' from cells. Why do You think there is just 1 name, in common use, to describe more than 2, vitally different, physiologies??

Type 1 & type 2 Diabetic ... glucose / insulin 'resistance' arises primarily via insulin receptors which adaptively down-regulate their rate of 'pumping' glucose into fat / liver / muscle cells ... so that more glucose is diverted/available for the brain / nervous system.
http://tinyurl.com/3aypqg [mristow@mristow.org]

Type 3 Diabetic ... glucose / insulin 'resistance' arises primarily via insulin receptors that 'disappear', from nerve cells, BECAUSE eating too OFTEN results in 'cycles' of localised brain / nerve damage & 'sclerosis scarring' [eg called 'Alzheimers' & 'peripheral neuropathy' ] via "relative-HYPOglycemia" ... which subsequently results in localised brain/nerve starvation c/o the 'glucose-starved HYPOglycemia', primary stage, followed by localised brain/nerve destruction during the "relative-HYPERglycemia", secondary stage, also called 'glucose re-perfusion'.
http://tinyurl.com/ynpp4g [raymond.swanson@ucsf.edu]

... In the absence of adaptative [protective] type 3 Diabetic glucose / insulin 'resistance' [aka brain-insulin receptor down-regulation] ... too OFTEN meal-induced 'glucose re-perfusion', via highly efficient nerve-insulin receptors, could induce massive neural damage relatively quickly [cf. youth-onset neuropathy].
http://tinyurl.com/yuh3q8 [mattisonj@mail.nih.gov]

Type 3 diabetes Is Caused By Food And Or Drug Administration Too Much And Or Too Often.
http://tinyurl.com/yta44e [giulio.passinetti@mssm.edu]

Pancreatic-insulin or 'digestion-insulin' [primarily for STORING glucose in fat, liver & muscle cells] for FUTURE use by the brain & nervous system] is usually produced by beta-cells following a period of eating. Brain-insulin or 'nerve-insulin' [primarily for CURRENT use to help with REGULATING glucose feeding into the nervous system] is produced by 'nerve cells' following a suitable period of sleep/eating less OFTEN.
http://www.tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]

Eating less OFTEN increases the number of brain-insulin receptors, increases the availability of glucose to the brain, reduces appetite and increases the availability of ketone fuel for the brain.
http://tinyurl.com/ys63gk [anson@jhu.edu]

Eating too often decreases the number of brain-insulin receptors, reduces the availability of glucose to the brain, increases appetite and reduces the availability of ketone fuel for the brain.
http://tinyurl.com/26jy4l [jens.bruening@uni-koeln.de]

Eating less is profoundly different from eating less OFTEN.
http://tinyurl.com/323nj3 [froelich@em.uni-frankfurt.de]

Blood glucose feeds the brain efficiently in the absence of any pancreatic-insulin because in the absence of food [ie following a sufficient period of sleep/fasting] the brain-insulin production is increased to help 'pump' the relatively lower levels of blood glucose into the nerves eg into the brain via brain-insulin receptors.
http://www.tinyurl.com/yr48jq [freychet@unice.fr]

Type 1, 2 or 3 Diabetes is NOT a disease [it is the associated 'HYPOglycemia' that is the 'disease'] ... type 1 & type 2 diabetes aka HYPERglycemia [that can exist for years] is a 'physiological body state' that protects the nervous system [especially the brain] from the extraordinary dangers of beta-cell and/or HYPERinsulinemia [excess insulin] associated "relative-HYPOglycemia" [which starves the nervous system of fuel and can result in profound challenges within minutes, or even seconds, with little or zero notice].
http://tinyurl.com/yu77y7 [m.henricsson@telia.com]

Type 1, 2 or 3 diabetes is NOT a disease … Type 1, 2 or 3 diabetes is the CURE [for relative-HYPOglycemia].
http://www.tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]

'Relative-HYPOglycemia As A Cause Of Neuropsychiatric Illness' @ Journal Of The National Medical Association @ Harry M Salzer MD @ January 1966 @ Vol 58 @ Number 1 @ Table 1 @ Figure 2.

In my opinion UNdrugTREATED type 2 diabetes [aka "cellular dietary restriction"] is a protective adaptative response which, by means of protecting the brain from "relative-HYPOglycemia", can be expected to reduce or eliminate type 3 diabetes aka 'Alzheimers'.
http://tinyurl.com/2farm9 [temorgan@usc.edu]

Please ask your current Specialist for advice including the provision of supporting Peer reviewed references evidencing their understanding of this important matter.
http://tinyurl.com/2lwbro [DrBernarr@aol.com]

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 15:33hrs MON.03.DEC.2007.

www.DiabetesHealth.com/read/2007/12/03/5558.html
http://HealSelf.org/Diabetes.html [DrBernarr@aol.com]
http://tinyurl.com/3cpy57 [wei-qin_zhao@northwestern.edu]
http://tinyurl.com/98bf2 [Suzanne_DeLaMonte_MD@Brown.edu]
http://tinyurl.com/3aypqg [mristow@mristow.org]
http://tinyurl.com/ynpp4g [raymond.swanson@ucsf.edu]
http://tinyurl.com/yuh3q8 [mattisonj@mail.nih.gov]
http://tinyurl.com/yta44e [giulio.passinetti@mssm.edu]
http://tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
http://tinyurl.com/ys63gk [anson@jhu.edu]
http://tinyurl.com/26jy4l [jens.bruening@uni-koeln.de]
http://tinyurl.com/323nj3 [froelich@em.uni-frankfurt.de]
http://tinyurl.com/yr48jq [freychet@unice.fr]
http://tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
http://tinyurl.com/yu77y7 [m.henricsson@telia.com]
http://tinyurl.com/2farm9 [temorgan@usc.edu]
http://tinyurl.com/2lwbro [DrBernarr@aol.com]

Posted by bird54 on 3 December 2007

Nicholas,
Thanks for all the excellent information and links. I've just finished reading most of the studies you referred to and am very excited about it. I'm going to try eating less often and see how I do. My father recently died of Alzheimers at the age of 90. I want to prevent it from happening to me!

Posted by anonymous on 4 December 2007

Nicholas Dynes Gracey,

I've very curious in your comments. I notice that you keep asking for evidence of the scientific postulates used by doctors in their treatments and yet you seem to keep using references from a BLOG. Indeed very scientific, yes, very evidence based. I hope those credentials you use serve you well, because your concepts on diabetes seem to be a throw-back to the days when the treatment for type 1 diabetes was starvation (qouting your comment: "UNdrugTREATED type 2 Diabetics and other healthy People should test daily with ChemStrips and pause from eating, and drink just water, until their urine is glucose free. The less carbohydrate eaten ... the less time between meals. That is how to CURE type 1 & type 2 Diabetes."
I recall a very interesting outcome of those patients...THEY ALL DIED!!!!!!

Posted by Nicholas Dynes Gracey on 4 December 2007

Hi Robert Tanenberg, anonymous, AllieB2, ricklude, Allison Love Beatty, Melody, Brent, Billy Warhol, Scott, BetterCell, Glenn, Jenny, David Beatty, bird54, Ladybird, Nick Trubov, Ron Rosedale, Diana Karaffa, Scott King, Linda von Wartburg, Nadia Al-Samarrie & AnyOne else...

bird54 You say: "Thanks for all the excellent information and links."
Please read & comment upon and/or at this information / link ...
http://tinyurl.com/29ornw [AlliesVoice.com]

... Your questions, with a apparent genuine desire for an answer [which is apparently quite rare], are most appreciated.

Levels of insulin need to be very carefully regulated and Athletes commonly have relatively extraordinary low basal levels of pancreatic-insulin. The less pancreatic-insulin the better ... unless more insulin is accompanied by an appropriate level of REGULATORY glucose / insulin resistance ... then arguably the more brain-insulin the better ...
http://tinyurl.com/3aypqg [mristow@mristow.org]

FORTUNATELY type 1, 2 or 3 diabetes all involve glucose / insulin resistance ... for example please comment on this reference ...
http://tinyurl.com/y7znor [hmdosch@sickkids.ca]

In my opinion type 1 Diabetics can benefit a great deal from glucose / insulin resistance [which appears to be one of the PROTECTIVE roles of C-peptide]. One of the functions of glucose / insulin resistance is to PROTECT the body from relative-HYPOglycemia. Apparently, from reading BetterCell's blog, it appears BetterCell's glucose / insulin resistance is relatively LOW ... especially on the day of his recent alarming challenges with apparent absolute-HYPOglycemia ...
http://tinyurl.com/2k6979 [BetterCell.blogspot.com]

It is certainly apparent that most type 1 Diabetics would benefit from MORE glucose / insulin resistance / C-peptide.
http://tinyurl.com/2eyxy3 [john.wahren@ki.se]

What's new about this understanding is understanding the profound similarities, in common, between type 1 & 2 & 3 diabetes ... all of which are apparently triggered & sustained [ie 'the CAUSE'] by 'cyclical neural starvation' of glucose availability aka "relative-HYPOglycemia".

Diabetes is NOT a disease [it is the associated 'HYPOglycemia' that is the 'disease'] ... diabetes aka HYPERglycemia [that can exist for years] is a 'physiological body state' that protects the nervous system [especially the brain] from the extraordinary dangers of ... beta-cell and/or HYPERinsulinemia [excess insulin] associated ... "relative-HYPOglycemia" [which starves the nervous system of fuel and can result in profound challenges within minutes or even seconds with little or zero notice].

Beta-cell and/or HYPERinsulinemia [excess insulin] associated "relative-HYPOglycemia" is the apparent reason, in my opinion, for adaptative down-regulation of beta-cells c/o the body's immune system [and could reasonably be described as 'Alzheimers of the beta-cell-brain'] ...
http://tinyurl.com/2rh6fz [hmdosch@sickkids.ca]

In my opinion UNdrugTREATED type 2 diabetes [aka "cellular dietary restriction"] is a protective adaptative response which, by means of protecting the brain from "relative-HYPOglycemia", can be expected to reduce or eliminate type 3 diabetes aka 'Alzheimers'.
http://tinyurl.com/2farm9 [temorgan@usc.edu]

bird54 You also say: "I'm going to try eating less often and see how I do."
Please read & comment upon this information link & associated links ...
www.thediabetesblog.com/2007/04/19/no-food-no-problem

Please ask your current Specialist for advice including the provision of supporting Peer reviewed references evidencing their understanding of this important matter.
http://tinyurl.com/2lwbro [DrBernarr@aol.com]

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 20:37hrs TUE.04.DEC.2007.

www.DiabetesHealth.com/read/2007/12/03/5558.html
http://HealSelf.org/Diabetes.html [DrBernarr@aol.com]
http://tinyurl.com/29ornw [AlliesVoice.com]
http://tinyurl.com/3aypqg [mristow@mristow.org]
http://tinyurl.com/y7znor [hmdosch@sickkids.ca]
http://tinyurl.com/2k6979 [BetterCell.blogspot.com]
http://tinyurl.com/2eyxy3 [john.wahren@ki.se]
http://tinyurl.com/2rh6fz [hmdosch@sickkids.ca]
http://tinyurl.com/2farm9 [temorgan@usc.edu]
www.thediabetesblog.com/2007/04/19/no-food-no-problem
http://tinyurl.com/2lwbro [DrBernarr@aol.com]

'Relative-HYPOglycemia As A Cause Of Neuropsychiatric Illness' @ Journal Of The National Medical Association @ Harry M Salzer MD @ January 1966 @ Vol 58 @ Number 1 @ Table 1 @ Figure 2.

Posted by bird54 on 4 December 2007

To Nick (and others),
My understanding of insulin resistance is that it is caused by consuming too many carbohydrates. (Dr. Bernstain's diabetes Solution). Type 1 diabetics develop insulin resistance from injecting too much insulin,(to counteract the high glucose levels from high carb diets) and type 2 diabetics develop insulin resistance from overworking their pancreases (from consuming too many carbs.) From the mice study where they compared mice on a restricted calorie diet vs. mice fed more food but less often, (every other day) the mice who ate more food, less often, did better. My only concern with eating more food, but less often is, that my blood sugar will spike and then drop too low resulting in relative hypoglycemia, which you say, is the real disease. I have been experimenting with eating less often but with more low carb RAW foods. My blood sugars have stayed in 60's, 70's and 80's. I don't know if 60 is too low for a type 2 diabetic since my body is able to compensate for it. I think that I may have reversed my diabetes from 2 years of low carb eating and exercising. I have also gone on periodic short fasts when my blood glucose starts to show a pattern of rising. Nick, I am confused about your statement that diabetes is not the disease but that relative hypoglycemia is. I can understand that hypoglycemia is worse than hyperglycemia, because a person can live years with hyperglycemia before developing complications, but die suddenly from hypoglycemia. Are you saying that people should not be concerned with OCCASSIONAL high blood sugar because the kidneys will filter it out? As long as one allows the body to filter it out by drinking lots of water, and blood glucose returns to normal, we need not be concerned? Accoring to Dr. Bernstein, anything above 90 is doing damage to the body, and recently I read that 180 postpranial spikes can cause a lot of damage. Is it only DRUG-treated diabetics that need to be concerned about high blood sugars? When I eat a high carb meal, my blood sugar spikes easily to 180+. That's why I eat only low carbs. So I don't know if my diabetes has actually gone away or if it is just under good control. For those interested in low carb, grainless, raw crackers, go to http://www.lydiasorganics.com/.

Posted by anonymous on 5 December 2007

To bird54,

Your comments are very well founded, although there are a few other theories to explain insulin resistance...As you indicated glucotoxicity (too much glucose at the level of the cells - note that this is significantly different from "eating too much carbohydrate") is one of the theories. Another one is the concept of lipotoxicity (too much lipid or fat) in which the breakdown products called free fatty acids change the way that the cells respond to the insulin. A third idea (and one that parallels the gluco and lipo-toxicity theories on a molecular level) is that of inflammation, which is in itself a very difficult entity to describe (although we all seem to know what it is...). Some of the chemicals that are increased in the setting of inflammation are cytokines which can also be increased directly by the presence of high glucoses (so I'm not sure why Nick implied earlier that hyperglycemia is safe since these cytokines are very harmful to the body). The bottom line is that the chemical structures that float around in the blood come in contact with the cells of our body and some of these chemicals (be it glucose, free fatty acids, cytokines, something scientists have yet to identify, or some combination thereof) enter the cells and interact with the proteins that are in our cells. These interactions include changing the physical structure of the protein making it so it is unable to do its job (think of it like putting a big wad of gum on a bicycle chain and then trying to go for a ride) - for those who want the science behind this, I encourage you to read about tyrosine phosphorylation of both the insulin receptor and the insulin receptor substrate type 1 (IRS-1) and then compare it the serine phosphorylation which is caused by the free fatty acids and cytokines. The unfortunate reality is that our bodies are very complex organ with lots of things there to try and protect itself from anything that it perceives is "not normal". Indeed that will include both hypoglycemia and hyperglycemia. Perhaps the best question to be asking is what does the body (or more specifically our own body) consider to be "normal"???

Posted by Nicholas Dynes Gracey on 5 December 2007

Hi Robert Tanenberg, anonymous, AllieB2, ricklude, Allison Love Beatty, Melody, Brent, Billy Warhol, Scott, BetterCell, Glenn, Jenny, David Beatty, bird54, Ladybird, Nick Trubov, Ron Rosedale, Diana Karaffa, Scott King, Linda von Wartburg, Nadia Al-Samarrie, Marianne Henricsson, Michael Ristow, Harry Salzer, Michael Anson, Toshio Maeda, Paul Tubiana, Bernarr Zovluck, Suzanne de la Monte, Debra Ann Fadool, Lee Iacocca & AnyOne else...

bird54 You say: "...According to..." and "...I read that..."
http://tinyurl.com/yu77y7 [m.henricsson@telia.com]

How do You know that what was said was true?
... Please identify a specific past reference that can be analysed in the context of 'right now'.

bird54 You also say: "My understanding of insulin resistance is that it is caused by consuming too many carbohydrates..."
http://tinyurl.com/3aypqg [mristow@mristow.org]

'Insulin resistance' should always be referred to as "Glucose Insulin Resistance".

... "Glucose Insulin Resistance" [GIR], if One is fortunate, creates sufficient 'resistance' to produce protective "Transient Supernormal Glycemia" [TSG] following a meal. TSG is supernormal, above average and type 2 diabetes mellitus ... so UNdrugTREATED type 2 Diabetics are evolved supernormal Human Beings that are successfully adapting to eating too often.

Type 0 Diabetics lack sufficient GIR to prevent "relative-HYPOglycemia" which CAUSES and helps define 'type 0 diabetes' [aka 'metabolic syndrome'] as ... a recurring brain starved state associated with neuropsychiatric illnesses including: Depression, Insomnia, Anxiety, Irritability, Crying Spells, Phobias, Lack of Concentration, Forgetfulness or Confusion, Unsocial or Antisocial Behavior, Restlessness, Psychosis, Suicidal Behavior; Exhaustion or Fatigue, Sweating, Tachycardia, Anorexia, Chronic Indigestion or Bloating, Cold Hands or Feet, Joint Pains, Obesity, Abdominal Spasm; Headache, Dizziness, Tremor [inward or external], Muscle Pains & Backache, Numbness, Blurred Vision, Muscular Twitching or Cramps, Staggering, Fainting or Blackouts and also Convulsions.
... 'Relative-HYPOglycemia As A Cause Of Neuropsychiatric Illness' @ Journal Of The National Medical Association @ Harry M Salzer MD @ January 1966 @ Vol 58 @ Number 1 @ Table 1 @ Figure 2.

In my opinion UNdrugTREATED type 2 diabetes aka "cellular dietary restriction" [CDR] is a protective adaptative response which, by means of GIR protects, the brain from "relative-HYPOglycemia" ... and [when encouraged] TSG, GIR and consequent CDR ... can ALSO be expected to reduce or eliminate type 3 diabetes aka 'Alzheimers'.
http://tinyurl.com/ys63gk [anson@jhu.edu]

... Why would any UNdrugTREATED type 2 Diabetic Person [who is capable of drinking sufficient clean water] seek to remove a protective adaptative [meal-induced] TSG response that protects that Person from relative-HYPOglycemia" c/o GIR?

It appears that any UNdrugTREATED 'alleged type 2 Diabetic' that experiences "relative-HYPOglycemia" is really a type 0 Diabetic who eats too OFTEN.
http://tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]

In my opinion all UNdrugTREATED type 1 Diabetics [eg newly DIAgnosed] should be treated with ... sufficient clean water and eating sufficiently less OFTEN to bring their TSG below their specific urination threshold EVERY time they eat. In your opinion ... What proportion of newly diagnosed type 1 Diabetics are really severely dehydrated type 0 or type 2 Diabetics that eat dehydrated carbohydrates too OFTEN for their particular urination threshold?
http://tinyurl.com/2arzxs [DiabetesCaseStudy.com]

Please ALSO ask your current Specialist for advice including the provision of supporting Peer reviewed references evidencing their understanding of this important matter.
http://tinyurl.com/2vp4e9 [DrBernarr@aol.com]

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 16:32hrs WED.05.DEC.2007.

www.DiabetesHealth.com/read/2007/12/03/5558.html
http://HealSelf.org/Diabetes.html [DrBernarr@aol.com]
http://tinyurl.com/yu77y7 [m.henricsson@telia.com]
http://tinyurl.com/3aypqg [mristow@mristow.org]
http://tinyurl.com/ys63gk [anson@jhu.edu]
http://tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
http://tinyurl.com/2arzxs [DiabetesCaseStudy.com]
http://tinyurl.com/2vp4e9 [DrBernarr@aol.com]

Posted by bird54 on 5 December 2007

Hi Nick,
I don't know if what I have heard or read is "true" or not. I get much of my information from http://www.sciencedaily.com/ and http://www.diabetesincontrol.com/. If I remember correctly, I recently read about the dangers of postpranial glucose spikes on diabetesincontrol.com. Tonight I searched through past issues, but I haven't located the article yet. I will keep trying. The article discussed the A1c. It stated that A1c's were deceiving because two people with the same A1c could have very different fluctuations in blood sugar, the most damaging being postpranial spikes, even more damaging than high fasting levels.
Nick, I am new to diabetes. I don't have the 27 years of knowledge that you possess. I was diagnosed 2 years ago. Dr. Bernstein's Diabetic Solution has helped me greatly. My doctors were useless in giving me any answers or explanations, so I have gone out searching on my own. I try to stay away from the doctor's office as much as possible, with the exception of my regular lab work, because no doctors have been able to help me with my history of fluctuating blood sugars in which I was diagnosed 30 years ago with reactive hypoglycemia. For years, doctors have ignored my complaints until I developed diabetes and now, suddenly, they won't leave me alone. They want to drug me with statin drugs and ACE inhibitors to prevent heart disease and other complications. Yet, my triglycerides are very low, my HDL is high, and my ratios are all great, so I don't understand why they are so overly concerned. My blood pressure does fluctuate, but I read a recent study on diabetesincontrol.com that states that blood pressure rises with postpranial spikes. I will look for that article too.
I've searched the internet but I can't find anything on "Type 0 diabetes". You say that it is metabolic syndrome, but when I google metabolic syndrome, it lists type 2 diabetes. According to your definition, I am a "type 0" because my blood sugar spikes after a high carb meal and then drops too low. Dr. Bernstein's explanation is that I lack the phase 1 insulin response. Eating less OFTEN seems to be working for me because it keeps my blood sugar steady all day and night. When I wake up, my fasting blood sugars are normal. Thank you for all the information. If people really want to find the truth about diabetes, they will search until they find it.

Posted by Nicholas Dynes Gracey on 6 December 2007

Posted by bird54 on 6 December 2007

To Nick and Anonymous,

Nick, Did you read the comments made by "anonymous" dated Dec. 5? I would like your opinion on it.

Anonymous, You said, "The unfortunate reality is that our bodies are very complex organ with lots of things there to try and protect itself from anything that it perceives is 'not normal'. Indeed that will include both hypoglycemia and hyperglycemia. Perhaps the best question to be asking is what does the body (or more specifically our own body) consider to be "normal"???

It would seem that our bodies already know what is "normal" and that is why I think medications can be dangerous. Our bodies have a wisdom of their own and are so complex that researchers have only seen the tip of the iceberg. Every time researchers discover some new enzyme or hormone in the body, they try to find a new drug to counteract it, or mimic it, (or whatever they do)and by interferring in one area, they create a problem in another area, because scientists do not know how the whole organism works. It is like the analogy you used of the "wad of gum in the bicycle chain," except that I am using that analogy to explain how medications gum up the workings of the human body.

The body is always trying to find balance (homeostasis), so my quesion is, "Why does the body get out of whack?" The human race has survived a long time on this earth without the need for medications. Of course, some died, but most adapted and thrived, otherwise we would not be here today. So my opinion is that we have deviated from nature and have consumed far too many calories, eaten too many refined junk foods, been exposed to toxins, and by so doing we have thrown our bodies out of balance. So diabetes and hypoglycemia are reactions to an unnatural lifestyle.

In the mice study, the mice who were fed the "normal" diet had average blood gluoses of 150. The mice that were fed a restricted calorie diet, and the mice that were fed on alternate days, both had blood glucoses of 100. So what is normal? It depends on their diet. Normality changes depending on what one eats. When I fast all day, my blood sugars range from 60 to 80. Is that normal? Yes, it seems so for my body, because that is how my body reacts to fasting. When I eat, my blood sugar rises according to what I eat, and how much I eat. Is that normal? It seems so. Blood sugar fluctuations are a normal response to eating and fasting. So the real question is, "What is healthy?" The results of the mice study show that eating less and eating less often both result in healthier mice.

However, I think type 1 diabetes has a different cause. It is caused by inflammation which causes the body to stop producing insulin. Without insulin, people die. The Toronto study showed that it was inflammation that caused the pancreas to stop producing insulin, and that when the inflammation was reversed, so was the diabetes. If type 1 is solely an autoimmune disease which destroys the beta cells, then how can dead beta cells produce insulin again AFTER the inflammation is gone? That tells me that the beta cells are not destroyed, but just inflammed, which makes them unable to produce insulin. So the cure to type 1 diabetes is to find a cure to inflammation.

Nick, You say that hypoglycemia is the real disease but that diabetes is the body's preferred state as a protective mechanism against hypoglycemia. Could you define "hypoglycemia"? By that, I mean, how low is low? Most of my hypoglycemic symptoms are from rapid dropping of blood sugar and not from being low. For example, while fasting, my blood sugar can be in the 60's with no symptoms. Yet, if I eat a high carb meal, my blood sugar will spike and then drop suddenly, resulting in shaking, sweating, irritability, at 70. It is the rapid drop that gives me my symptoms. I also get symptoms when my blood sugar is rising. Once after exercising, I was surprised to find my blood sugar at 50. I ate some glucose tablets and then the shaking started, as my blood sugar rose quickly to 90.
Does this mean that I am NOT insulin-resistant?

Posted by bird54 on 6 December 2007

To Nick and Anonymous,
Diabetes is a normal response to an abnormal lifestyle.

Posted by bird54 on 6 December 2007

To Anonymous,
I got so caught up in thinking about "what is normal" that I forgot to say "thank you" for your response regarding all the theories on insulin resistance. I will certainly look into "tyrosine phosphorylation" compared to "serine phosphorylation". I have no idea what that means, but I am curious to find out!

Posted by bird54 on 6 December 2007

To Nick,
You said, "PLEASE really do this ... have each & every One of your Doctors identify ANY Peer-reviewed scientific reference, with an UNdrugTREATED control [ie comparing a Diabetic Group entirely UNdrugTREATED], ever been produced, that has ever evidenced that type 2 Diabetics are less healthy UNdrugTREATED ?"
I will ask, however, I don't believe that anyone will ever compare UNdrugTREATED diabetics, because most of the research is funded by drug companies, and all they care about is making money by treating the chronic diseases they invent (like diabetes). If they can label it, then they can treat it.

Posted by Nicholas Dynes Gracey on 7 December 2007

Posted by bird54 on 7 December 2007

Nick,
How do you define eating "too often"? In the mice study, they fed the animals on alternate days. In your opinion, how often and how much should a person eat? In the mice study, the mice consumed twice as much food on the days they ate, thereby making up the lost calories for the previous day in which they had fasted. For a person with relative hypoglycemia, eating too much can result in huge blood sugar swings. In that case, wouldn't the standard treatment of six small meals be more beneficial in order to stabilize blood sugar? In other words, fast one day, and then graze the next day?

In the human study involving fasting diabetics, they discontinued the fast for those with either hyper or hypoglycemia. Again, HOW low is too low?

There's a book by titled, Adrenal Fatigue, by James L. Wilson. He states, "We have known for almost a century that people who suffer from low blood sugar frequently suffer from adrenal fatigue." Wilson's solution (among other things) is to get eat more often.

In your opinion, was I better off two years ago when my fasting blood sugars and A1c were higher? I thought that by improving my blood sugars I was "reversing" my diabetes, but have I in fact made my disease worse by increasing my episodes of relative hypoglycemia? I have to say honestly that I felt better when my blood sugar was higher than I do now, but as I mentioned earlier, my doctors scared the crap out of me when they diagnosed me with diabetes. It was like a death sentence, so my reaction has been to starve myself and overexercise in order to save my own life.

Posted by Nicholas Dynes Gracey on 8 December 2007

Posted by bird54 on 8 December 2007

To Nick and others,
If diabetes is caused by relative hypoglycemia, and hypoglycemia is caused by eating too often, then food is the cause of disease. Therefore, eating less often is the cure because it gives the body time to detox.
The question is: Is "food" the cause of this disease, or is food "intolerances"? It is known that many type 1 diabetics also have other autoimmune diseases, namely Celiac Disease (intolerance to the gluten in wheat, barley, and rye.) Studies have also suggested that casein (from milk) may trigger type 1 diabetes. Certain adenoviruses may trigger diabetes. The body mistakes these proteins and viruses with its own organs, triggering an autoimmune response.
In addition, many people react to the proteins in other foods such as eggs, soy, seafood, and corn. People with food allergies/sensitivities also suffer from adrenal fatigue/exhaustion. Food allergies cause relative hypoglycemia. That is one reason why they tell diabetics to test their blood sugar after meals. Some diabetics can tolerate some foods, while others can't. Food sensitivities cause rapid rises in blood sugar followed by rapid falls, resulting in hypoglycemia. Food intolerances also cause inflammation. Inflammation is the cause of all diseases, including cancer, arthritis, and diabetes.
Therefore, eating less often reduces inflammation, thereby curing these diseases.

Posted by bird54 on 8 December 2007

Hi Nick,
In response to the study you referred to http://tinyurl.com/2tp6vo [efeldman@umich.edu] regarding insulin resistance, why do you say that insulin resistance is good when the study states "Impaired glucose tolerance (IGT) serves as a marker for the state of insulin resistance and predicts both large- and small-vessel vascular complications, independent of a patient's progression to diabetes."? The study states that a blood sugar of 140-199 (below the diabetic level)at the 2 hr mark on a GTT suggests insulin resistance because the body does not allow glucose to enter the cells in a timely manner. They suggest that this delay is what causes all the complications. (Of course they do not mention a sharp rise at the one hour mark, followed by a large drop at 2 hours, which is what my body does. That implies that my body is not insulin resistant because my tissues absorb glucose in a VERY timely manner. My diabetic nurse commented to me, "You metabolize your food very quickly!" Please comment.

In the other study you referred to, http://tinyurl.com/ynpp4g [raymond.swanson@ucsf.edu], they state,
"...high blood glucose concentrations following hypoglycemic coma can initiate neuronal death..."
Dr. Bernstein suggests diabetics apply the "law of small numbers". In other words, use small amounts of glucose, calculated according to your body weight, to bring your body back to your targeted blood sugar. That is not the same as large amounts of glucose which cause a dangerous swing from too low to too high, which is what many diabetics do. Please comment.

Posted by AllieB2 on 9 December 2007

rDNA insulin CAUSES more inflammatioon throughout the body. Why would you CONSIDER introducing MORE inflammation to *reduce* blood sugar -- when in Type 2 diabetes -- it is INFLAMMATION that caused it in the first place?

Nowadays, a doctor is expected to prescribe a *fix* for his or her patient and send them on their way. However, taking into consideration NO INSULIN will HELP a TYPE 2 recover -- but rather IMPAIR a person with Type 2 diabetes -- why are people immune to understanding this?

The fact that we look upon insulin treatment for a person with Type 2 diabetes as an *OPTION* completely defies the HIPPOCRATIC OATH -- which states: "To please no one will I prescribe a deadly drug nor give advice which may cause his death."

Folks, even though what Nick says is very complex in wording -- it makes sense!!

The human body is the most miraculous machine on Earth! Allow it to heal itself and you will be gifted with the health He intended you to enjoy.

Posted by Nicholas Dynes Gracey on 9 December 2007

Posted by bird54 on 9 December 2007

To AllieB2,
You are right. Nick's writing is very complex. I am still trying to comprehend it.

Hi Nick,
I'm still reading and thinking about all of this information, so I'll get back to you. In the meantime, I have another question. You said, "PLEASE really do this ... have each & every One of your Doctors identify ANY Peer-reviewed scientific reference, with an UNdrugTREATED control [ie comparing a Diabetic Group entirely UNdrugTREATED], ever been produced, that has ever evidenced that type 2 Diabetics are less healthy UNdrugTREATED ?"
I understand and agree that there is no evidence that un-drug-treated diabetics are less healthy than drug-treated diabetics. My question: Is there evidence that un-drug-treated diabetics are less healthy than non-diabetics? Is there any evidence that hyperglycemia actually causes complications? If hyperglycemia is the cure to hypoglycemia, does there need to be a cure for hyperglycemia? If you were to list the types of diabetes on a spectrum, what order would you put them and what would come BEFORE type 0 diabetes?

Posted by draulakh on 10 December 2007

Dr Aulakh here.a diabetes specialist from india
I have seen many patients where HbA1C is more than 10,but everytime there FBS comes below 180 mg/dl {capillary}for last 2-3 months.WILL HbA1C be the absolue indication in all these cases for starting insulin therpay.

Posted by Nicholas Dynes Gracey on 10 December 2007

Hi Dr Aulakh,

No, a FBG 'fasting blood GLUCOSE' for 2/3 months averaging below 180mg/dl [ie below / between the average kidney threshold which naturally urinates excess blood glucose @ approximately 160mg/dl to 200mg/dl] is absolutely NOT an absolute indication, as proposed, in any cases for type 2 Diabetic Patients where HbA1c is more than 10.
http://en.wikipedia.org/wiki/HbA1c

What evidence, Peer reviewed or otherwise, raised the possibility, in your mind, that such a question may ever result in any answer other than no?

To what extent is your mind in favor of proposing and/or making recommendation, to your Patients, the drinking of clean water more OFTEN [as a meal replacement] and eating less OFTEN [to help reasonably extend the digestion recovery period from your Patients previous meal] so that their digestive processes can more fully digest each meal as will be better indicated by an average blood glucose readings target, for your Patients, of approximately 160mg/dl or less.

UNdrugTREATED type 2 Diabetics can handle plenty of carbohydrate ... They need to drink more water because they 'handle' excess carbohydrate simply by urinating excess glucose [water-soluble] just like most People urinate excess water-soluble vitamins and excess urea.
...http://en.wikipedia.org/wiki/Renal_threshold

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 17:23hrs MON.10.DEC.2007.

www.DiabetesHealth.com/read/2007/12/03/5558.html
http://HealSelf.org/Diabetes.html [DrBernarr@aol.com]
http://en.wikipedia.org/wiki/HbA1c
http://en.wikipedia.org/wiki/Renal_threshold

Posted by Nicholas Dynes Gracey on 10 December 2007

Hi Seale Harris, Martin Buehler, Harry Salzer, Robert Tanenberg, anonymous, AllieB2, ricklude, Allison Love Beatty, Melody, Brent, Billy Warhol, Scott, BetterCell, Glenn, Jenny, David Beatty, bird54, Ladybird, Nick Trubov, Ron Rosedale, Diana Karaffa, Lissa Coffey, Scott King, Linda von Wartburg, Nadia Al-Samarrie, Marianne Henricsson, Michael Ristow, Michael Anson, Toshio Maeda, Paul Tubiana, Bernarr Zovluck, Suzanne de la Monte, Debra Ann Fadool, Ricardo Branco, Francesca Messina, Matthew Sadgrove, Lee Iacocca, Anthony Colpo, Shane Ellison, Duane Graveline, Malcolm Kendrick, Joel Fuhrman, Byron Richards, Joel Kauffman, Jerrold Olefsky, Martin Rutter, Bernard Zinman, Saul Malozowski, David Zangen, Eva Feldman, Gail Owen, Philip Cryer, Alan Dyer, Robert Turner, Rury Holman, Ernst Chantelau, Eva Kohner, Venkat Narayan, Jonathan Levy, Trayana Djarova, Sarimari Tupola, Peter Butler, Dr Aulakh & AnyOne else...

The new proposal is that HYPERglycemia [90 -160 mg/dl] represents above the average [70 - 90 mg/dl] 'fasting blood glucose' [FBG], a 'transient supranormal glycemia' [TSG] level, which if supported [especially with adequate hydration (clean water)], always has a net-beneficial-effect on the body, the purpose of which is to improve the availability of fuel availability to the nervous system [especially the brain] during times of increased need / imminent need ... and is a natural PROTECTIVE mechanism that the body inherently supports by means including 'glucose insulin resistance' [GIR] which also always has a net-beneficial-effect on the body ... as compared with most Scientists current views ... that HYPERglycemia & GIR have a net-negative-effect on the body ...
... http://en.wikipedia.org/wiki/Hyperglycemia

There are many many ways in which GIR fulfills its physiological adaptation ... regulating the cellular entry of GLUCOSE via each cell's individual INSULIN receptor RESISTANCE ... GIR all for helping to regulate nerve/brain fueling [as a priority over any other 'organ' of the body].

More insulin / insulin receptors = less GIR; and
Less insulin / insulin receptors = more GIR ...

bird54 Your 'type 0 & 1 & 2 & 3 & 4 diabetes' / 'diabetes-free' Question states: "Is there evidence that un-drug-treated diabetics are less healthy than non-diabetics?

Yes, for type 0 diabetes ... this 'pre-diabetes-diabetes' aka 'IGT' aka 'syndrome X' aka 'reactive hypoglycemia' aka 'idiopathic syndrome' aka 'metabolic syndrome', although first called 'DYSinsulinism' [by Seale Harris in 1924], was better classified as 'relative-HYPOglycemia' [by Martin Buehler in 1962 & Harry Salzer in 1966] ... because ... 'normal' is ALWAYS relative to change. Evidenced by the extraordinary list of symptoms experienced by type 0 Diabetics ... evidenced in this document ...
... 'Relative-HYPOglycemia As A Cause Of Neuropsychiatric Illness' @ Journal Of The National Medical Association @ Harry M Salzer MD @ January 1966 @ Vol 58 @ Number 1 @ Table 1 @ Figure 2.

Yes, for type 1 diabetes where a particular alleged type 1 Diabetic Patient actually has ZERO pancreatic insulin production / recoverable pancreatic insulin production on the day of diagnosis [ie pre-ANYdrugTREATED] ... my reply question to that is ... how often does such a Person EVER appear ?
... http://tinyurl.com/2arzxs [DiabetesCaseStudy.com]
http://tinyurl.com/2l65kn [biol1@telconet.co.zw ]
http://tinyurl.com/2gcjdn [francesca_messina@yahoo.it]
http://tinyurl.com/y7znor [ hmdosch@sickkids.ca]
http://tinyurl.com/2jscjt [pbutler@mednet.ucla.edu]
http://tinyurl.com/2734xt [pbutler@mednet.ucla.edu]
http://tinyurl.com/2n9m9c [pbutler@mednet.ucla.edu ]

No, for type 2 diabetes because well-hydrated UNdrugTREATED type 2 Diabetics have evolved suitably lowered nerve/brain GIR and/or suitably raised pancreatic GIR which results in transient supranormal glycemia [TSG] in response to a western diet and TSG appears to protect against meal induced relative-HYPOglycemia, in an 'exercise-free' manner, more effectively than the diabetes-free response of necessary physical exercise eg a 'post-meal walk' to prevent type 0 Diabetic complications arising.
... http://tinyurl.com/3aypqg [mristow@mristow.org]
http://tinyurl.com/2gtz93 [ sarimari.tupola@helsinki.fi]

Yes, for type 3 diabetes because Alzheimers & Parkinsons Patients [type 3 Diabetics] usually make ZERO changes to their diet ... changes that could relatively easily help prevent & progressively reduce their daily challenges with relative-HYPOglycemia which manifest as symptoms characteristic of cyclical neural/brain fuel starvation and too rapid glucose re-perfusion eg c/o repetitive daily glucose od snacks.
... http://tinyurl.com/ynpp4g [raymond.swanson@ucsf.edu]

Yes, for type 4 diabetes because Pregnant Patients usually make ZERO effective 'relative-HYPOglycemia preventative' changes to their diet ... changes that could relatively easily help prevent & progressively reduce their daily challenges with relative-HYPOglycemia which manifest as HYPERglycemic symptoms characteristic of 'Child protection' against potential cyclical neural/brain fuel starvation of any growing baby and potential too rapid glucose re-perfusion [of the 'sensitive' relatively fast-growing nerve/brain cells] eg c/o repetitive daily glucose over-dose [od] snacks.
... http://tinyurl.com/3ybwq4 [adyer@northwestern.edu]

bird54 Your 'HYPERglycemia' Question states: "Is there any evidence that hyperglycemia actually causes complications?"

If there is AnyOne who is aware of alleged evidence for above-average 'fasting blood glucose' [FBG] of 90 -160 mg/dl HYPERglycemia causing an other than net-beneficial effect upon the body... please identify the key reference that persuades your mind of that.

2 types of HYPERglycemia include ... (a) Transient Supranormal Glycemia [TSG] where ... when eg a meal leads to an acute DISTRESS-response of excess blood glucose being urinated by the kidneys as a 'calculated' reduction of the glucose concentration to less than approximately 160 - 200 mg/dl; and (b) chronic HYPERglycemia where there is chronic DISTRESS-response eg following a trauma [that persists longer than the time taken to properly digest 'One Meal'].
... http://tinyurl.com/3yuhzg [brancori@terra.com.br]

bird54 Your other 'HYPERglycemia' Question states: If hyperglycemia is the cure to hypoglycemia, does there need to be a cure for hyperglycemia?

In my opinion the HYPERglycemia [in the presence of adequate hydration] is always protective as long as it is allowed to reduce blood glucose naturally back to below 160 -200 mg/dl by removing the DISTRESS and/or eating less OFTEN.

PLEASE AnyOne "type 2 Diabetic" really do this ... have each & every One of your Doctors identify ANY Peer-reviewed scientific reference, with an UNdrugTREATED control [ie comparing a Diabetic Group entirely UNdrugTREATED], ever been produced, that has ever evidenced that type 2 Diabetics are less healthy UNdrugTREATED ?"
... http://tinyurl.com/2d48d5 [juangrun@mail.med.upenn.edu]
http://tinyurl.com/3xdso9 [evakohner@gmail.com]
http://tinyurl.com/34lyyj [lobnig@med.uni-duesseldorf.de]
http://tinyurl.com/2tsuum [zinman@mshri.on.ca]
http://tinyurl.com/2ozw5s [rury.holman@dtu.ox.ac.uk ]
http://tinyurl.com/yo9eq3 [ukpds@dtu.ox.ac.uk]
http://tinyurl.com/2wrk2q [ rury.holman@dtu.ox.ac.uk]
http://tinyurl.com/2xwyaw [webmaster@servier.com]
http://tinyurl.com/298jat [jonathan.levy@drl.ox.ac.uk]
http://tinyurl.com/3x45zf [kav4@cdc.gov]
http://tinyurl.com/yk8dvf [dnathan@partners.org]
http://tinyurl.com/2ve6pv [pcryer@wustl.edu]
http://tinyurl.com/35sfwq [dnathan@partners.org]
http://tinyurl.com/ywnrs6 [ diabetescare@diabetes.org]
http://tinyurl.com/2tbry7 [dnathan@partners.org]

bird54 Your 'type 0' Question states: "If you were to list the types of diabetes on a spectrum, what order would you put them and what would come BEFORE type 0 diabetes?"

Relative-HYPOglycemia [aka nerve/brain fuel starvation DISTRESS] without 'eating less OFTEN & drinking more clean WATER' becomes ...

Type 0 diabetes pancreatic GIR adapted to type 1 diabetes to survive acute Relative-HYPOglycemia short term.
Type 0 diabetes pancreatic GIR adapted to type 2 diabetes to survive chronic Relative-HYPOglycemia long term.
Type 0 diabetes nerve/brain GIR adapted to type 3 diabetes to survive chronic Relative-HYPOglycemia short term.
Type 0 diabetes pancreatic GIR adapted to type 4 diabetes to survive acute Relative-HYPOglycemia pregnancy/gestation term.
What comes BEFORE type 0 diabetes is a well-hydrated UNdrugTREATED lifestyle, including adaptable stresses that increasingly strengthen the Human body with the help of adequate nourishment and 'digestion-time' between each meal.

Diabetes is NOT a disease … diabetes is the CURE [for relative-HYPOglycemia].

1. Please comment upon: Debra Fadool's 2000 paper in relation to increasing nerve/brain GIR and preventing relative-HYPOglycemia.
... http://tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]

2. Please comment upon: Toshio Maeda's 2001 paper in relation to increasing pancreatic GIR and preventing relative-HYPOglycemia.
... http://tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]

3. Please comment upon: Michael Anson's 2003 paper in relation to increasing pancreatic GIR, reducing nerve/brain GIR and preventing / CURING relative-HYPOglycemia, Alzheimers & Parkinsons.
... http://tinyurl.com/ys63gk [anson@jhu.edu]

4. Please comment upon: Michael Ristow's 2007 "Glucose Restriction..."[aka 'Glucose Insulin Resistance' ("GIR")] paper in relation to Fadool's, Maeda's & Anson's papers and eating less OFTEN for increasing pancreatic GIR, reducing nerve/brain GIR and preventing / CURING relative-HYPOglycemia, Alzheimers & Parkinsons.
... http://tinyurl.com/3aypqg [mristow@mristow.org]

How much clearer?

To better understand how profound relative-HYPOglycemia can be ... consider "relative-HYPOthermia" and feelings of 'peripheral neuropathy' ... eg in the summer suddenly being actually too cold [cf relative-HYPOglycemia @ 125 mg/dl HYPERglycemia] by going for a swim too suddenly after sun-bathing ... body had happily adapted to sun-bathing HYPERthermia [cf transient supranormal glycemia @ 150 mg/dl] but on jumping into a sea ... perceives that the water is actually now relatively too cold even though the sea temperature is absolutely 'quite warm' [ie 125 mg/dl HYPERglycemia whilst 'above-average', is in the particular adaptation circumstances actually CAUSING 'nerve/brain-numbing / glucose-starving' relative-HYPOglycemia] ... probably followed by an inflammatory 'glucose re-perfusion' neuropathic snack to psychologically help warm-up from the alleged cold swim.
... http://tinyurl.com/ynpp4g [raymond.swanson@ucsf.edu]

Please AnyOne ALSO ask your current Specialist for advice including the provision of supporting Peer reviewed references evidencing their understanding of this important matter.
... http://tinyurl.com/2vp4e9 [DrBernarr@aol.com]

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 20:12hrs MON.10.DEC.2007.

www.DiabetesHealth.com/read/2007/12/03/5558.html
http://HealSelf.org/Diabetes.html [DrBernarr@aol.com]
http://en.wikipedia.org/wiki/Hyperglycemia
'Relative-HYPOglycemia As A Cause Of Neuropsychiatric Illness' @ Journal Of The National Medical Association @ Harry M Salzer MD @ January 1966 @ Vol 58 @ Number 1 @ Table 1 @ Figure 2.
http://tinyurl.com/2arzxs [DiabetesCaseStudy.com]
http://tinyurl.com/2l65kn [biol1@telconet.co.zw]
http://tinyurl.com/2gcjdn [francesca_messina@yahoo.it]
http://tinyurl.com/y7znor [hmdosch@sickkids.ca]
http://tinyurl.com/2jscjt [pbutler@mednet.ucla.edu]
http://tinyurl.com/2734xt [pbutler@mednet.ucla.edu]
http://tinyurl.com/2n9m9c [pbutler@mednet.ucla.edu]
http://tinyurl.com/3aypqg [mristow@mristow.org]
http://tinyurl.com/2gtz93 [sarimari.tupola@helsinki.fi]
http://tinyurl.com/ynpp4g [raymond.swanson@ucsf.edu]
http://tinyurl.com/3ybwq4 [adyer@northwestern.edu]
http://tinyurl.com/3yuhzg [brancori@terra.com.br]
http://tinyurl.com/2d48d5 [juangrun@mail.med.upenn.edu]
http://tinyurl.com/3xdso9 [evakohner@gmail.com]
http://tinyurl.com/34lyyj [lobnig@med.uni-duesseldorf.de]
http://tinyurl.com/2tsuum [zinman@mshri.on.ca]
http://tinyurl.com/2ozw5s [rury.holman@dtu.ox.ac.uk]
http://tinyurl.com/yo9eq3 [ukpds@dtu.ox.ac.uk]
http://tinyurl.com/2wrk2q [rury.holman@dtu.ox.ac.uk]
http://tinyurl.com/2xwyaw [webmaster@servier.com]
http://tinyurl.com/298jat [jonathan.levy@drl.ox.ac.uk]
http://tinyurl.com/3x45zf [kav4@cdc.gov]
http://tinyurl.com/yk8dvf [dnathan@partners.org]
http://tinyurl.com/2ve6pv [pcryer@wustl.edu]
http://tinyurl.com/35sfwq [dnathan@partners.org]
http://tinyurl.com/ywnrs6 [diabetescare@diabetes.org]
http://tinyurl.com/2tbry7 [dnathan@partners.org]
http://tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
http://tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
http://tinyurl.com/ys63gk [anson@jhu.edu]
http://tinyurl.com/3aypqg [mristow@mristow.org]
http://tinyurl.com/ynpp4g [raymond.swanson@ucsf.edu]
http://tinyurl.com/2vp4e9 [DrBernarr@aol.com]

Posted by bird54 on 10 December 2007

Hi NIck,
WOW! Impressive!
You have convinced me. I've read the links you listed, but I'm not done analyzing them yet, so I may have more question later. As the saying goes ..."inquisitive minds want to know..."
I've been fasting all day (just drinking water) and eating in the evening when I get home from work, Last week I lost 5 pounds. I feel fine--more relaxed and less irritable, probably due to less blood sugar swings.

Posted by Nicholas Dynes Gracey on 11 December 2007

Hi bird54 ...

Am really grateful. One meal a day is the medical foundation for the health benefits of eating less OFTEN ... and truly treating relative-HYPOglycemia ... sustainably.

Please share an outline of your success with the Health Editors of ALL your favorite on-line / off-line ... newspapers / magazines and please TELL them ASAP that the NEW evidence for the CAUSE & CURE for diabetes is EVIDENCED at Diabetes Health, right now, at ... www.DiabetesHealth.com/read/2007/11/29/5564.html

Please help bring the benefits of drinking water more OFTEN and eating LESS often to ALL types of Diabetics ASAP.

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 13:01hrs TUE.11.DEC.2007.

www.DiabetesHealth.com/read/2007/12/03/5558.html
http://HealSelf.org/Diabetes.html [DrBernarr@aol.com]
http://tinyurl.com/2bjav4 [atila.sandor@aok.pte.hu]
http://tinyurl.com/28lr3g [barbara.cannon@wgi.su.se]
http://tinyurl.com/2gjguq [jamie.timmons@gmail.com]
http://tinyurl.com/29rzun [tschoemh@ucmail.uc.edu]
http://tinyurl.com/2nd93r [j.hansen@imbg.ku.dk]
http://tinyurl.com/37doxu [jan@metabol.su.se]

Posted by Nicholas Dynes Gracey on 12 December 2007

Posted by bird54 on 12 December 2007

Hi Nick,
I will definitely share this information with others. I have already shared it my friends and coworkers. Keep it up!

Posted by AllieB2 on 12 December 2007

Study after study is proving that insulin administration (and some oral meds) force the body to cram glucose into cells that cannot handle it! This results in destroying the cell membranes and exacerbating the complications of Type 2 diabetes resulting in heart attack and stroke. Insulin combined with excess sugar in the blood stream is a recipe for heart attack and stroke.

Type 2 diabetes puts a person at higher risk for heart attack and stroke. YES - it's very important to control blood sugar, but do so by reducing the types of foods that caused the **inflammation** in the first place. Type 2 diabetes is caused by inflammation by cells not wanting to absorb the glucose from the blood.

The body cannot handle the glucose in the cells and cries UNCLE for the person to stop forcing it into cells. Using drugs to make this happen is not *solving* the problem of elevated blood sugar. It's only moving the *problem* from one area of the body to the next. Like cleaning-up a messy room -- is it really *clean* if you just move all the junk from the floor into the closet in a big pile?

Using insulin to override the natural response of the body is causing the complications of diabetes. Treating Type 2 diabetes with exogenous insulin is traumatic to the body and impairs blood flow resulting in a litany of explosive resistance.

The following is clinical significance explaining why complications arise when reductions in blood sugar for Type 2 diabetes are damaging to the retina. The kidneys, brain, and central nervous system APPLY to this, as well: http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3323985&dopt=AbstractPlus

Allison Love Beatty - Founder of "Allies Voice"
Making the World Safer for People with Diabetes
http://www.alliesvoice.com/

Posted by Nicholas Dynes Gracey on 13 December 2007

Posted by bird54 on 14 December 2007

Hi Nick,
Have you thought about writing a book explaining your theory and cure for diabetes?

Posted by Nicholas Dynes Gracey on 14 December 2007

Posted by Scott King on 13 December 2007:-

"... How Can We Stop the CRISIS in Diabetes Education? Tell Us How!
... www.DiabetesHealth.com/read/2007/12/13/5587.html

Hi Seale Harris, Martin Buehler, Harry Salzer, Robert Tanenberg, anonymous, AllieB2, ricklude, Allison Love Beatty, Melody, Brent, Billy Warhol, Scott, BetterCell, Glenn, Jenny, David Beatty, bird54, Ladybird, Nick Trubov, Ron Rosedale, Diana Karaffa, Lissa Coffey, John Manley, Bill Corey, MEC, Harry Thompson, Nicholas Rheinberg, Brian Rodgers, Scott King, Linda von Wartburg, Nadia Al-Samarrie, Marianne Henricsson, Michael Ristow, Michael Anson, Toshio Maeda, Paul Tubiana, Bernarr Zovluck, Suzanne de la Monte, Debra Ann Fadool, Ricardo Branco, Matthew Sadgrove, Lee Iacocca, Anthony Colpo, Shane Ellison, Duane Graveline, Malcolm Kendrick, Joel Fuhrman, Byron Richards, Joel Kauffman, Jerrold Olefsky, Martin Rutter, Bernard Zinman, Saul Malozowski, David Zangen, Eva Feldman, Gail Owen, Philip Cryer, Alan Dyer, Robert Turner, Rury Holman, Ernst Chantelau, Eva Kohner, Venkat Narayan, Jonathan Levy, Trayana Djarova, Sarimari Tupola, Peter Butler, Dr Aulakh, Juan Grunwald, Maurizio Vanelli, Francesca Messina, Ben Bloom, Stefan Herget-Rosenthal, Mariana Ruiz Villarreal & AnyOne else...

Please help expose the CAUSE [etiology]...

21,000,000 DIABETICS ...

Joy Pape says: "...we have almost 21 million people with diabetes but only about 15,000 CDEs..."
... www.DiabetesHealth.com/read/2007/12/13/5582.html

ETIOLOGIES ARE not KNOWN ? ...

The ADA says: "...Type 2 diabetes (ranging from predominantly insulin resistance with relative insulin deficiency to predominantly an insulin secretory defect with insulin resistance)
This form of diabetes, which accounts for ~90–95% of those with diabetes, previously referred to as non-insulin-dependent diabetes, type II diabetes, or adult-onset diabetes, encompasses individuals who have insulin resistance and usually have relative (rather than absolute) insulin deficiency At least initially, and often throughout their lifetime, these individuals do not need insulin treatment to survive. There are probably many different causes of this form of diabetes. Although the specific etiologies are not known, autoimmune destruction of ß-cells does not occur, and patients do not have any of the other causes of diabetes listed above or below..."
... 2007 http://tinyurl.com/ywnrs6 [diabetescare@diabetes.org]
... 2007 http://en.wikipedia.org/wiki/Etiology

SUPPORT ...

President George W Bush says: "...We will continue to support NIH scientists and others working to treat and cure this disease..."
... 2003 http://tinyurl.com/38x7xr [WhiteHouse.gov]
... 2007 http://tinyurl.com/2dw2q2 [LoveDiabetes.com]

PROVING 'TYPE 2' DISPROVES 'TYPE 1' ...

Paul Tubiana says: "...It is very difficult to cure diabetes when insulin dependent diabetic children wrongly believe that they have type 1 diabetes, when in reality they have type 2 diabetes (insulin resistance) because they were not told by healthcare professionals about the stimulated C-Peptide test ... diabetics are being wrongly misled and confused to believe they have type 1 diabetes, just because they use insulin ... Many basic questions about diabetes have remained unasked and unanswered over the past 30 years ... Why has the C-Peptide test which has existed since the early 1970's not been utilized?

When the question is asked: Have most juvenile, insulin dependent, and type 1 diabetics been individually C-Peptide tested? The answer will be: NO. It will be surprising to most non-diabetics and diabetics alike that Endocrinology (the study of glands) often does not check the pancreas (a gland.)

It is wrong to automatically assume that juvenile, insulin dependent, or "type 1" diabetes is caused by a problem with the pancreas. Type 2 diabetes means that the pancreas works and even produces insulin above normal levels (also known as insulin resistance). Type 2 diabetes is not caused by the pancreas. Proving type 2 diabetes disproves type 1 diabetes.

Juvenile diabetes is an outdated term that should no longer be valid with the C-Peptide test. The C-Peptide test is virtually unknown to most diabetics although it has existed since the early 1970's.

We feel that it is time that diabetic children and their families be freed from the evil lie of "type 1" diabetes and to give them new hope that their health condition is actually within reach of a cure because they actually still produce enough of their own insulin. It is time that all insulin dependent, juvenile, and so-called "type 1" diabetics be Stimulated C-Peptide Tested or at least be informed about the existence of this test. And that by exposing this it will result in more targeted research which will benefit all diabetics. ..."
... 2007 http://tinyurl.com/2arzxs [DiabetesCaseStudy.com]

SO...

It appears that MORE than 90% of Diabetics have "type 2" diabetes.

UNdrugTREATED type 2 diabetes is 'curable' [if desirable] without being ANYdrugTREATED for 'glucose-lowering'.

If 90% of Diabetics, diagnosed with type 1 diabetes, really had type 2 diabetes [eg possibly Halle Berry] ... but because of the lack of administration of a simple test [the '1972' C-Peptide test] were mistakenly diagnosed as type 1 ... then virtually all Diabetics, before being ANYdrugTREATED, for 'glucose-lowering', were actually type 2 Diabetics and therefore CURABLE 'as-of-1970' [ie more than 37 years ago].
... www.DiabetesHealth.com/read/2007/11/02/5548.html
... 2007 http://en.wikipedia.org/wiki/C-peptide

NOW [more than 35 years since 1972] ...

In my opinion, founded upon more than 27 years of diabetes associated research, is that UNdrugTREATED type 2 Diabetics are STRONGER & HEALTHIER than the average Person of the same age.

BEFORE...

Being ANYdrugTREATED for 'glucose-lowering' ... it is reasonable to believe that evidence MUST exist to provide proof that being ANYdrugTREATED, for 'glucose-lowering', does not HARM type 2 Diabetics.

Before or since 1972 ... Where is the proof [ie comparing a 'type 2' Diabetic Group entirely UNdrugTREATED] that being ANYdrugTREATED, for 'glucose-lowering', does not HARM type 2 Diabetics?

PLEASE identify [or have your Doctor or diabetes Nurse/CDE or diabetes clinic identify] ANY Peer-reviewed scientific reference, with an UNdrugTREATED control [ie comparing a 'type 2' Diabetic Group entirely UNdrugTREATED for 'glucose-lowering'], that has ever been produced, that has ever evidenced that type 2 Diabetics are less healthy UNdrugTREATED for 'glucose-lowering'?

What if there is ZERO reference [ie comparing a 'type 2' Diabetic Group entirely UNdrugTREATED for 'glucose-lowering'] anywhere, before or since 1972, that provides Peer-reviewed evidence that ANYdrugTREATED, for 'glucose-lowering', is better than UNdrugTREATED, for 'glucose-lowering', for all type 2 Diabetics?

Please AnyOne identify just 1 such reference [ie comparing a 'type 2' Diabetic Group entirely UNdrugTREATED for 'glucose-lowering'].

In the continued absence of any such reference it is reasonable to suppose that every type 2 Diabetic 'complication' arises as a result of the treatment of the 'insulin resistance' that was actually keeping type 2 Diabetics stronger & healthier than the average Person ... in the first place.
... 2007 http://tinyurl.com/3bcr7h [LoveDiabetes.com]

WHO IS RESPONSIBLE ? ...

Presumably, in respect of 'Who is ultimately responsible for any consequential side-effects of 'glucose-lowering'?' ... such a reference should be producible by a GP or an MD or any other prescribing Physician BEFORE or during treating ANY of their type 2 Diabetic Patients...

The Hippocratic Oath says: "...To please no one will I prescribe a deadly drug nor give advice which may cause his death..."
... 2007 www.aapsonline.org/ethics/oaths.htm [AAPSonline.org]
... 2006 http://tinyurl.com/2gtyp4 [Roy_Poses@Brown.EDU]
... 2007 http://en.wikipedia.org/wiki/Euthanasia
... 1950 http://tinyurl.com/345uzh [TIME.com]
... 2007 http://tinyurl.com/3xv8y2 [ lsn@lifesite.net]

EVIDENCE...

Suggests that being ANYdrugTREATED to reduce plasma blood glucose [PBG] is VERY harmful to type 2 Diabetics ... for example ...

'... Why some cases of retinopathy worsen when diabetic control improves ... the rate of fall of blood glucose concentration and the accompanying reduction in blood flow have been thought to be the trigger ... This suggestion was supported by the finding of Grunwald et al, who showed a 20% reduction of blood flow when blood glucose concentrations fell from about 15 mmol/l to 8 mmol/l.'
... 1987 http://tinyurl.com/2d48d5 [juangrun@mail.med.upenn.edu]
... 1997 http://tinyurl.com/34lyyj [lobnig@med.uni-duesseldorf.de]

As compared with the relative HIGH / JOY of UNdrugTREATED type 2 diabetes and transient supranormal glycemia [TSG].

IF...

More than 90% of Diabetics have type 2 diabetes [18.9 million People] ... and more than 90% of type 1 Diabetics have type 2 diabetes [1.89 million People] ... which is curable ... then approximately 99% of all diabetes is quickly curable and approximately only [21 million - (18.9 + 1.89)] = 0.21 million Diabetics have "type 1a" ['auto-immune'] diabetes.

According to Joy Pape there are approximately 15,000 CDE's.

0.21 million type 1a Diabetics = approximately 210,000 type 1a Diabetics divided between 15,000 CDE's = 14 Diabetics who appear to require Diabetic drug treatment. One CDE averaging less than 15 Patients solves the alleged 2007 crisis that apparently started in the 1970's.

Scott King PLEASE do this ...

PLEASE investigate deeply and study/inspire deeply and inform widely the TRUTH about the 'missing-research' ... research & DEMAND an explanation for the lack of research that allegedly justifies [21 million - 0.21 million ] 20,790,000 Diabetics being ANYdrugTREATED, for 'glucose-lowering', in the absence of ANY evidence [including an UNdrugTREATED control 'type 2' Diabetic Group (for 'glucose-lowering')] that can reasonably justify such alarming & questionable 'glucose-lowering' treatment [aka HYPOglycemic treatment aka "Anti-diabetic_drug" treatment].
... 2007 http://en.wikipedia.org/wiki/Anti-diabetic_drug

Scott King, Linda von Wartburg, Nadia Al-Samarrie, Suzanne de la Monte & AnyOne PLEASE do this ...

PLEASE identify [or have your Doctor or diabetes Nurse/CDE or diabetes clinic identify] ANY Peer-reviewed scientific reference, with an UNdrugTREATED control [ie comparing a 'type 2' Diabetic Group entirely UNdrugTREATED for 'glucose-lowering'], that has ever been produced, that has ever evidenced that type 2 Diabetics are less healthy UNdrugTREATED for 'glucose-lowering'?

THEN if/when such a document is EVER produced (?) ... PLEASE ask 15 bright INDEPENDENT scientific/judicial Minds to analytically review the REASONing behind the lack of a 'type 2' Diabetic Group entirely UNdrugTREATED for 'glucose-lowering' ... The ANSWER to this challenge will answer Scott's question AND provide the "how" solution requested. You have my word on that.

DIETARY TREATMENT...

HYPERglycemia aka excess blood glucose aka excess blood carbohydrate ... is a symptom of indigestion [especially in respect of the liver].

There is ZERO requirement for any carbohydrate by Human Beings.

UNdrugTREATED type 2 Diabetics can handle plenty of carbohydrate ... They need to drink more WATER because they 'handle' excess carbohydrate simply by urinating excess glucose [water-soluble] just like People urinate excess water-soluble vitamins.

UNdrugTREATED type 2 Diabetics and other healthy People should test daily with ChemStrips and pause from eating, and drink just water, until their urine is glucose free. The less carbohydrate eaten ... the less time between meals.
... 2007 http://tinyurl.com/3b95sl [LoveDiabetes.com]

That is how to CURE more than 20,790,000 Diabetics and prevent all 'newly diagnosed' type 1a, type1b & type 2 diabetes.

Eating less is profoundly different from eating less OFTEN.
... 2000 http://tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
... 2001 http://tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
... 2003 http://tinyurl.com/ys63gk [anson@jhu.edu]
... 2007 http://tinyurl.com/3aypqg [mristow@mristow.org]
... 2007 http://tinyurl.com/29kvda [zangend@hadassah.org.il]

In respect of the opinions above ... please AnyOne ... ALSO ask your current Specialist for advice including the provision of supporting Peer reviewed references evidencing their understanding of this important matter.
... 2007 http://tinyurl.com/2vp4e9 [DrBernarr@aol.com]

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 21:27hrs FRI.14.DEC.2007.

www.DiabetesHealth.com/read/2007/12/03/5558.html
www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]
www.DiabetesHealth.com/read/2007/11/29/5564.html
... 2007 http://en.wikipedia.org/wiki/Hyperglycemia
www.DiabetesHealth.com/read/2007/12/13/5587.html
www.DiabetesHealth.com/read/2007/12/13/5582.html
... 2007 http://tinyurl.com/ywnrs6 [diabetescare@diabetes.org]
... 2007 http://en.wikipedia.org/wiki/Etiology
... 2003 http://tinyurl.com/38x7xr [WhiteHouse.gov ]
... 2007 http://tinyurl.com/2dw2q2 [LoveDiabetes.com]
... 2007 http://tinyurl.com/2arzxs [DiabetesCaseStudy.com]
www.DiabetesHealth.com/read/2007/11/02/5548.html
... 2007 http://en.wikipedia.org/wiki/C-peptide
... 2007 http://tinyurl.com/3bcr7h [LoveDiabetes.com]
... 2007 www.aapsonline.org/ethics/oaths.htm [AAPSonline.org]
... 2006 http://tinyurl.com/2gtyp4 [Roy_Poses@Brown.EDU]
... 2007 http://en.wikipedia.org/wiki/Euthanasia
... 1950 http://tinyurl.com/345uzh [TIME.com]
... 2007 http://tinyurl.com/3xv8y2 [lsn@lifesite.net]
... 1987 http://tinyurl.com/2d48d5 [juangrun@mail.med.upenn.edu]
... 1997 http://tinyurl.com/34lyyj [lobnig@med.uni-duesseldorf.de ]
... 2007 http://en.wikipedia.org/wiki/Anti-diabetic_drug
... 2000 http://tinyurl.com/2j7p3t [ dfadool@neuro.fsu.edu]
... 2001 http://tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
... 2003 http://tinyurl.com/ys63gk [anson@jhu.edu]
... 2007 http://tinyurl.com/3aypqg [mristow@mristow.org]
... 2007 http://tinyurl.com/29kvda [zangend@hadassah.org.il]
... 2007 http://tinyurl.com/2vp4e9 [DrBernarr@aol.com]

Posted by Nicholas Dynes Gracey on 15 December 2007

Posted by bird54 on 15 December 2007:-

"...Have you thought about writing a book explaining your theory and cure for diabetes?..."

Hi bird54 ...

Yes.

But how interested is AnyOne in 'curing' Themselves and/or how interested is any Doctor in providing their Patients with an UNdrugTREATED cure? For example ... The CAUSE of type 1 & type 2 diabetes is known. The CURE for type 1 & type 2 diabetes is relatively straight-forward and is available right now ... UNdrugTREATED and for free c/o
... www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]

What (?) would my writing a book add to what Dr Bernarr is already offering RIGHT NOW ... ie a 100% bona-fide cure for type 1 & type 2 diabetes.

How is your understanding of my work different from your understanding of Dr Bernarr's work?

Joy Pape says: "...we have almost 21 million people with diabetes but only about 15,000 CDEs..."
... www.DiabetesHealth.com/read/2007/12/13/5582.html

bird54 ... please comment on this ... 21 million People with an alleged disease ALL of who could be CURED ... ie in a matter of days be sustainably UNdrugTREATED and super healthy ... for free c/o
... www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]

There is something 'Alice in Wonderland Matrix' about the 'diabetes world' at the present time.
... 1865 http://tinyurl.com/28g4ey [Alice's bottle & cake]
... 2007 http://en.wikipedia.org/wiki/Bluepill
... 1999 http://www.youtube.com/watch?v=0_8Zq_iWuFg

Too many Doctors, who eat too often, prescribing 'drugs' called 'drink me / eat me'; More than 21 million Diabetics, who eat too often, choosing to swallow 'the blue ones'; and a website where the CURE is available RIGHT now ... and ZERO apparent publication yet from Lee Iacocca of his considering Dr Bernarr's CURE for type 1 diabetes ... even though Lee is apparently genuinely seeking the cure for type 1 diabetes.
... 2005 http://www.iacoccafoundation.org [info@iacoccafoundation.org]

Please help with an explanation / understanding? Curing brain-cloud & diabetes is relatively EASY ... but understanding why it is taking so long to accept the CURE that is already available, as above, is a more challenging rabbit hole.
... 1997 http://www.youtube.com/watch?v=oGLKnAvzlg4

In respect of the opinions above ... please AnyOne ... ALSO ask your current Specialist for advice including the provision of supporting Peer reviewed references evidencing their understanding of this important matter.
... 2007 http://tinyurl.com/2vp4e9 [DrBernarr@aol.com]

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 23:32hrs SAT.15.DEC.2007.

www.DiabetesHealth.com/read/2007/12/03/5558.html
www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]
www.DiabetesHealth.com/read/2007/11/29/5564.html
... 2007 http://en.wikipedia.org/wiki/Hyperglycemia
... 2007 http://tinyurl.com/2vp4e9 [DrBernarr@aol.com]
www.DiabetesHealth.com/read/2007/12/13/5582.html
www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]
... 1865 http://tinyurl.com/28g4ey [Alice's bottle & cake]
... 2007 http://en.wikipedia.org/wiki/Bluepill
... 1999 http://www.youtube.com/watch?v=0_8Zq_iWuFg
... 2005 http://www.iacoccafoundation.org [info@iacoccafoundation.org]
... 1997 http://www.youtube.com/watch?v=oGLKnAvzlg4
... 2007 http://tinyurl.com/2vp4e9 [DrBernarr@aol.com]

Posted by bird54 on 16 December 2007

Hi Nick,
You said, "What (?) would my writing a book add to what Dr Bernarr is already offering RIGHT NOW ... ie a 100% bona-fide cure for type 1 & type 2 diabetes."

I think that a book, explaining all the research to back the claims would seem more credible to anyone who would want the scientific basis for the cure to diabetes.

You said, "How is your understanding of my work different from your understanding of Dr Bernarr's work?"

Dr. Bernarr's website says, "Fast only when you are symptomatic, i.e., when you have symptoms. Eat only when you are genuinely hungry....When you fast, drink only water, lie down and close your eyes. Keep your eyes closed every moment of the 24 hours, every day that you water fast. During a water fast, you must have total physiological rest."

That seems a lot different than eating less OFTEN, as you propose. You imply that a person should eat only one meal a day, to give time for complete digestion, and to allow time for the urine to become glucose-free, before consuming another meal. If, as Dr. Bernarr suggests, a person should rest completely with the eyes closed, that could only be accomplished when one is not working. I have been fasting all day while working, and eating when I get home. I have been ignoring my hunger pangs during the day. I never have glucose in my urine, even after a meal, so what would be the benefit for me to fast, except to cleanse my body, reduce the inflammation, and lose excess body fat?

Dr. Bernarr suggests fasting as a cure to all diseases, not just diabetes. The Bible says, "WHEN you fast", not IF you fast, so it was common practice 2000 years ago for people to fast, whereas nowadays health care practitioners say, "Eat small meals more often, and make sure you eat a nutritious breakfast..."

Dr. Bernarr also suggest strenuous anaeorbic exercises to build muscle because glucose in stored in muscle.

I think that Dr. Bernarr's cure for diabetes is very simple and straighforward. However, I think that many people want more scientific basis for a cure.

How much more simple can "eat right and exercise" be? Yet, people refuse to do it. They would rather take drugs. Sad, huh?

Posted by bird54 on 16 December 2007

Hi Nick,
Okay, Here is my response to the following:
Posted by Scott King on 13 December 2007:-

"... How Can We Stop the CRISIS in Diabetes Education? Tell Us How!
... www.DiabetesHealth.com/read/2007/12/13/5587.html

Hi Amy Tenderich,
I agree that there is a "Crisis in Diabetes Education", but for different reasons. Joy Pape recently recommended your article saying, "It used to be so easy to teach people what diabetes is and how to manage it. But the truth is, we just didn't know how much we still don't know. Once again, we need to change our teaching materials about what diabetes is, what causes it, and how to treat it."

I wonder...if it used to be so "easy" to treat diabetes, then what has changed? Is it that we really know "more" than we did before, or is it that we have overlooked the obvious?
Diabetics are told by their physicians that they have a "disease." And of course, a disease needs to be "treated." And since "...we have almost 21 million people with diabetes but only about 15,000 CDEs..." we assume that the answer is that we need more CDEs to treat this epidemic.

The answer may not be that we need more CDEs, but that we need to look at diabetes in a new way. We assume that diabetes is a disease because we are told by our physicians that it is. What if diabetes is not a disease at all, but a natural and normal response to an overabundance of food? Look at the Pima Indians. They have the highest rate of diabetes and morbid obesity in the world. Yet, their ancestors, with the same genes, were healthy and lean. Their "thrifty" genes served them well during times of famine and drought. When food was plentiful, they gained weight. When food was scarce, they lost weight. People in the past moved in and out of diabetes as their food supply increased and diminished. Our bodies are programmed to store fat in anticipation of famines. Our problem is that we live in a time where there is an abundance of food. We cannot continue to eat as if we are preparing for a famine.

Most diabetics consume more calories than they burn. They continue to overeat, thereby feeding their own fat cells, which in the past would have benefited them. Today, without a famine to put a lid on the weight-gain, they continue to gain. Many take drugs and insulin to force feed the cells which are already overloaded. Some resort to stomach bypass surgery to force themselves to eat less. Are we living in the Dark Ages? Do people need to chop out their stomachs in order to reverse their diabetes? That's insanity!

What if diabetes is not a disease at all, but a normal response to an overabundance of food? What if the cure is so simple, that we, in all of our knowledge have overlooked it? What if the answer really is "easy"? What if the cure to diabetes is to eat less often? What if diabetics could cure their diabetes by intermittent fasting? What if people could reverse their diabetes by drinking only fresh water as meal replacements, and eating only when they were hungry, instead of overeating because they are told by their health care practitioners, "Never skip a meal. Always eat breakfast. Eat many small balanced meals throughout the day." So they do that, and they watch themselves get fatter and fatter. Then they wonder, "How did I get diabetes? I followed all the rules!"

Diabetes is not a disease. It is a natural response to an overabundance of food. If you want to cure your diabetes, just eat less often and fast regularly. Don't wait for a famine to cure you, make your own famine!

Posted by Nicholas Dynes Gracey on 16 December 2007

Posted by anonymous on 29 November 2007:-

"... I gained over 5 pounds in a week ... doubled the metformin ... now I am anemic which seems to be raising my bs ..."
... www.DiabetesHealth.com/read/2007/11/29/5564.html

Hi Seale Harris, Martin Buehler, Harry Salzer, Robert Tanenberg, anonymous, AllieB2, ricklude, Allison Love Beatty, Melody, Brent, Billy Warhol, Scott, BetterCell, Glenn, Jenny, David Beatty, bird54, Ladybird, Nick Trubov, Ron Rosedale, Diana Karaffa, Lissa Coffey, John Manley, Bill Corey, MEC, Harry Thompson, Nicholas Rheinberg, Brian Rodgers, Scott King, Linda von Wartburg, Nadia Al-Samarrie, Marianne Henricsson, Michael Ristow, Michael Anson, Toshio Maeda, Paul Tubiana, Bernarr Zovluck, Suzanne de la Monte, Debra Ann Fadool, Ricardo Branco, Matthew Sadgrove, Paul Clayton, Trevor Gunn, Lee Iacocca, Uffe Ravnskov, Anthony Colpo, Shane Ellison, Duane Graveline, Malcolm Kendrick, Joel Fuhrman, Byron Richards, Joel Kauffman, Jerrold Olefsky, Martin Rutter, Bernard Zinman, Saul Malozowski, David Zangen, Eva Feldman, Gail Owen, Philip Cryer, Alan Dyer, Robert Turner, Rury Holman, Ernst Chantelau, Eva Kohner, Venkat Narayan, Jonathan Levy, Trayana Djarova, Sarimari Tupola, Peter Butler, Dr Aulakh, Juan Grunwald, Maurizio Vanelli, Francesca Messina, Ben Bloom, Stefan Herget-Rosenthal, Mariana Ruiz Villarreal & AnyOne else...

Please help expose the CAUSE [etiology] of anonymous' suddenly ... 'gaining 5lbs weight in a week' ... 'becoming anemic' ... 'becoming increasingly HYPERglycemic'.

Hi anonymous ...

WHY

Why the weight gain ?

Why the anemia ??

Why the rise in plasma blood glucose [PBG] following anemia / 'metformin failure' ???

Where's the evidence the weight gain & anemia is an improvement over above-average plasma blood glucose [PBG] and drinking more water when thirsty [to aid urination of excess glucose] ????

Why ... 'chose' to pump excess glucose into body tissues rather than urinate it away with the help of extra water drinking ... WHY ?????

METFORMIN 'RAISES GAS GUZZLING [SPENDING]'...

Pancreatic Glucose Insulin Resistance [GIR] is good. GIR is like having a surge protector on your PC [or an auto-motive gas regulator to prevent inefficient fuel combustion]. When the big glucose meal/flood arrives ... the GIR / surge protector PROTECTS.
... 2007 http://en.wikipedia.org/wiki/Hyperglycemia
... 2007 http://en.wikipedia.org/wiki/Surge_protector
... 2007 http://en.wikipedia.org/wiki/Thames_barrier

Metformin reduces GIR ... glucose is 'sucked' into the peripheral tissues and 'burnt' into lactic acid [like gas is burnt ... aka 'spent' ... in an increasingly inefficient mix and poisonous exhaust gases are produced] allowing PBG to fall too rapidly [relative-HYPOglycemia] as glucose flooding into the peripheral tissues is converted into a build-up of lactic acid waste ... leading to many negative side-effects including anemia.
... 2007 http://en.wikipedia.org/wiki/Lactic_acidosis
... 2007 http://en.wikipedia.org/wiki/Metformin
... 2007 http://en.wikipedia.org/wiki/Gas-guzzler

METFORMIN 'SHUTS DOWN GAS RESERVE-TANK [SAVINGS]'...

An UNdrugTREATED 'type 2' body maintains an above-average blood glucose eg via release from the liver's reserve-tank of glucose ... to prevent nerve/brain damage which happens when certain food/drug combinations cause plasma blood glucose [PBG] too fall too quickly ie the body is protecting nerve/brain cells from the consequences of "relative-HYPOglycemia" [first recognized in 1924]...
... 1924 Harris. S, "Hyperinsulinism and Dysinsulinism", J.A.M.A 83: 729-733, 1924 [Seale Harris]

An awareness of anemia is associated with PBG dropping too fast 'relative' to its starting point eg 360mg suddenly dropping to 180 mg/dl because of too little surge protection ... too little pancreatic GIR ... and too little corrective release of glucose from the liver's reserve-tank of glucose. You 'adaptively' became an UNdrugTREATED type 2 Diabetic as: (a) your body strengthened its pancreatic GIR [aka pancreatic insulin resistance ... which is always beneficial]; and (b) strengthened & built-up power in your liver's reserve-tank of glucose [aka your 'savings' ... which is always beneficial] ... both to help prevent sudden falls in PBG [and thereby protect your nerve/brain tissue from sudden shut down .

In the absence of metformin your liver produces more blood glucose more often to help protect against a sudden fall in PBG.

SUDDEN ANEMIA EXPLAINED...

Here's an example of a proposed mechanism of how pancreatic GIR protects UNdrugTREATED Diabetics from relative-HYPOglycemia and thereby protects against strokes & heart attacks...

Following the introduction of commercial insulin in 1923 ... in 1924 both 'relative-HYPOglycemia' and BIG stroke / heart attack inducing blood clots became 'mortuary news'.
... 2006 http://tinyurl.com/2h68by [benbloom@mail.com]
... 2003 http://tinyurl.com/2owwsn [skarch@sonic.net]

Anemia is often produced as a result of 'exploding' red blood cells [RBC] and/or 'exploding' arterial lining-cells [ALC] and/or 'exploding' beta-cells ... following relative-HYPOglycemia which is a chemistry issue called ... OSMOSIS ... plasma blood glucose [PBG] falls faster than [intracellular RBC & ALC glucose] following HYPOglycemic drug/food/chemical distress ... 'WATER-bomb' RBC & 'WATER-zit' ALC 'explode' [aka hemolysis] during osmotic surge of water into the cells ie causing RBC & ALC edema leading to anemia and in severe cases of rapid PBG reduction ... fragmented ALC and/or fragmented RBC = circulating 'embolic' clot material = infarction and/or 'thrombus' @ ALC 'explosion' site.
... 2007 http://tinyurl.com/2hm3ej ['WATER-bomb' RBC]
... 2007 http://tinyurl.com/39xwhg [HYPOglycemic > HYPOtonic]
... 2007 http://tinyurl.com/25tm3g [Why OSMOSIS]
... 2007 http://en.wikipedia.org/wiki/Hemolysis
... 2007 http://en.wikipedia.org/wiki/Ischemia
... 2007 http://en.wikipedia.org/wiki/Embolic
... 2007 http://en.wikipedia.org/wiki/Thrombus
... 2007 http://en.wikipedia.org/wiki/Infarction

SUDDEN WEIGHT GAIN EXPLAINED...

Sudden weight gain is often caused by the same osmotic correction ... following relative-HYPOglycemia. PBG falls too quickly leaving the concentration of glucose relatively higher in the surrounding interstitial & peripheral tissue and water rushes in by osmosis to correct the imbalance in the glucose concentration leading to a substantial increase in "Peripheral Tissue Glucose" [PTG] concentration.

You may than cut back on food intake only to find your PBG rising suddenly again as glucose is released from your body tissues when your PBG drops lower than your PTG ... even though You are eating less. The PTG is being protectively shed from your tissues into the bloodstream ... raising your PBG with a view to urinating the excess rather than swelling-up your body like a 'water-balloon'.

Such 'water-logging' weight gain ... can also lead to nerve/brain edema and/or the heart failure 'heart-overloading' tissue edema mechanism as PBG falls faster than interstitial fluid / cerebro-spinal fluid PTG ... WATER is osmotically 'pumped' into the interstitial fluid / cerebro-spinal fluid & peripheral tissues ... over-loading the heart's capacity to overcome the extra RESISTANCE from the WATER-logged body ... leading to 'heart-failure'.
... 2007 http://en.wikipedia.org/wiki/Osmosis
... 2007 http://en.wikipedia.org/wiki/Interstitial_fluid
... 2007 http://en.wikipedia.org/wiki/Edema
... 2007 http://en.wikipedia.org/wiki/Bilge_pump
... 2007 http://en.wikipedia.org/wiki/Heart_failure

COMMENTS...

Any comment/s ... upon the possible mechanistic association between infarctions, 'sudden hemolytic anemia' & 'sudden localised weight-gain-edema' following relative-HYPOglycemia associated distress [eg including GM insulin induced' vasoCONSTRICTION'] ... would be appreciated.
... 1987 http://tinyurl.com/2d48d5 [juangrun@mail.med.upenn.edu]

Please review this with my WED.12.DEC.2007 comment [above], in reply to another anonymous 29 November 2007 comment ... including linked references within that reply.

EVIDENCE...

Evidence suggests that being ANYdrugTREATED to reduce plasma blood glucose [PBG] is VERY harmful to type 2 Diabetics ... for example ...

'... Why some cases of retinopathy worsen when diabetic control improves ... the rate of fall of blood glucose concentration and the accompanying reduction in blood flow have been thought to be the trigger ... This suggestion was supported by the finding of Grunwald et al, who showed a 20% reduction of blood flow when blood glucose concentrations fell from about 15 mmol/l to 8 mmol/l.'
... 1987 http://tinyurl.com/2d48d5 [juangrun@mail.med.upenn.edu]
... 1997 http://tinyurl.com/34lyyj [lobnig@med.uni-duesseldorf.de]

As compared with the relative HIGH / JOY of UNdrugTREATED type 2 diabetes and transient supranormal glycemia [TSG].

DIETARY TREATMENT...

Dietary treatment is possible and desirable because HYPERglycemia aka excess blood glucose aka excess blood carbohydrate ... is a symptom of indigestion [especially in respect of the liver].

There is ZERO requirement for any carbohydrate by Human Beings.

UNdrugTREATED type 2 Diabetics can handle plenty of carbohydrate ... They need to drink more WATER because they 'handle' excess carbohydrate simply by urinating excess glucose [water-soluble] just like People urinate excess water-soluble vitamins.

UNdrugTREATED type 2 Diabetics and other healthy People should test daily with ChemStrips and pause from eating, and drink just water, until their urine is glucose free. The less carbohydrate eaten ... the less time between meals.
... 2007 http://tinyurl.com/3b95sl [LoveDiabetes.com]

That is how to CURE type 2 diabetes.

Eating less is profoundly different from eating less OFTEN.
... 2000 http://tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
... 2001 http://tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
... 2003 http://tinyurl.com/ys63gk [anson@jhu.edu]
... 2007 http://tinyurl.com/3aypqg [mristow@mristow.org]
... 2007 http://tinyurl.com/29kvda [zangend@hadassah.org.il]

In respect of the opinions above ... please AnyOne ... ALSO ask your current Specialist for advice including the provision of supporting Peer reviewed references evidencing their understanding of this important matter.
... 2007 http://tinyurl.com/2vp4e9 [DrBernarr@aol.com]

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 19:14hrs SUN.16.DEC.2007.

www.DiabetesHealth.com/read/2007/12/03/5558.html
www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]
www.DiabetesHealth.com/read/2007/11/29/5564.html
... 2007 http://en.wikipedia.org/wiki/Hyperglycemia
... 2007 http://en.wikipedia.org/wiki/Lactic_acidosis
... 2007 http://en.wikipedia.org/wiki/Metformin
... 2007 http://en.wikipedia.org/wiki/Gas-guzzler
... 2006 http://tinyurl.com/2h68by [benbloom@mail.com]
... 2003 http://tinyurl.com/2owwsn [skarch@sonic.net]
... 2007 http://tinyurl.com/2hm3ej ['WATER-bomb' RBC]
... 2007 http://tinyurl.com/39xwhg [HYPOglycemic > HYPOtonic]
... 2007 http://tinyurl.com/25tm3g [Why OSMOSIS]
... 2007 http://en.wikipedia.org/wiki/Hemolysis
... 2007 http://en.wikipedia.org/wiki/Ischemia
... 2007 http://en.wikipedia.org/wiki/Embolic
... 2007 http://en.wikipedia.org/wiki/Thrombus
... 2007 http://en.wikipedia.org/wiki/Infarction
... 2007 http://en.wikipedia.org/wiki/Osmosis
... 2007 http://en.wikipedia.org/wiki/Interstitial_fluid
... 2007 http://en.wikipedia.org/wiki/Edema
... 2007 http://en.wikipedia.org/wiki/Bilge_pump
... 2007 http://en.wikipedia.org/wiki/Heart_failure
www.DiabetesHealth.com/read/2007/12/13/5587.html
www.DiabetesHealth.com/read/2007/12/13/5582.html
... 2007 http://en.wikipedia.org/wiki/The_Optimal_Diet
... 2007 http://tinyurl.com/3buzxn [Suzanne_DeLaMonte_MD@Brown.edu]
... 2006 http://tinyurl.com/2sphx5 [Suzanne_DeLaMonte_MD@Brown.edu]
... 2005 http://tinyurl.com/98bf2 [Suzanne_DeLaMonte_MD@Brown.edu]
... 2005 http://tinyurl.com/2e48a7 [Suzanne_DeLaMonte_MD@Brown.edu]
... 2000 http://tinyurl.com/27ywpz [http://tinyurl.com/327xcl]
... 2007 http://tinyurl.com/ywnrs6 [diabetescare@diabetes.org]
... 2007 http://en.wikipedia.org/wiki/Etiology
... 2003 http://tinyurl.com/38x7xr [WhiteHouse.gov]
... 2007 http://tinyurl.com/2dw2q2 [LoveDiabetes.com]
... 2007 http://tinyurl.com/2arzxs [DiabetesCaseStudy.com]
www.DiabetesHealth.com/read/2007/11/02/5548.html
... 2007 http://en.wikipedia.org/wiki/C-peptide
... 2007 http://tinyurl.com/3bcr7h [LoveDiabetes.com]
... 2007 www.aapsonline.org/ethics/oaths.htm [AAPSonline.org]
... 2006 http://tinyurl.com/2gtyp4 [Roy_Poses@Brown.EDU]
... 2007 http://en.wikipedia.org/wiki/Euthanasia
... 1950 http://tinyurl.com/345uzh [TIME.com]
... 2007 http://tinyurl.com/3xv8y2 [lsn@lifesite.net]
... 2000 http://tinyurl.com/2dad25 [Kauffman@hslc.org]
... 2007 http://tinyurl.com/2jphjr [rob.butler@uhns.nhs.uk]
... 2007 http://tinyurl.com/2c3yj8 [malcolm@llp.org.uk]
... 2007 http://tinyurl.com/2tt8ho [healthexpert]
... 2007 http://tinyurl.com/2jlt7v [funniinnit]
... 2007 http://tinyurl.com/yqmqnj [Kauffman@hslc.org]
... 2006 http://tinyurl.com/nx2bk [BBC.co.uk]
... 2003 http://www.thincs.org/ [ravnskov@tele2.se]
... 1987 http://tinyurl.com/2d48d5 [juangrun@mail.med.upenn.edu]
... 1997 http://tinyurl.com/34lyyj [lobnig@med.uni-duesseldorf.de ]
... 2007 http://en.wikipedia.org/wiki/Anti-diabetic_drug
... 2000 http://tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
... 2001 http://tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
... 2003 http://tinyurl.com/ys63gk [anson@jhu.edu]
... 2007 http://tinyurl.com/3aypqg [mristow@mristow.org]
... 2007 http://tinyurl.com/29kvda [zangend@hadassah.org.il]
... 2007 http://tinyurl.com/2vp4e9 [DrBernarr@aol.com]

Posted by Nicholas Dynes Gracey on 17 December 2007

Posted by bird54 on 16 December 2007:-

"... That seems a lot different than eating less OFTEN, as you propose. You imply that a person should eat only one meal a day, to give time for complete digestion, and to allow time for the urine to become glucose-free, before consuming another meal. If, as Dr. Bernarr suggests, a person should rest completely with the eyes closed, that could only be accomplished when one is not working. I have been fasting all day while working, and eating when I get home. I have been ignoring my hunger pangs during the day. I never have glucose in my urine, even after a meal, so what would be the benefit for me to fast, except to cleanse my body, reduce the inflammation, and lose excess body fat? ..."

... www.DiabetesHealth.com/read/2007/11/29/5564.html

Hi bird54 & Robert Tanenberg ...

ANSWER...

The benefit of fasting more OFTEN would be to become, day by day, even healthier,

QUESTIONS...

1. When [date] was bird54 diagnosed a type 2 Diabetic ?
... 2007 http://en.wikipedia.org/wiki/C-peptide

2. When was bird54's most recent C-peptide test to measure the health of bird54's beta-cells.
... 2007 http://tinyurl.com/2arzxs [DiabetesCaseStudy.com]

3. Why the lack of mention, by Robert Tanenberg, of regular C-peptide tests to evaluate the positive / negative effects of his proposed treatments on his patients' beta-cell function?
... www.DiabetesHealth.com/read/2007/11/29/5564.html

4. Where's the evidence justifying any type 1 or type 2 Diabetic being ANYdrugTREATED when such a Diabetic is able to achieve glucose-free urine by eating less OFTEN?
... 2007 http://en.wikipedia.org/wiki/Anti-diabetic_drug

5. What's bird54's Physician's evidence for any past / future offering of any drugs to bird54?
... 2007 http://tinyurl.com/3bcr7h [LoveDiabetes.com]

ALTERNATIVE MEDICINE FOR DIABETICS...

Eating less is profoundly different from eating less OFTEN.
... 2000 http://tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
... 2001 http://tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
... 2003 http://tinyurl.com/ys63gk [anson@jhu.edu]
... 2007 http://tinyurl.com/3aypqg [mristow@mristow.org]
... 2007 http://tinyurl.com/29kvda [zangend@hadassah.org.il]

Please summarize, in 5 short paragraphs, the most important issue raised in each of the 5 'diabetes breakthrough' references 2000-2007 [listed immediately above].

In respect of ALL the opinions included within this comment ... please AnyOne ... ALSO ask your current Specialist for advice including the provision of supporting Peer reviewed references evidencing their understanding of this important matter.
... 2007 http://tinyurl.com/2vp4e9 [DrBernarr@aol.com]

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 23:57hrs MON.17.DEC.2007 (C) "I-eat-less-OFTEN-I-fast-more-OFTEN".

www.DiabetesHealth.com/read/2007/12/03/5558.html
www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]
www.HealSelf.org/Alzheimer's%20Disease.html
... 2007 http://en.wikipedia.org/wiki/C-peptide
... 2007 http://tinyurl.com/2arzxs [DiabetesCaseStudy.com]
www.DiabetesHealth.com/read/2007/11/29/5564.html
... 2007 http://en.wikipedia.org/wiki/Anti-diabetic_drug
... 2007 http://tinyurl.com/3bcr7h [LoveDiabetes.com]
... 2000 http://tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
... 2001 http://tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
... 2003 http://tinyurl.com/ys63gk [anson@jhu.edu]
... 2007 http://tinyurl.com/3aypqg [mristow@mristow.org]
... 2007 http://tinyurl.com/29kvda [zangend@hadassah.org.il]
... 2007 http://tinyurl.com/2vp4e9 [DrBernarr@aol.com]

Posted by Nicholas Dynes Gracey on 18 December 2007

Posted by Robert Tanenberg on 29 November 2007:-

"... It has been shown that when persons are first diagnosed with type 2 diabetes, they have already lost over fifty percent of their beta cell function ..."

... www.DiabetesHealth.com/read/2007/11/29/5564.html

Hi Robert Tanenberg ...

QUESTION...

What is the evidence reference [Author(s)/journal/year/etc] for your authoritative 'educational' comment on alleged beta-cell status?

WHO wrote the Peer-reviewed references to describe, quantify & evidence the alleged '50% loss of beta-cell function' ?
... PREVIOUS 'beta-cell' question on 29 November 2007

Please provide sufficient information to review the original source of the questionable "IT HAS BEEN SHOWN" alleged authority upon UNdrugTREATED type 2 Diabetic beta-cell function.
... 2003 http://tinyurl.com/2rh6fz [hmdosch@sickkids.ca]
... 2006 http://tinyurl.com/y7znor [hmdosch@sickkids.ca]

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ 23:50hrs TUE.18.DEC.2007 (C) "I-eat-less-OFTEN-I-fast-more-OFTEN".

www.DiabetesHealth.com/read/2007/12/03/5558.html
www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]
www.HealSelf.org/Alzheimer's%20Disease.html
... 2007 http://en.wikipedia.org/wiki/C-peptide
... 2007 http://tinyurl.com/2arzxs [DiabetesCaseStudy.com]
www.DiabetesHealth.com/read/2007/11/29/5564.html
... 2007 http://en.wikipedia.org/wiki/Anti-diabetic_drug
... 2007 http://tinyurl.com/3bcr7h [LoveDiabetes.com]
... PREVIOUS 'beta-cell' question on 29 November 2007
... 2003 http://tinyurl.com/2rh6fz [hmdosch@sickkids.ca]
... 2006 http://tinyurl.com/y7znor [hmdosch@sickkids.ca]
... 2007 http://tinyurl.com/2vp4e9 [DrBernarr@aol.com]

Posted by bird54 on 18 December 2007

Nick said,
"Please summarize, in 5 short paragraphs, the most important issue raised in each of the 5 'diabetes breakthrough' references 2000-2007 [listed immediately above]."

1. Rats that fasted for 72 hr had a reduced plasma insulin level. However, insulin levels in the brain were elevated after a 72 hour fasting period.

2. In mice, hyperglycemia was induced after 48 hours of fasting, but not after 24 hours. Serum insulin levels were low. However, after refeeding for 12 hours, the mice were hyperinsulinimic, insulin resistant and had impaired impaired glucose tolerance. (What is this suggesting--that one should fast no longer than 24 hours?)

3. Intermittent fasting resulted in reduced serum glucose and insulin levels and may protect the brain from disorders such as epilepsy, strokes, Alzheimer's and Parkinson's diseases. Intermittent feeding can enhance health even if the fasting period is followed by a period of overeating.

4. Glucose restriction extends life span of (worms?).

5. Prolonged fasting is safe for type 1 diabetics as long as they reduce their insulin dosage. They had lower insulin levels but higher A1c's (I thought the goal was a lower A1c)

To answer Nick's questions:
1. I was diagnosed with type 2 diabetes in 2005. My fbs was 150 and my A1c was 7.6%
2. I was never given a C-peptide test.
3. My physician told me that I had worn out my beta glands but never did any kind of test to determine the condition of my beta glands.
4. I never had glucose in my urine.
5. Upon diagnosis, I immediately went on a low-carb diet, against my physician's advice, and lowered my A1c to 5.9%, so I was never prescribed any diabetic drugs.
However, in 1990, I had gestational diabetes. They put me on a high carb, low fat diet, which made my diabetes worse. Then I was put on insulin, without a C-peptide test to determine that I needed insulin. I had a bad reaction to insulin. It made my heart race and I felt horrible. When I exercised, I got hypoglycemia. The diabetic nurse told me that my reactions were worse than her "brittle diabetics." They had to keep lowering my dose until I was down to 2 units. Then the physician told me that at that dose, I really didn't need it. When I went into labor, the nurse tried to give me my morning shot of insulin, without even checking my blood sugar, but I refused. I knew that on an empty stomach, and with all that exercise (contractions of labor), I would have gone into insulin shock. I can't believe how ignorant they were. As it was, my baby got stressed, was born with hypoglycemia, and had to be put into ICU for a day.
I don't trust the medical profession any more. They could not prevent my diabetes, even though they knew I was at risk. In fact, one physician told me, "You cannot prevent diabetes. You will get it no matter what you do." Doctors have not given me any good advice about how to treat it. Everything I know about diabetes, I have learned on my own. Whenever I have a check-up, they want to put me on statin drugs and ACE inhibitors. I have more faith in my own body's ability to regulate itself than I do in physicians and prescription drugs.

Posted by bird54 on 18 December 2007

Dr. Tenanburg,
Why do you recommend insulin during pregnancy? On your chart, you listed:

"Indications for Starting Insulin"
"Absolute"
"During pregnancy"

My grandmother had three, fat, healthy babies, all 10 and 12 pounders, with no complications or defects.
My second baby, born in 1993, was a HEALTHY 10 pounds 10 ounces. He was born at 42 weeks. During labor, he showed no signs of distress. His heart rate did not drop during contractions. The nurses kept commenting how much endurance he had. His delivery was natural with no drugs and no epidural. The doctor was surprised to find that he did not have hypoglycemia or a broken collar bone. He was so strong that he could hold his head up. They commented, "This is no newborn--This is a three-month-old!
I'm glad I did not take insulin. My OBGYN did not give me insulin, even though I had glucose in my urine. I just ate healthy foods and exercised.

Posted by bird54 on 18 December 2007

Hi Nick (and anyone else),
What do you think of the science daily article-- http://www.sciencedaily.com:80/releases/2007/12/071217150506.htm--scientists nix low carb diets? They say that ketogenic diets are harmful, yet the research linked in Nick's previous comments on fasting show that ketogenic diets protect the brain. Why the discrepency?

Posted by Nicholas Dynes Gracey on 19 December 2007

ALTERNATIVE MEDICINE FOR DIABETICS...

Eating less OFTEN is profoundly more healthy than eating less...
... 2000 http://tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
... 2001 http://tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
... 2003 http://tinyurl.com/ys63gk [anson@jhu.edu]
... 2007 http://tinyurl.com/ynpp4g [raymond.swanson@ucsf.edu]
... 2007 http://tinyurl.com/29kvda [zangend@hadassah.org.il]
... 2007 http://tinyurl.com/3aypqg [mristow@mristow.org]

Posted by bird54 on 18 December 2007
... www.DiabetesHealth.com/read/2007/11/29/5564.html

Nick said,
"Please summarize, in 5 short paragraphs, the most important issue raised in each of the 5 'diabetes breakthrough' references 2000-2007 [listed immediately above]."

bird54 says...
1. Rats that fasted for 72 hr had a reduced plasma insulin level. However, insulin levels in the brain were elevated after a 72 hour fasting period.
... 2000 http://tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]

Hi bird54 ...

Debra Fadool's 2000 reference may well prove to be one of the MOST influential pieces of research ever done, so far, in the field of dementia / depression / Alzheimer's / 'diabetes' [aka above average plasma blood glucose].
"...Our data suggest that there is a clear differential between the levels of insulin in the plasma and that found in the... " brain/nerve tissue.

A) Why do You think that the brain may selectively increase manufacture of more brain/nerve insulin [BNI] at times when pancreatic beta-cell insulin [PBI] manufacture is simultaneously reduced ? And would an increase in peripheral tissue 'Glucose Insulin Resistance' [GIR aka inflammation] help or hinder that adaptation?
... [CLUE = surface irrigation systems eg still adopted efficiently in Africa]
... 2007 http://en.wikipedia.org/wiki/Irrigation

B) If the BNI production multiplication factor of increased brain/nerve insulin at 72 hours is 15 x 'times' greater ... what do You speculate it is at 3 / 6 / 12 / 24 / 48 & 96 hours ?
http://en.wikipedia.org/wiki/Proportionality_(mathematics)

C) What is the probable significance [in relation to the consequences of meal frequency] of the discovery that BNI "levels are low after a meal" as regards the increased EFFICIENCY of glucose fuel availability to brain/nerve tissue of dementia / depression / Alzheimer's [aka type 3 Diabetic] Patients / 'mood-swinging Diabetics' ... who eat less OFTEN ? And under what circumstances would an adaptive increase in brain/nerve tissue 'Glucose Insulin Resistance' [GIR aka inflammation] be expected and for what reason ?
... 2007 http://tinyurl.com/ynpp4g [raymond.swanson@ucsf.edu]
... 2007 http://tinyurl.com/3aypqg [mristow@mristow.org]

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ WED.19.DEC.2007 @ 23:55hrs (C) "I-eat-less-OFTEN-I-fast-more-OFTEN".

... 2000 http://tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
... 2001 http://tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
... 2003 http://tinyurl.com/ys63gk [anson@jhu.edu]
... 2007 http://tinyurl.com/ynpp4g [raymond.swanson@ucsf.edu]
... 2007 http://tinyurl.com/29kvda [zangend@hadassah.org.il]
... 2007 http://tinyurl.com/3aypqg [mristow@mristow.org]
www.DiabetesHealth.com/read/2007/12/19/5575.html
www.DiabetesHealth.com/read/2007/12/03/5558.html
www.DiabetesHealth.com/read/2007/11/29/5564.html
www.DiabetesHealth.com/read/2007/11/27/5541.html
www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]
... 2007 http://tinyurl.com/282st8 [DrBernarr@aol.com]
... 2007 http://en.wikipedia.org/wiki/C-peptide
... 2007 http://tinyurl.com/2arzxs [DiabetesCaseStudy.com]
... 2007 http://en.wikipedia.org/wiki/Anti-diabetic_drug
... 2007 http://tinyurl.com/3bcr7h [LoveDiabetes.com]
... 2007 http://tinyurl.com/24nktv [LoveDiabetes.com]
... 2007 http://en.wikipedia.org/wiki/Irrigation
... 2007 http://en.wikipedia.org/wiki/Proportionality_(mathematics)
... 2007 http://tinyurl.com/ynpp4g [raymond.swanson@ucsf.edu]
... 2007 http://tinyurl.com/3aypqg [mristow@mristow.org]
... 2007 http://tinyurl.com/2jh8cj [MayoClinic.com]
... 2007 http://tinyurl.com/2vp4e9 [DrBernarr@aol.com]

Posted by Nicholas Dynes Gracey on 20 December 2007

The 'self-care' song CURE for ALL Diabetics ...

"I-eat-less-OFTEN-I-fast-more-OFTEN"

Posted by Linda von Wartburg on 19 December 2007
>www.DiabetesHealth.com/read/2007/12/19/5575.html

Linda von Wartburg says...
"A recent study about the interplay between diabetes self-care and depression surveyed 879 patients with type 2 ... Only 14.2 percent claimed to be free of depressive symptoms.
> 0507 tinyurl.com/2ju5j2 [jsgonzalez@partners.org]

Hi Linda & AnyOne else...

Depending upon the severity of a Person getting a blood glucose "number down" too quickly ... since JAN.1966 [and before] it has been proven that relative-HYPOglycemia can result in the following neuro-psychiatric symptoms as the body is distressed into 'corrective' methods of preventing nerve/brain tissue from switching-off ...

Depression, Insomnia, Anxiety, Irritability, Crying Spells, Phobias, Lack of Concentration, Forgetfulness or Confusion, Unsocial or Antisocial Behavior, Restlessness, Psychosis, Suicidal Behavior; Exhaustion or Fatigue, Sweating, Tachycardia, Anorexia, Chronic Indigestion or Bloating, Cold Hands or Feet, Joint Pains, Obesity, Abdominal Spasm; Headache, Dizziness, Tremor [inward or external], Muscle Pains & Backache, Numbness, Blurred Vision, Muscular Twitching or Cramps, Staggering, Fainting or Blackouts and also Convulsions.
> 0166 'Relative-HYPOglycemia As A Cause Of Neuropsychiatric Illness' @ Journal Of The National Medical Association @ Harry M Salzer MD @ January 1966 @ Vol 58 @ Number 1 @ Table 1 @ Figure 2.

Following the significance of Harry Salzer's 1966 reference ... Debra Fadool's 2000 reference may well prove to be one of the MOST influential pieces of research ever done, so far, in the field of depression / dementia / Alzheimer's / 'diabetes' [aka above average plasma blood glucose].
"...Our data suggest that there is a clear differential between the levels of insulin in the plasma and that found in the... " brain/nerve tissue.
>0400 tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]

EAT-LESS-OFTEN ... MAKE MORE
BRAIN NERVE INSULIN [BNI]

Why do You think that Fadool found that the brain may selectively increase manufacture of more brain/nerve insulin [BNI] at times when pancreatic beta-cell insulin [PBI] manufacture is simultaneously reduced ?
And would an increase in peripheral tissue 'Glucose Insulin Resistance' [GIR aka inflammation] help or hinder that adaption?
... [CLUE = surface irrigation systems eg still adopted efficiently in Africa]
>1207 en.wikipedia.org/wiki/Irrigation

EAT TOO OFTEN TURN-OFF
BRAIN NERVE INSULIN [BNI]

If the BNI production multiplication factor of increased brain/nerve insulin ... by 72 hours of just drinking water ... can be 15 x 'times' BNI greater [Fadool's discovery] ...
... What do You speculate BNI production may be with a snack/meal at 1 / 3 / 6 / 12 / 24 / 48 & 96 hours ?
>1207 en.wikipedia.org/wiki/Proportionality_(mathematics)

MEALS TURN-OFF
BRAIN NERVE INSULIN [BNI]

What is the probable significance [in relation to the consequences of meal frequency] of the discovery that BNI "levels are low after a meal" as regards the increased EFFICIENCY of glucose fuel availability to brain/nerve tissue of depression / dementia / Alzheimer's [aka type 3 Diabetic] Patients / 'mood-swinging Diabetics' ... who eat less OFTEN ?
And under what circumstances would an adaptive increase in brain/nerve tissue 'Glucose Insulin Resistance' [GIR aka inflammation] be expected and for what reason ?
>0407 tinyurl.com/ynpp4g [raymond.swanson@ucsf.edu]
>1007 tinyurl.com/3aypqg [mristow@mristow.org]

REMEMBER THE ONLY REAL EVIDENCE
IS THAT ABOVE AVERAGE 'BLOOD GLUCOSE'
IS HEALTHIER THAN any ARTIFICIAL LOWERING

UNdrugTREATED type 2 Diabetics and other healthy People should test daily with ChemStrips and pause from eating, and drink just water, until their urine is glucose free. The less carbohydrate eaten ... the less time between meals.

That is how to CURE type 2 diabetes and prevent all 'newly diagnosed' type 1 & type 2 diabetes.

In respect of ALL the opinions included within this comment ... please AnyOne ... ALSO ask your current Specialist for advice including the provision of supporting Peer reviewed references evidencing their understanding of this important matter.
>1207 tinyurl.com/2vp4e9 [DrBernarr@aol.com]

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ THU.20.DEC.2007 @ 23:57hrs (C) "I-eat-less-OFTEN-I-fast-more-OFTEN".

Eating less OFTEN is profoundly more healthy than eating less...
>0400 tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
>0501 tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
>0503 tinyurl.com/ys63gk [anson@jhu.edu]
>0407 tinyurl.com/29kvda [zangend@hadassah.org.il]
>1007 tinyurl.com/3aypqg [mristow@mristow.org]
www.DiabetesHealth.com/read/2007/12/19/5575.html
www.DiabetesHealth.com/read/2007/12/03/5558.html
www.DiabetesHealth.com/read/2007/11/29/5564.html
www.DiabetesHealth.com/read/2007/11/27/5541.html
www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]
>1207 tinyurl.com/282st8 [DrBernarr@aol.com]
>1207 en.wikipedia.org/wiki/C-peptide
>1207 en.wikipedia.org/wiki/Anti-diabetic_drug
>1207 tinyurl.com/3bcr7h [LoveDiabetes.com]
>1207 tinyurl.com/24nktv [LoveDiabetes.com]
>1207 en.wikipedia.org/wiki/Irrigation
>1207 en.wikipedia.org/wiki/Proportionality_(mathematics)
>1207 tinyurl.com/2vp4e9 [DrBernarr@aol.com]
>0407 tinyurl.com/ynpp4g [raymond.swanson@ucsf.edu]
>0906 tinyurl.com/2jh8cj [MayoClinic.com]
>0903 tinyurl.com/2owwsn [skarch@sonic.net]
>0103 tinyurl.com/2arzxs [DiabetesCaseStudy.com]
>1197 tinyurl.com/34lyyj [lobnig@med.uni-duesseldorf.de]
>1287 tinyurl.com/2d48d5 [juangrun@mail.med.upenn.edu]
>0166 'Relative-HYPOglycemia As A Cause Of Neuropsychiatric Illness' @ Journal Of The National Medical Association @ Harry M Salzer MD @ January 1966 @ Vol 58 @ Number 1 @ Table 1 @ Figure 2.
>0124 "Hyperinsulinism and Dysinsulinism" @ J.A.M.A @ Seale Harris @ 1924 @ Vol 83 @ page 729-733.

Posted by bird54 on 21 December 2007

To Nick and anyone else,

Nick's "I-eat-less-OFTEN-I-fast-more-OFTEN" method really does work.
I lost 10 pounds in 2 weeks!
They all say, "Lose weight (if you can) and your diabetes will go away." Easier said than done. I tried low carbs and exercise, but it didn't take off the pounds like "eating-less-often-fasting-more-often."

Posted by Nicholas Dynes Gracey on 21 December 2007

The 'self-care' song CURE for ALL Diabetics ...

"I-eat-less-OFTEN-
I-fast-more-OFTEN"

Posted by bird54 on 18 December 2007
> www.DiabetesHealth.com/read/2007/11/29/5564.html

bird54 says...
"Hi Nick (and anyone else),
What do you think of the science daily article -- http://www.sciencedaily.com:80/releases/2007/12/071217150506.htm -- scientists nix low carb diets? They say that ketogenic diets are harmful, yet the research linked in Nick's previous comments on fasting show that ketogenic diets protect the brain. Why the discrepancy?
> 1207 tinyurl.com/3x9qh6
> 1207 tinyurl.com/29udcr
> 0904 tinyurl.com/7ggyq

Hi bird54 & AnyOne else...

Carol Johnston found a higher percentage of calcium in the urine which may be associated with the beneficial effects of ketogenic diets and their possible reduction of calcification of tissues associated with aging disease. Calcium homeostasis is far more important than the 'bone issue' focussed upon by the science daily article.
> 1006 tinyurl.com/2hnp9h
> 0906 tinyurl.com/yuqqes
> 0202 tinyurl.com/2rhf7p

The upside of a low carbohydrate intake, especially sub15%, is that Dieters usually go into what's called ketosis, or the increased efficiency of the body to oxidize fat aka 'white adipose tissue'.
> 1207 en.wikipedia.org/wiki/Ketosis
> 1106 tinyurl.com/2bn2g7
> 1203 tinyurl.com/39zu9o
> 0503 tinyurl.com/ys63gk

Carol also found the ketogenic diets were capable of raising cholesterol levels which is associated with substantially improved cardiovascular health.
> 0607 tinyurl.com/2v2pyx

ONE MEAL A DAY

By repeatedly singing the 'self-care' song ... "I-eat-less-OFTEN-I-fast-more-OFTEN" it is possible to train the subconscious to enjoy 1 meal a day [or less] and train the body's metabolism to enter into ketosis increasingly quickly. By fuelling the body increasingly on ketones the LIVER can better focus upon gluconeogenesis for supplying an efficient flow of glucose to the brain during especially during times of stress & distress.
> 1207 en.wikipedia.org/wiki/Gluconeogenesis

Ketogenic diets, like 1 meal a day, can help avoid the severity of a Person getting a blood glucose "number down" too quickly ... which is very beneficial ... because ... since JAN.1966 [and before] it has been proven that relative-HYPOglycemia can result in the following neuro-psychiatric symptoms as the body is distressed into 'corrective' methods of preventing nerve/brain tissue from switching-off ...

Depression, Insomnia, Anxiety, Irritability, Crying Spells, Phobias, Lack of Concentration, Forgetfulness or Confusion, Unsocial or Antisocial Behavior, Restlessness, Psychosis, Suicidal Behavior; Exhaustion or Fatigue, Sweating, Tachycardia, Anorexia, Chronic Indigestion or Bloating, Cold Hands or Feet, Joint Pains, Obesity, Abdominal Spasm; Headache, Dizziness, Tremor [inward or external], Muscle Pains & Backache, Numbness, Blurred Vision, Muscular Twitching or Cramps, Staggering, Fainting or Blackouts and also Convulsions.
> 0166 'Relative-HYPOglycemia As A Cause Of Neuropsychiatric Illness' @ Journal Of The National Medical Association @ Harry M Salzer MD @ January 1966 @ Vol 58 @ Number 1 @ Table 1 @ Figure 2.

MORE EVIDENCE...

' ... Because the cerebral glucose concentration [CGC] approaches zero when plasma glucose concentration [PGC] decreases to below 40 mg/dL, 'blood glucose' PGC should be maintained above this level....'
Evidence suggests that being ANYdrugTREATED to quickly reduce blood plasma glucose concentration [PGC], has negative effects upon [brain/nerve] cerebro-spinal glucose concentration [CGC] ... comparable to giving a deep sea Diver 'the bends' by too physiologically-quick 'an ascent' ... 'the glycemic bends', too physiologically-quick 'a descent', can have very negative effects upon Diabetics ...
> 1203 tinyurl.com/39zu9o
> 0704 tinyurl.com/2xx6ps
> 0993 tinyurl.com/2xbcs8
> 0178 tinyurl.com/33q5rt

'... Why some cases of retinopathy worsen when diabetic control improves ... the rate of fall of blood glucose concentration and the accompanying reduction in blood flow have been thought to be the trigger ... This suggestion was supported by the finding of Grunwald et al, who showed a 20% reduction of blood flow when blood glucose concentrations fell from about 15 mmol/l to 8 mmol/l ... This "normo-glycemic re-entry phenomenon" has puzzled clinicians ... and ... there is still much to learn about its mechanism ...'
> 1087 tinyurl.com/2d48d5
> 1097 tinyurl.com/34lyyj

'... 3867 newly diagnosed patients with type 2 diabetes, median age 54 years [48–60 years], who after 3 months' diet treatment had a mean of two fasting plasma glucose [FPG] concentrations of 6·1–15·0 mmol/L, were randomly assigned 'intensive policy' with a sulphonylurea [chlorpropamide, glibenclamide, or glipizide] or with insulin, or 'conventional policy' with diet. The aim in the intensive group was FPG less than 6 mmol/L. In the conventional group, the aim was the best achievable FPG with diet alone; HYPOglycemic drugs were added, to rapidly reduce FPG to 6 mmol/L, only if there were HYPERglycemic symptoms [eg thirst] OR fasting plasma glucose greater than 15 mmol/L...'
> 1098 tinyurl.com/38cr65
> 1207 en.wikipedia.org/wiki/Anti-diabetic_drug

HARRY SALZER & DEBRA FADOOL

Following the significance of Harry Salzer's 1966 breakthrough reference ... Debra Fadool's 2000 reference may well prove to be one of the MOST influential pieces of research ever done, so far, in the field of depression / dementia / Alzheimer's / 'diabetes' [aka above average plasma blood glucose].
"...Our data suggest that there is a clear differential between the levels of insulin in the plasma and that found in the... " brain/nerve tissue.
> 0400 tinyurl.com/2j7p3t

EAT-LESS-OFTEN ... MAKE MORE
BRAIN NERVE INSULIN [BNI]

Why do You think that Fadool found that the brain may selectively increase manufacture of more brain/nerve insulin [BNI] at times when pancreatic beta-cell insulin [PBI] manufacture is simultaneously reduced ?
And would an increase in peripheral tissue 'Glucose Insulin Resistance' [GIR aka inflammation] help or hinder that adaption?
... [CLUE = surface irrigation systems eg still adopted efficiently in Africa]
> 1207 en.wikipedia.org/wiki/Irrigation

EAT TOO OFTEN TURN-OFF
BRAIN NERVE INSULIN [BNI]

If the BNI production multiplication factor of increased brain/nerve insulin ... by 72 hours of just drinking water ... can be 15 x 'times' BNI greater [Fadool's discovery].
... What do You speculate BNI production may be with a snack/meal at 1 / 3 / 6 / 12 / 24 / 48 & 96 hours ?
> 1207 en.wikipedia.org/wiki/Proportionality_(mathematics)

MEALS TURN-OFF
BRAIN NERVE INSULIN [BNI]

What is the probable significance [in relation to the consequences of meal frequency] of Fadool's discovery that BNI "levels are low after a meal" as regards the increased EFFICIENCY of glucose fuel availability to brain/nerve tissue of depression / dementia / Alzheimer's [aka type 3 Diabetic] Patients / 'mood-swinging Diabetics' ... who eat less OFTEN ?
And under what circumstances would an adaptive increase in brain/nerve tissue 'Glucose Insulin Resistance' [GIR aka inflammation] be expected and for what reason ?
> 0407 tinyurl.com/ynpp4g
> 1007 tinyurl.com/3aypqg

REMEMBER THE ONLY REAL EVIDENCE
IS THAT ABOVE AVERAGE 'BLOOD GLUCOSE'
IS HEALTHIER THAN any ARTIFICIAL LOWERING

UNdrugTREATED type 2 Diabetics and other healthy People should test daily with ChemStrips and pause from eating, and drink just water, until their urine is glucose free. The less carbohydrate eaten ... the less time between meals.

That is how to CURE type 2 diabetes and prevent all 'newly diagnosed' type 1 & type 2 diabetes.

In respect of ALL the opinions included within this comment ... please AnyOne ... ALSO ask your current Specialist for advice including the provision of supporting Peer reviewed references evidencing their understanding of this important matter.
> 1207 tinyurl.com/2vp4e9

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ FRI.21.DEC.2007 @ 23:59hrs (C) "I-eat-less-OFTEN-I-fast-more-OFTEN".

Eating less OFTEN is profoundly more healthy than eating less...
> 0400 tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
> 0501 tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
> 0503 tinyurl.com/ys63gk [anson@jhu.edu]
> 0407 tinyurl.com/29kvda [zangend@hadassah.org.il]
> 1007 tinyurl.com/3aypqg [mristow@mristow.org]
www.DiabetesHealth.com/read/2007/12/19/5575.html
www.DiabetesHealth.com/read/2007/12/03/5558.html
www.DiabetesHealth.com/read/2007/11/29/5564.html
www.DiabetesHealth.com/read/2007/11/27/5541.html
www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]
> 1207 tinyurl.com/3x9qh6
> 1207 tinyurl.com/29udcr
> 1207 en.wikipedia.org/wiki/Ketosis
> 1207 en.wikipedia.org/wiki/Gluconeogenesis
> 1207 en.wikipedia.org/wiki/Anti-diabetic_drug
> 1207 tinyurl.com/282st8 [DrBernarr@aol.com]
> 1207 en.wikipedia.org/wiki/C-peptide
> 1207 en.wikipedia.org/wiki/Anti-diabetic_drug
> 1207 tinyurl.com/3bcr7h [LoveDiabetes.com]
> 1207 tinyurl.com/24nktv [LoveDiabetes.com]
> 1207 en.wikipedia.org/wiki/Irrigation
> 1207 en.wikipedia.org/wiki/Proportionality_(mathematics)
> 1207 tinyurl.com/2vp4e9 [DrBernarr@aol.com]
> 0607 tinyurl.com/2v2pyx
> 0407 tinyurl.com/ynpp4g [raymond.swanson@ucsf.edu]
> 1106 tinyurl.com/2bn2g7
> 1006 tinyurl.com/2hnp9h
> 0906 tinyurl.com/yuqqes
> 0906 tinyurl.com/2jh8cj [MayoClinic.com]
> 0904 tinyurl.com/7ggyq
> 0704 tinyurl.com/2xx6ps
> 1203 tinyurl.com/39zu9o
> 0903 tinyurl.com/2owwsn [skarch@sonic.net]
> 0503 tinyurl.com/ys63gk
> 0103 tinyurl.com/2arzxs [DiabetesCaseStudy.com]
> 0202 tinyurl.com/2rhf7p
> 1098 tinyurl.com/38cr65
> 1197 tinyurl.com/34lyyj [lobnig@med.uni-duesseldorf.de]
> 0993 tinyurl.com/2xbcs8
> 1287 tinyurl.com/2d48d5 [juangrun@mail.med.upenn.edu]
> 0178 tinyurl.com/33q5rt
> 0166 'Relative-HYPOglycemia As A Cause Of Neuropsychiatric Illness' @ Journal Of The National Medical Association @ Harry M Salzer MD @ January 1966 @ Vol 58 @ Number 1 @ Table 1 @ Figure 2.
> 0124 "Hyperinsulinism and Dysinsulinism" @ J.A.M.A @ Seale Harris @ 1924 @ Vol 83 @ page 729-733.

Posted by Nicholas Dynes Gracey on 22 December 2007

Sing the 'self-care' song 'CURE' for ALL type 1, type 2, type 3 & type 4 Diabetics ...

"I-eat-less-OFTEN-
I-fast-more-OFTEN"

Posted by bird54 on 21 December 2007
> www.DiabetesHealth.com/read/2007/11/29/5564.html

To Nick and anyone else,

Nick's "I-eat-less-OFTEN-I-fast-more-OFTEN" method really does work.
I lost 10 pounds in 2 weeks!
They all say, "Lose weight (if you can) and your diabetes will go away." Easier said than done. I tried low carbs and exercise, but it didn't take off the pounds like "eating-less-often-fasting-more-often."

Hi bird54 & AnyOne else...
You've studied research & found better AND better findings because You've asked better AND better questions with a genuine desire for better AND better answers...

Your progress is sure, steady & deserved ... "Every day AND in every way You are getting better AND better."

ONE MEAL A DAY

By consciously & repeatedly singing the 'self-care' song ... "I-eat-less-OFTEN-I-fast-more-OFTEN"
... it is increasingly possible, for these lyrics, to train your subconscious mind to better AND better enjoy 1 meal a day [or less] and every day ... train your body's metabolism to enter into 'healing ketosis' increasingly quickly.
> www.en.wikipedia.org/wiki/%C3%89mile_Cou%C3%A9
> www.en.wikipedia.org/wiki/Ketosis

GLUCOSE PRODUCTION ON-DEMAND

By fueling the body, increasingly on ketones, the LIVER can better focus upon gluconeogenesis for supplying an efficient flow of glucose ... out of the liver and into the plasma ... to increase the blood plasma glucose concentration [PGc] ... specifically to help fuel the brain & nerves especially during times of stress & distress.
> www.en.wikipedia.org/wiki/Gluconeogenesis
> 1107 www.tinyurl.com/2u88dx [mattsonm@grc.nia.nih.gov]

KETOGENIC DIETS HELP

Ketogenic diets, like 1 meal a day, can help any Diabetic to gently & naturally, reduce their post-meal glucose concentration [PGc] 'slowly & surely' ... which is very beneficial ... because ... since JAN.1966 [and before] it has been proven that relative-HYPOglycemia can result from 'too quick' a reduction of PGC ... resulting in the following neuro-psychiatric symptoms as the body is distressed into 'corrective' methods of preventing nerve/brain tissue from switching-off and/or 'flickering' from the effects of subsequent ... too rapidly reduced cerebral glucose concentration [CGc] aka brain/nerve 'glucose starvation' aka Neuro-Glycopenia ... aka ... the 'Neuro-Glycemic-bends' [NGb] ...

Depression, Insomnia, Anxiety, Irritability, Crying Spells, Phobias, Lack of Concentration, Forgetfulness or Confusion, Unsocial or Antisocial Behavior, Restlessness, Psychosis, Suicidal Behavior; Exhaustion or Fatigue, Sweating, Tachycardia, Anorexia, Chronic Indigestion or Bloating, Cold Hands or Feet, Joint Pains, Obesity, Abdominal Spasm; Headache, Dizziness, Tremor [inward or external], Muscle Pains & Backache, Numbness, Blurred Vision, Muscular Twitching or Cramps, Staggering, Fainting or Blackouts and also Convulsions.
> 0166 'Relative-HYPOglycemia As A Cause Of Neuropsychiatric Illness' @ Journal Of The National Medical Association @ Harry M Salzer MD @ January 1966 @ Vol 58 @ Number 1 @ Table 1 @ Figure 2.

DIABETES FEEDS your BRAIN

' ... Because the cerebral glucose concentration [CGc] approaches zero when plasma glucose concentration [PGc] decreases to below 40 mg/dL, 'blood glucose' PGc should be maintained above this level....'

Evidence suggests that being ANYdrugTREATED less OFTEN ... better AND better MORE slowly & naturally reduces blood plasma glucose concentration [PGc], having consequential positive effects upon [brain/nerve] cerebro-spinal glucose concentration [CGc] ... comparable to giving a deep sea Diver time to avoid 'the bends' by too physiologically-quick 'an ascent' ... avoiding 'the glycemic bends', too physiologically-quick 'a descent', can have very positive effects upon Diabetics including all manner of relative-HYPOglycemia associated symptoms.
> www.en.wikipedia.org/wiki/Neuroglycopenia
> www.tinyurl.com/23akqw [Relative-HYPOglycemia]
> www.en.wikipedia.org/wiki/Non-epileptic_seizure
> 1203 www.tinyurl.com/39zu9o [Lori A Markham]
> 0704 www.tinyurl.com/2xx6ps [JML@biostat.bsc.gwu.edu]
> 0124 "Hyperinsulinism and Dysinsulinism" @ J.A.M.A @ Seale Harris @ 1924 @ Vol 83 @ page 729-733.

Less OFTEN ANYdrugTREATED
FOR better AND better WEIGHT CONTROL

'... Weight gain was a problem with intensive therapy, with an increase of 33 percent in the mean adjusted risk of becoming overweight, a condition defined as a body weight more than 120 percent above the ideal [12.7 cases of overweight per 100 patient-years in the intensive-therapy group vs. 9.3 in the conventional-therapy group]. At five years, patients receiving intensive therapy had gained a mean of 4.6 kg more than patients receiving conventional therapy...'
> 0993 www.tinyurl.com/2xbcs8 [DCCT 1993]
> 1188 www.tinyurl.com/2mcvz8 [DCCT 1988]
> 0178 www.tinyurl.com/33q5rt [ndic@info.niddk.nih.gov]
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]

Less OFTEN ANYdrugTREATED
FOR better AND better EYES & KIDNEYS

'... Why some cases of retinopathy worsen when diabetic control improves ... the rate of fall of blood glucose concentration and the accompanying reduction in blood flow have been thought to be the trigger ... This suggestion was supported by the finding of Grunwald et al, who showed a 20% reduction of blood flow when blood glucose concentrations fell from about 15 mmol/l to 8 mmol/l ... This "Normo-Glycemic re-entry phenomenon" has puzzled clinicians ... and ... there is still much to learn about its mechanism ...'
> 1087 www.tinyurl.com/2d48d5 [juangrun@mail.med.upenn.edu]
> 0297 www.tinyurl.com/yu77y7 [m.henricsson@telia.com]
> 1097 www.tinyurl.com/34lyyj [lobnig@med.uni-duesseldorf.de]

"NORMO-GLYCEMIC re-entry [NGr] PHENOMENON"

'... 3867 newly diagnosed patients with type 2 diabetes, median age 54 years [48–60 years], who after 3 months' diet treatment had a mean of two fasting plasma glucose [FPGc] concentrations of 6·1–15·0 mmol/L, were randomly assigned 'intensive policy' with a sulphonylurea [chlorpropamide, glibenclamide, or glipizide] or with insulin, or 'conventional policy' with diet. The aim in the intensive group was FPGc less than 6 mmol/L. In the conventional group, the aim was the best achievable FPGc with diet alone; HYPOglycemic drugs were added, to rapidly reduce FPGc to 6 mmol/L, only if there were HYPERglycemic symptoms [eg thirst] OR fasting plasma glucose greater than 15 mmol/L...'
> 1098 www.tinyurl.com/38cr65 [Turner UKPDS 33]
> www.en.wikipedia.org/wiki/Anti-diabetic_drug

HARRY SALZER & DEBRA FADOOL

Following the significance of Harry Salzer's 1966 breakthrough reference ... Debra Fadool's 2000 reference may well prove to be one of the MOST influential pieces of research ever done, so far, in the field of depression / dementia / Alzheimer's / 'diabetes' [aka above average plasma blood glucose].

"...Our data suggest that there is a clear differential between the levels of insulin in the plasma and that found in the..." brain/nerve tissue.
> 0400 www.tinyurl.com/2j7p3t

EAT-less-OFTEN ... MAKE less FAT and/or
WAT STORING beta-cell INSULIN [BCI]

Why do You think that Fadool's 2000 research found that the brain may selectively increase manufacture of more brain/nerve insulin [BNI] at times when pancreatic beta-cell insulin [BCI] manufacture is simultaneously DELIBERATELY reduced ?

And how would an increase in peripheral tissue 'Glucose Insulin Resistance' [GIR aka inflammation] help that DELIBERATE adaption?

CLUE = surface irrigation systems eg still adopted efficiently in Africa.
> www.en.wikipedia.org/wiki/Irrigation
> 0195 www.tinyurl.com/2lb5om [jolefsky@ucsd.edu]
> www.TheDiabetesBlog.com/2007/04/19/no-food-no-problem

FAST-more-OFTEN ... MAKE more BAT and
BRAIN NERVE INSULIN [BNI]

If the BNI production multiplication factor of increased brain/nerve insulin ... by 72 hours of just drinking water ... can be 15 x 'times' BNI greater [Fadool's 2000 discovery].

What do You speculate may happen to 'brain-POWERing' BNI production with a break-fast/snack/meal at 1 / 3 / 6 / 12 / 18 / 24 / 48 & 96 hours ?
> www.en.wikipedia.org/wiki/Proportionality_(mathematics)
> www.en.wikipedia.org/wiki/Water
> www.en.wikipedia.org/wiki/Fasting
> 0104 www.tinyurl.com/2mdwdb [jan@metabol.su.se]
> 0104 www.tinyurl.com/37doxu [barbara.cannon@wgi.su.se]

EAT-less-OFTEN ... MAKE better AND better
BRAIN NERVE INSULIN [BNI]

What (?) is the probable significance [in relation to the consequences of 'EAT-less-OFTEN' meal frequency] of Fadool's 2000 BREAKTHROUGH discovery that BNI "levels are low after a meal" ... as regards the POSSIBLE better AND better EFFICIENCY of glucose fuel availability to brain/nerve tissue WHEN depression / dementia / Parkinson's / Alzheimer's [aka type 3 Diabetic] Patients / 'mood-swinging Diabetics' ... DECIDE to repeatedly Sing the song ...
"I-eat-less-OFTEN-I-fast-more-OFTEN"
> 0503 www.tinyurl.com/ys63gk [anson@jhu.edu]
> 1004 www.tinyurl.com/2b99ka [mattsonm@grc.nia.nih.gov]
> 0107 www.tinyurl.com/yta44e [giulio.passinetti@mssm.edu]
> 0107 www.tinyurl.com/2farm9 [temorgan@usc.edu]

And under what circumstances, of meal frequency [and/or NGry], would an adaptive increase in brain/nerve tissue 'Glucose Insulin Resistance' [neural GIR aka neural inflammation] be expected and for what reason ?
> 0382 www.tinyurl.com/2f5say [nancy.rothwell@manchester.ac.uk]
> 1206 www.tinyurl.com/y7znor [hmdosch@sickkids.ca]
> 0407 www.tinyurl.com/ynpp4g [raymond.swanson@ucsf.edu]
> 1007 www.tinyurl.com/3aypqg [mristow@mristow.org]

REMEMBER THE better AND better EVIDENCE
IS THAT ABOVE-AVERAGE 'BLOOD GLUCOSE'
IS HEALTHIER THAN any ARTIFICIAL LOWERING

PLEASE click on the following 2 web links ASAP and comment ASAP upon your current opinion / preference as to 1 or other of these 2 physiological 'conditions' ...
> www.en.wikipedia.org/wiki/Hypoglycemia
> www.en.wikipedia.org/wiki/Hyperglycemia

Plasma blood glucose [PGc] concentrations depend upon the level of water HYDRATION concentration and are measured in either:

1. Milligrams per deciliter (mg/dL), in the United States and other countries (e.g. Japan, France, Egypt, Colombia); or

2. Millimoles per liter (mmol/L), which can be acquired by dividing (mg/dL) by factor of 18.

Scientific journals are moving towards using mmol/L; some journals now use mmol/L as the primary unit but quote also mg/dl.

Comparatively:

* 72 mg/dL = 4 mmol/L
* 90 mg/dL = 5 mmol/L
* 108 mg/dL = 6 mmol/L
* 126 mg/dL = 7 mmol/L
* 144 mg/dL = 8 mmol/L
* 180 mg/dL = 10 mmol/L
* 270 mg/dL = 15 mmol/L
* 288 mg/dL = 16 mmol/L
* 360 mg/dL = 20 mmol/L
* 396 mg/dL = 22 mmol/L
* 594 mg/dL = 33 mmol/L

UNdrugTREATED type 2 Diabetics and other healthy People should test daily with ChemStrips and pause from eating, and drink just clean [EG filtered] water, until their urine is glucose free. The less carbohydrate eaten ... the less time between meals.
> 0506 www.tinyurl.com/2542a6 [stephane.dalle@igf.cnrs.fr]

That is how to CURE type 2 diabetes and prevent all 'newly diagnosed' type 1 & type 2 diabetes.

In respect of ALL the opinions included within this comment ... please AnyOne ... ALSO ask your current Specialist for advice including the provision of supporting Peer reviewed references evidencing their understanding of this important matter.
> 1207 www.tinyurl.com/2vp4e9 [DrBernarr@aol.com]

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ SAT.22.DEC.2007 @ 22:33hrs (C) "I-eat-less-OFTEN-I-fast-more-OFTEN".

Eating less OFTEN is profoundly more healthy than eating less...
> www.tinyurl.com/23akqw [Relative-HYPOglycemia]
> 0400 tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
> 0501 tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
> 0503 tinyurl.com/ys63gk [anson@jhu.edu]
> 0407 tinyurl.com/29kvda [zangend@hadassah.org.il]
> 1007 tinyurl.com/3aypqg [mristow@mristow.org]
> www.DiabetesHealth.com/read/2007/12/19/5575.html
> www.DiabetesHealth.com/read/2007/12/03/5558.html
> www.DiabetesHealth.com/read/2007/11/29/5564.html
> www.DiabetesHealth.com/read/2007/11/27/5541.html
> www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]
> www.HealSelf.org/Alzheimer's%20Disease.html
> www.en.wikipedia.org/wiki/Water
> www.en.wikipedia.org/wiki/Surge_protection
> www.en.wikipedia.org/wiki/Sunny_von_B%C3%BClow
> www.en.wikipedia.org/wiki/Proportionality_(mathematics)
> www.en.wikipedia.org/wiki/Pancreas
> www.en.wikipedia.org/wiki/Non-epileptic_seizure
> www.en.wikipedia.org/wiki/Neuroglycopenia
> www.en.wikipedia.org/wiki/Leukocytosis
> www.en.wikipedia.org/wiki/Ketosis
> www.en.wikipedia.org/wiki/Irrigation
> www.en.wikipedia.org/wiki/Insulin-like_growth_factor
> www.en.wikipedia.org/wiki/Insulin
> www.en.wikipedia.org/wiki/Hypoglycemia
> www.en.wikipedia.org/wiki/Hyperglycemia
> www.en.wikipedia.org/wiki/HbA1c
> www.en.wikipedia.org/wiki/Gluconeogenesis
> www.en.wikipedia.org/wiki/Glucagon
> www.en.wikipedia.org/wiki/Fasting
> www.en.wikipedia.org/wiki/Cerebrospinal_fluid
> www.en.wikipedia.org/wiki/C-peptide
> www.en.wikipedia.org/wiki/%C3%89mile_Cou%C3%A9
> www.en.wikipedia.org/wiki/Anti-diabetic_drug
> 1207 www.tinyurl.com/24nktv [LoveDiabetes.com]
> 1207 www.tinyurl.com/3buzxn [Suzanne_DeLaMonte_MD@Brown.edu]
> 1207 www.tinyurl.com/2k6979 [BetterCell.blogspot.com]
> 1207 www.tinyurl.com/2vp4e9 [DrBernarr@aol.com]
> 1207 www.tinyurl.com/29udcr [carol.johnston@asu.edu]
> 1207 www.tinyurl.com/3x9qh6 [ScienceDaily.com]
> 1107 www.tinyurl.com/2u88dx [mattsonm@grc.nia.nih.gov]
> 1107 www.tinyurl.com/2nvcqv [brancori@terra.com.br]
> 1007 www.tinyurl.com/3aypqg [mristow@mristow.org]
> 1007 www.tinyurl.com/3bcr7h [LoveDiabetes.com]
> 0807 www.tinyurl.com/24e67s [Matthew.Sadgrove@duke.edu]
> 0607 www.tinyurl.com/2v2pyx [malcolm@llp.org.uk]
> 0407 www.tinyurl.com/yog6oe [sm87j@nih.gov]
> 0407 www.tinyurl.com/2mffcj [zinman@mshri.on.ca]
> 0407 www.tinyurl.com/ynpp4g [raymond.swanson@ucsf.edu]
> www.TheDiabetesBlog.com/2007/04/19/no-food-no-problem
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
> 0307 www.tinyurl.com/2v3lxs [LoveDiabetes.com]
> 0307 www.tinyurl.com/yqmqnj [Kauffman@hslc.org]
> 0307 www.tinyurl.com/28lr3g [barbara.cannon@wgi.su.se]
> 0107 www.tinyurl.com/yta44e [giulio.passinetti@mssm.edu]
> 0107 www.tinyurl.com/yuh3q8 [mattisonj@mail.nih.gov]
> 0107 www.tinyurl.com/378bwo [martin.rutter@coch.nhs.uk]
> 0107 www.tinyurl.com/2farm9 [temorgan@usc.edu]
> 0107 www.tinyurl.com/2eyxy3 [john.wahren@ki.se]
> 1206 www.tinyurl.com/y7znor [hmdosch@sickkids.ca]
> 1106 www.tinyurl.com/2bn2g7 [carol.johnston@asu.edu]
> 1006 www.tinyurl.com/2hnp9h [lmr@dadlnet.dk]
> 0906 www.tinyurl.com/yuqqes [Mark Mayer]
> 0906 www.tinyurl.com/2jh8cj [MayoClinic.com]
> 0506 www.tinyurl.com/2542a6 [stephane.dalle@igf.cnrs.fr]
> 1204 www.tinyurl.com/2gcjdn [francesca_messina@yahoo.it]
> 1004 www.tinyurl.com/2b99ka [mattsonm@grc.nia.nih.gov]
> 0904 www.tinyurl.com/7ggyq [carol.johnston@asu.edu]
> 0704 www.tinyurl.com/2xx6ps [JML@biostat.bsc.gwu.edu]
> 0104 www.tinyurl.com/2mdwdb [jan@metabol.su.se]
> 0104 www.tinyurl.com/37doxu [barbara.cannon@wgi.su.se]
> 1203 www.tinyurl.com/39zu9o [Lori A Markham]
> 0903 www.tinyurl.com/2owwsn [skarch@sonic.net]
> 0803 www.tinyurl.com/2tp6vo [efeldman@umich.edu]
> 0503 www.tinyurl.com/ys63gk [anson@jhu.edu]
> 0103 www.tinyurl.com/2arzxs [DiabetesCaseStudy.com]
> 0103 www.tinyurl.com/2rh6fz [hmdosch@sickkids.ca]
> 0402 www.tinyurl.com/2e8uw7 [joy.dauncey@bbsrc.ac.uk]
> 0202 www.tinyurl.com/2rhf7p [Robert R. Barefoot]
> 0501 www.tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
> 0400 www.tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
> 1098 www.tinyurl.com/38cr65 [Turner UKPDS 33]
> 1197 www.tinyurl.com/34lyyj [lobnig@med.uni-duesseldorf.de]
> 0297 www.tinyurl.com/yu77y7 [m.henricsson@telia.com]
> 0195 www.tinyurl.com/2lb5om [jolefsky@ucsd.edu]
> 0993 www.tinyurl.com/2xbcs8 [DCCT 1993]
> 0491 www.tinyurl.com/2eqls2 [DCCT 1991]
> 1188 www.tinyurl.com/2mcvz8 [DCCT 1988]
> 1287 www.tinyurl.com/2d48d5 [juangrun@mail.med.upenn.edu]
> 0382 www.tinyurl.com/2f5say [nancy.rothwell@manchester.ac.uk]
> 0178 www.tinyurl.com/33q5rt [ndic@info.niddk.nih.gov]
> 0166 'Relative-HYPOglycemia As A Cause Of Neuropsychiatric Illness' @ Journal Of The National Medical Association @ Harry M Salzer MD @ January 1966 @ Vol 58 @ Number 1 @ Table 1 @ Figure 2.
> 0124 "Hyperinsulinism and Dysinsulinism" @ J.A.M.A @ Seale Harris @ 1924 @ Vol 83 @ page 729-733.

Posted by Nicholas Dynes Gracey on 24 December 2007

Now there is a choice ... a Person can choose to be medicated or alternatively a Person can choose to "eat less OFTEN" ... because it is 'eating too OFTEN' that CAUSES diabetes ... an above average plasma glucose concentration [PGc] ... in a Diabetic's body.

Posted by bird54 on 16 December 2007
http://www.diabeteshealth.com/read/2007/11/29/5564.html

"... What if diabetes is not a disease at all, but a normal response to an overabundance of food? What if the cure is so simple, that we, in all of our knowledge have overlooked it? What if the answer really is "easy"? What if the cure to diabetes is to eat less often? What if diabetics could cure their diabetes by intermittent fasting? What if people could reverse their diabetes by drinking only fresh water as meal replacements, and eating only when they were hungry, instead of overeating because they are told by their health care practitioners, "Never skip a meal. Always eat breakfast. Eat many small balanced meals throughout the day." So they do that, and they watch themselves get fatter and fatter. Then they wonder, "How did I get diabetes? I followed all the rules!" ..."

Hi bird54 & AnyOne else...
If diabetes is not a disease at all, but a normal response to an overabundance of food(?) ...

... Then WHY is diabetes not a disease at all, but a normal response to "eating too often" ?

The CAUSE of diabetes was apparently first published as early as 1938 by Dr Michael Somogyi.
> www.en.wikipedia.org/wiki/Chronic_Somogyi_rebound

MICHAEL SOMOGYI
> www.en.wikipedia.org/wiki/Michael_Somogyi
1. Somogyi, M, Kirstein, M: Insulin as a cause of extreme hyperglycemia and instability. Week Bull St Louis M Soc 32: 498, 1938.
2. Somogyi, M: Exacerbation of diabetes by excess insulin action. Am J Med, 26: 169-191, 1959.
3. Rosenbloom, AL, Giordano, BP: Chronic over-treatment with insulin in children and adolescents. Am J Dis Child 131: 881-885, 1977.
4. Gale, EA, Kurtz, AB, Tattersall, RB: In search of the Somogyi effect. Lancet 2: 279-282, 1980.
5. Bolli, GB, Gottesman, IS, Campbell, PJ, Haymond, MW, Cryer, PE, Gerich, JE: Glucose counter-regulation and waning of insulin in the Somogyi phenomenon (post-hypoglycemic hyperglycemia). N Engl J Med 311: 1214-9, 1984.
6. Cryer, PE, Gerich, JE: Glucose counter-regulation, hypoglycemia, and intensive insulin therapy in diabetes mellitus. NEngl J Med 313: 232-241, 1985.
7. Walker, H: Michael Somogyi, PhD (1883-1971) Metabolism 21: 589-590, 1972.
8. Gee, DA: Working Wonders. A History of the Jewish Hospital of St. Louis 1891-1992.
9. Szállási, Á: Egy ismert effektus alig ismert névadója. Somogyi Mihály (1883-1971). Orvosi Hetilap 142: 1749-1750, 2001.
10. Jobst, K: A kémikus diabetologus. Lab Diagn 21: 295, 1994.
11. Kollind, M, Lins, PE, Adamson, U: The man behind the phenomenon. Michael Somogyi and blood glucose regulation in unstable diabetes. A controversial hypothesis still discussed. Lakartidningen 88: 878-879, 1991.
12. Kirstein, MB, Pareira, MD, Sachar, LA, Wasserman, HC: Twenty years of diastase and pancreatitis investigation at the Jewish Hospital of Saint Louis, Missouri, Bull of the St. Louis Jewish Hospital staff 8: 12-19, 1951.
> 0198 www.tinyurl.com/yr27rt [okh@hst.aau.dk]
> www.en.wikipedia.org/wiki/Intensive_insulinotherapy
> www.en.wikipedia.org/wiki/Conventional_insulinotherapy

Somogyi's discovery suggests that "eating too often" can cause 'surges' of pancreatic beta-cell insulin [BCI] to be produced ...
> www.en.wikipedia.org/wiki/Hyperinsulinemia

... AND that surges of BCI can cause plasma glucose concentration [PGc] to be reduced too low and/or well below 72 mg/dL IE 4 mmol/L PGc
> www.en.wikipedia.org/wiki/Image:Somogyi_rebound.GIF

... BECAUSE the BCI surges 'pump' glucose out of the blood plasma and >>> into fat cells, into muscle cells & into liver cells www.en.wikipedia.org/wiki/Diabetic_hypoglycemia

... SO to protect the brain/nerves from glucose starvation the brain instructs Transient Supernormal-Glycemia [TSG aka HYPERglycemia aka diabetes] IE glucose production from the LIVER and diabetes is produced ... where the Diabetic HYPERglycemia is saving the life of the Diabetic fortunate enough to have adaptively manifested the diabetes-response to 'the Somogyi effect'.
> www.en.wikipedia.org/wiki/Hypoglycemia
> www.en.wikipedia.org/wiki/Glucagon
> www.en.wikipedia.org/wiki/Gluconeogenesis
> 0103 www.tinyurl.com/yszb9q [rortiz1@tulane.edu]

DIABETES PREVENTS SCHIZOPHRENIA
> 0367 www.tinyurl.com/2uxb99 [Dr Allan Cott]
> 0293 www.tinyurl.com/3xh4ne [OrthoMolecularHealth.org]
> www.en.wikipedia.org/wiki/Schizophrenia
> 0407 www.tinyurl.com/2e3n8b [nutritional distressor]
> www.tinyurl.com/2459gp [Neuro-Glyco-Penia]

... BUT if the Diabetic is fortunate enough to "eat less OFTEN" ... this practice gradually adapts the fat/muscle/liver cells to the glucose / insulin surges by way of increasing peripheral tissue glucose insulin resistance [GIR] ... to 'amplify' the efficiency of glucose delivery to the brain/nerves the Person's also adaptively manifests decreased brain/nerve tissue glucose insulin resistance GIR to brain nerve insulin [BNI] so that the PGc available for supply to the brain/nerves can more efficiently be delivered, by the blood-stream, to the brain/nerves.
> 1107 www.tinyurl.com/2u88dx [mattsonm@grc.nia.nih.gov]
> 1007 www.tinyurl.com/3aypqg [mristow@mristow.org]
> 0503 www.tinyurl.com/ys63gk [anson@jhu.edu]
> 0501 www.tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
> 0400 www.tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]

bird54 PLEASE discuss your opinion as to these relatively new proposals ... that 'insulin resistance' is ALWAYS BENEFICIAL and that a lack of 'insulin resistance' and/or diabetes may well explain the disease of Schizophrenia; and in respect of Somogyi's 1938 discovery & associated references ... what steps would You advise/speculate to maximize the Honeymoon Period for any newly diagnosed type 1 Diabetic?
> www.TheDiabetesBlog.com/2007/04/03/the-honeymoon-period
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
> 0802 www.tinyurl.com/2qxuzh [Fortunato.Lombardo@unime.it]
> 1207 www.tinyurl.com/3au3a5 [LoveDiabetes.com]

In respect of ALL the opinions included within this comment ... please AnyOne ... ALSO ask your current Specialist for advice including the provision of supporting Peer reviewed references evidencing their understanding of this important matter.
> 1207 www.tinyurl.com/2vp4e9 [DrBernarr@aol.com]

…Warm thanks & AdrenalinLove; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ MON.24.DEC.2007 @ 21:23hrs (C) "I-eat-less-OFTEN-I-fast-more-OFTEN".

Eating less OFTEN is profoundly more healthy than eating less...
> 0400 tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
> 0501 tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
> 0503 tinyurl.com/ys63gk [anson@jhu.edu]
> 0407 tinyurl.com/29kvda [zangend@hadassah.org.il]
> 1007 tinyurl.com/3aypqg [mristow@mristow.org]
> www.DiabetesHealth.com/read/2007/12/19/5575.html
> www.DiabetesHealth.com/read/2007/12/03/5558.html
> www.DiabetesHealth.com/read/2007/11/27/5541.html
> 1107 www.tinyurl.com/2hdnt9 [gyula.soltesz@aok.pte.hu]
> 0176 www.tinyurl.com/2vzlps [jackie.wallace@faht.scot.nhs.uk]
> www.en.wikipedia.org/wiki/Parkinson%27s_disease
> www.HealSelf.org/Alzheimer's%20Disease.html
> www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]

Posted by Nicholas Dynes Gracey on 25 December 2007

It is 'Eating too OFTEN' that is the main avoidable CAUSE that CAUSES and sustains "diabetes" ... an above average plasma glucose concentration ... inside of a Diabetic's blood-stream.

Inside the blood-stream is outside the tissues [aka organs].

Every day excess 'water-soluble' substances, inside the blood-stream, can easily be [and naturally are] urinated to outside of the body EG excess urea, excess salt, excess glucose, excess vitamins, excess water.

Now there is a choice ... a Diabetic can choose to be medicated to rapidly force excess glucose from outside of their tissues into >>> the inside of their tissues OR alternatively a Diabetic can CHOOSE to "eat less OFTEN" [every day better in every way] to encourage glucose, from inside their blood-stream, to be gradually better digested [and/or expelled, by urination, to outside of their blood-stream, into their bladder and outside of their body].

The CAUSE & CURE for type 1, type 2, type 3 & type 4 diabetes is set out and reference-linked above & below...
> 1207 www.tinyurl.com/2v9ajm [LoveDiabetes.com]

What is your CHOICE & why?

Happy Christmas and All health to YourSelf, Family & AnyOne else.

In respect of ALL the opinions included within & associated with this comment ... please AnyOne ... ALSO ask your current Specialist for advice, including the provision of supporting Peer reviewed references, evidencing their understanding of this important matter.
> 1207 www.tinyurl.com/2vp4e9 [DrBernarr@aol.com]

…Warm thanks & AdrenalinLove :)
Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ TUE.25.DEC.2007 @ 23:17hrs (C) "I-eat-less-OFTEN-I-fast-more-OFTEN".

Eating less OFTEN is profoundly more healthy than eating less...
> 0400 www.tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
> 0501 www.tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
> 0503 www.tinyurl.com/ys63gk [anson@jhu.edu]
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
> 1007 www.tinyurl.com/3aypqg [mristow@mristow.org]
www.DiabetesHealth.com/read/2007/12/19/5575.html
www.DiabetesHealth.com/read/2007/12/03/5558.html
www.DiabetesHealth.com/read/2007/11/29/5564.html
www.DiabetesHealth.com/read/2007/11/27/5541.html
> 0108 www.tinyurl.com/39dbyo [rosenal@peds.ufl.edu]
> 0806 www.tinyurl.com/23x2nv [vbhatia@sgpgi.ac.in]
> 0101 www.tinyurl.com/2r293z [nsglaser@ucdavis.edu]
> 0100 www.tinyurl.com/ypozqv [rosenal@peds.ufl.edu]
> 1107 www.tinyurl.com/yrr5kd [LoveDiabetes.com]
> www.en.wikipedia.org/wiki/Parkinson%27s_disease
> www.HealSelf.org/Alzheimer's%20Disease.html
> www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]

Posted by bird54 on 25 December 2007

Merry Christmas Nick and Anyone Else!
I've been reading back on all the comments, and wow! There is a lot of information to absorb.
The research supporting "eating less often, fasting more often" is astounding. I think that if one looks at a meal as a "reward" for a hard day's work, then it is easy to fast all day. Now that I eat less often, I get excited about eating dinner, and I look forward to it all day, whereas before, it was a chore--I had to eat breakfast whether or not I was hungry because I didn't want to "ruin my metabolism" by not eating the "most important" meal of the day. I often ate snacks and meals, not because I was hungry, but because I wanted to make sure I got all my nutrients to prevent disease. Now when I look at all the research, it makes sense not to eat so often.

The tinyurl.com/3aypqg link states that "…nutritive calorie restriction increases life expectancy. Accordingly, treatment …with different antioxidants and vitamins prevents extension of life span...questioning current treatments of type 2 diabetes as well as the widespread use of antioxidant supplements."

Recently I watched an advertisement on TV: A neurosurgeon was promoting his product of antioxidants for brain health. He stated that to get as many antioxidants as were in his product, one would have to consume an enormous amount of food. He showed plates and plates piled full of meats and vegetables-- more than anyone could possibly eat in a day without becoming sick or morbidly obese. And I remember thinking: This does not make any sense to me at all. If humans were meant to eat that much food or take that many pills to get the necessary nutrients, then the human race would have died out long ago.
I think that our hunter-gatherer ancestors survived on a lot less food than we eat today. I'm sure they didn't have 4-6 meals a day. And they certainly didn't have grocery stores or fast food restaurants to run to whenever their cupboards were bare.
Modern man abuses his body and then looks for quick fixes in the form or pills and drugs, instead of relying on the wisdom of the ages.

Posted by bird54 on 25 December 2007

Hi Nick and Anyone Else,
A while ago I read an interesting book which explained the genetic reasons for many diseases including type 1 diabetes. The book is titled:
Survival of the Sickest: A Medical Maverick Discovers Why We Need Disease (Hardcover)
by Sharon Moalem (Author), Jonathan Prince (Author)
If memory serves me correctly, the book states that diabetes actually served a purpose in the last ice age--it allowed the body to burn sugar for energy--and that is why type 1 diabetes is more common in Northern Europeans. Using the theories of this book in addtion to all the research you listed, it seems reasonable to conclude that all types of diabetes serve some purpose. We should not view diseases as negative, but attempt to find the reason for them. The book talked about "jumping genes" and how your grandmother's lifestyle had more influence on your genes than your mother. Nowadays scientists are looking for the genetic causes of diseases, as if these "mutations" are harmful, rather than focusing on how these genes benefited us and allowed us to survive the conditions during a particular time in history.

Posted by Nicholas Dynes Gracey on 26 December 2007

It is 'Eating less OFTEN' that is the main available CURE that CURES relative-HYPOglycemia and thereby avoids and/or CURES "diabetes" ... an above average plasma glucose concentration ... inside of a Diabetic's blood-stream which protects every Diabetic from the extra-ordinary challenges of relative-HYPOglycemia.

Inside the blood-stream is outside the tissues [aka organs].

Every day excess 'water-soluble' substances, inside the blood-stream, can easily be [and naturally are] urinated to outside of the body EG excess urea, excess salt, excess glucose, excess vitamins, excess water.

Now there is a choice ... a Diabetic can choose to be medicated to rapidly force excess glucose from outside of their tissues into >>> the inside of their tissues OR alternatively a Diabetic can CHOOSE to "eat less OFTEN" [every day better in every way] to encourage glucose, from inside their blood-stream, to be gradually better digested [and/or expelled, by urination, to outside of their blood-stream, into their bladder and outside of their body].
> 1007 www.tinyurl.com/3aypqg [mristow@mristow.org]

The CAUSE & CURE for all 5 types of 'Relative-HYPO-glycemia disease' aka ... type 0, type 1, type 2, type 3 & type 4 diabetes ... is set out and reference-linked above & below...
> 1207 www.tinyurl.com/3au3a5 [LoveDiabetes.com]
http://www.TheDiabetesBlog.com/2007/04/03/the-honeymoon-period
> 1207 www.tinyurl.com/2v9ajm [LoveDiabetes.com]
> 0802 www.tinyurl.com/2qxuzh [Fortunato.Lombardo@unime.it]
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
> 1107 www.tinyurl.com/yrr5kd [LoveDiabetes.com]
> 0367 www.tinyurl.com/2uxb99 [Dr Allan Cott]

What is your CHOICE & why?

Posted by bird54 on 25 December 2007
www.DiabetesHealth.com/read/2007/11/29/5564.html

"... The research supporting "eating less often, fasting more often" is astounding. I think that if one looks at a meal as a "reward" for a hard day's work, then it is easy to fast all day. Now that I eat less often, I get excited about eating dinner, and I look forward to it all day, whereas before, it was a chore--I had to eat breakfast whether or not I was hungry because I didn't want to "ruin my metabolism" by not eating the "most important" meal of the day. I often ate snacks and meals, not because I was hungry, but because I wanted to make sure I got all my nutrients to prevent disease. Now when I look at all the research, it makes sense not to eat so often. ..."

Posted by Sarah on 26 December 2007
> 1207 www.tinyurl.com/2xq29m [LoveDiabetes.com]

"... Note: Type 1 diabetes is an autoimmune disease ..."

Posted by Sarah on 26 December 2007
> 1207 www.tinyurl.com/yod977 [LoveDiabetes.com]

"... Also note that true Type 1 diabetics do NOT HAVE INSULIN RESISTANCE ... I am VERY insulin sensitive ..."

Hi bird54, Sarah, Julie & AnyOne else...
Please note that eating less OFTEN reduces inflammation [aka auto-immune disease] & increases glucose insulin resistance [GIR] ... and those are 2 of the means by which eating less OFTEN can CURE type 0, type 1, type 2, type 3 & type 4 diabetes.
> 0187 www.tinyurl.com/329umr [hans.lithell@pubcare.uu.se]
> 1007 www.tinyurl.com/3aypqg [mristow@mristow.org]
> 1207 www.tinyurl.com/27pwj8 [saskiananette@hotmail.com]

Why choose to eat more OFTEN when eating less OFTEN can reduce auto-immune disease, increase glucose insulin resistance [GIR] and CURE diabetes?

Levels of insulin need to be very carefully regulated and Athletes commonly have relatively extraordinary low basal levels of pancreatic beta-cell insulin [BCI]. Relatively less OFTEN 'surges' of pancreatic beta-cell insulin [BCI] are usually better ... unless more insulin is accompanied by an appropriate level of REGULATORY glucose insulin resistance [GIR] ... then arguably the more brain/nerve insulin [BNI] the better ...
> 1007 tinyurl.com/3aypqg [mristow@mristow.org]

FORTUNATELY type 0, 1, 2, 3 or 4 diabetes all involve protective glucose insulin resistance [GIR] and can be assisted by reduced inflammation [aka auto-immunity] ... for example please comment on this reference ...
> 1206 www.tinyurl.com/y7znor [hmdosch@sickkids.ca]

In my opinion type 1 Diabetics can benefit a great deal from glucose insulin resistance [which appears to be one of the PROTECTIVE roles of C-peptide]. One of the functions of glucose insulin resistance GIR is to re-route glucose to the brain/nerves and thereby PROTECT the body from relative-HYPOglycemia. Apparently, from reading BetterCell's blog, it appears BetterCell's glucose insulin resistance GIR is relatively LOW ... especially on the day of his recent alarming challenges with apparent severe relative-HYPOglycemia / mild absolute-HYPOglycemia ...
> 1207 www.tinyurl.com/2k6979 [BetterCell.blogspot.com]

It is certainly apparent that most type 1 Diabetics would benefit from MORE glucose insulin resistance [GIR] / C-peptide.
> 0107 www.tinyurl.com/2eyxy3 [john.wahren@ki.se]

What's new about this understanding is understanding the profound similarities, in common, between type 0 & 1 & 2 & 3 diabetes ... all of which are apparently triggered & sustained [ie 'the CAUSE'] by 'cyclical neural starvation' of glucose availability, to the brain/nerves, aka "relative-HYPOglycemia".

Diabetes is NOT a disease [it is the associated 'HYPOglycemia' that is the 'disease'] ... diabetes aka HYPERglycemia [that can exist for years] is a 'physiological body state' that protects the nervous system [especially the brain] from the extraordinary dangers of ... beta-cell and/or HYPERinsulinemia [excess insulin] associated ... "relative-HYPOglycemia" [which starves the nervous system of fuel and can result in profound challenges within minutes or even seconds with little or zero notice].

Beta-cell and/or HYPERinsulinemia [excess insulin] associated "relative-HYPOglycemia" is the apparent reason, in my opinion, for adaptative 'auto-immune' down-regulation of beta-cells c/o the body's immune system [and could reasonably be described as 'Alzheimers of the beta-cell-brain']
> 0103 www.tinyurl.com/2rh6fz [hmdosch@sickkids.ca]

In my opinion UNdrugTREATED type 2 diabetes [aka "cellular dietary restriction"] is a protective adaptative response which, by means of protecting the brain from "relative-HYPOglycemia", can be expected to reduce or eliminate type 3 diabetes aka 'Alzheimers'.
> 0107 www.tinyurl.com/2farm9 [temorgan@usc.edu]

In respect of ALL the opinions included within & associated with this comment ... please AnyOne ... ALSO ask your current Specialist for advice, including the provision of supporting Peer reviewed references, evidencing their understanding of this important matter.
> 1207 www.tinyurl.com/2vp4e9 [DrBernarr@aol.com]

…Warm thanks & AdrenalinLove :)
Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ WED.26.DEC.2007 @ 23:27hrs (C) "I-eat-less-OFTEN-I-fast-more-OFTEN".

Eating less OFTEN is profoundly more healthy than eating less...
> 0400 www.tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
> 0501 www.tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
> 0503 www.tinyurl.com/ys63gk [anson@jhu.edu]
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
> 1007 tinyurl.com/3aypqg [mristow@mristow.org]
www.DiabetesHealth.com/read/2007/12/19/5575.html
www.DiabetesHealth.com/read/2007/12/03/5558.html
www.DiabetesHealth.com/read/2007/11/29/5564.html
www.DiabetesHealth.com/read/2007/11/27/5541.html
> 0108 www.tinyurl.com/39dbyo [rosenal@peds.ufl.edu]
> 1207 www.tinyurl.com/2k6979 [BetterCell.blogspot.com]
> 1207 www.tinyurl.com/27pwj8 [saskiananette@hotmail.com]
> 1107 www.tinyurl.com/yrr5kd [LoveDiabetes.com]
> 0107 www.tinyurl.com/2eyxy3 [john.wahren@ki.se]
> 0107 www.tinyurl.com/2farm9 [temorgan@usc.edu]
> 1206 www.tinyurl.com/y7znor [hmdosch@sickkids.ca]
> 0806 www.tinyurl.com/23x2nv [vbhatia@sgpgi.ac.in]
> 0103 www.tinyurl.com/2rh6fz [hmdosch@sickkids.ca]
> 0101 www.tinyurl.com/2r293z [nsglaser@ucdavis.edu]
> 0100 www.tinyurl.com/ypozqv [rosenal@peds.ufl.edu]
> 0187 www.tinyurl.com/329umr [hans.lithell@pubcare.uu.se]
> www.en.wikipedia.org/wiki/Parkinson%27s_disease
> www.HealSelf.org/Alzheimer's%20Disease.html
> www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]
Eating less OFTEN can CURE any diabetes
.

Posted by bird54 on 26 December 2007

Thank you, Nick, for all the info. I went to www.tinyurl.com/2farm9 and then clicked on all the "related links". There is more information on the benefits of restriced diets, intermittent fasting, and exercise that show how it reduces inflammation, increases brain health and extends lifespan. I wonder why health care professionals never tell us the benefits of fasting but instead push drugs and medications. You hear them say, "diet and exercise" but they never recommend fasting. I think they have left out the most important factor.

Posted by bird54 on 27 December 2007

Hi Nick and Anyone Else,
I found another article that states that fasting is good for the heart.

http://articles.mercola.com/sites/articles/archive/2007/12/27/does-monthly-fasting-help-your-heart.aspx

http://www.dallasnews.com/sharedcontent/dws/fea/healthyliving2/stories/DN-nh_fastfiller_1127liv.ART.State.Edition1.36db77a.html

"Diabetics who were studied and who fasted... were found to have healthier arteries. Diabetics, however, are never encouraged to skip meals, Dr. Horne emphasized."

WHY NOT?!

I think that it is very puzzling that even though there is overwhelming evidence to the benefits of fasting, diabetics are discouraged from fasting.

Posted by bird54 on 27 December 2007

The most ridiculous thought of the day:
One should not skip meals or go on a ketogenic diet without their doctor's supervision, yet one can eat unlimited amounts of junk food and candy without any supervision at all!

Posted by Nicholas Dynes Gracey on 27 December 2007

What is your CHOICE & why?
> 0367 www.tinyurl.com/2uxb99 [Dr Allan Cott]

Posted by bird54 on 26 December 2007
www.DiabetesHealth.com/read/2007/11/29/5564.html

'... Thank you, Nick, for all the info. I went to www.tinyurl.com/2farm9 and then clicked on all the "related links". There is more information on the benefits of restricted diets, intermittent fasting, and exercise that show how it reduces inflammation, increases brain health and extends lifespan. I wonder why health care professionals never tell us the benefits of fasting but instead push drugs and medications. You hear them say, "diet and exercise" but they never recommend fasting. I think they have left out the most important factor. ...'

Posted by bird54 on 27 December 2007
www.DiabetesHealth.com/read/2007/11/29/5564.html

'... Hi Nick and Anyone Else,
I found another article that states that fasting is good for the heart.
> 1107 www.tinyurl.com/2gxkqt [Mercola.com]
> 1107 www.tinyurl.com/ytm65u [carolyn_susma@bpost.com]

"Diabetics who were studied and who fasted... were found to have healthier arteries. Diabetics, however, are never encouraged to skip meals, Dr. Horne emphasized."

WHY NOT?!

I think that it is very puzzling that even though there is overwhelming evidence to the benefits of fasting, diabetics are discouraged from fasting.

The most ridiculous thought of the day:
One should not skip meals or go on a ketogenic diet without their doctor's supervision, yet one can eat unlimited amounts of junk food and candy without any supervision at all! ...'

Hi bird54, Sarah, Julie & AnyOne else...
Please note that "fasting" is really another name for "digestion" and providing reasonable time for proper digestion reduces inflammation [aka auto-immune disease] & increases peripheral glucose insulin resistance [GIR] ... and those are just two of the means by which eating less OFTEN can CURE type 0, type 1, type 2, type 3 & type 4 diabetes.
> 0187 www.tinyurl.com/329umr [hans.lithell@pubcare.uu.se]
> 1007 www.tinyurl.com/3aypqg [mristow@mristow.org]
> 1207 www.tinyurl.com/27pwj8 [saskiananette@hotmail.com]

Certain People, at certain times of their lives, have a reduction in their powers of "digestion". A lack of ability to digest nuts is called an acute allergy. Such acute allergies are caused by 'indigestion' leading to gall-congested ducts within the liver caused by eating too OFTEN.

The lack of optimum nut-digestive capacity of certain areas of the liver then leads to an allergic response aka inflammation associated with a delayed process of "digestion" and partially digested chemicals arise, together with subsequent inflammatory digestive processes, including leukocytosis, away from the liver.
> 0202 www.tinyurl.com/2rzxgu [topole@ccf.org]
> www.en.wikipedia.org/wiki/Leukocytosis

A lack of ability to digest glucose could be called a chronic allergy. Such a chronic allergy is associated with 'indigestion' leading to gall-congested ducts within the liver caused by eating too OFTEN.

The lack of optimum glucose-digestive capacity of certain areas of the liver then leads to a chronic allergic response in the form of precision controlled 'futile-cycles' of regulatory HYPERglycemia-correcting-HYPOglycemia to which the body quickly adapts [c/o insulin C-peptide etc] by increasing glucose insulin resistance [GIR] in tissues peripheral to the brain/nerves in order to prevent the relative-HYPOglycemia, of the brain/nerves, that is caused by HYPERinsulinism from the beta-cells [caused by eating too OFTEN]. A chronic allergic response aka inflammation aka auto-immunity toward the beta-cells arises to protect the body from chronic relative-HYPOglycemia and/or absolute-HYPOglycemia which arises due to insufficient peripheral tissue glucose insulin resistance [ptGIR].
> 1207 www.tinyurl.com/3au3a5 [LoveDiabetes.com]
> 1207 www.tinyurl.com/2v9ajm [LoveDiabetes.com]
> 1107 www.tinyurl.com/yrr5kd [LoveDiabetes.com]
http://www.TheDiabetesBlog.com/2007/04/03/the-honeymoon-period
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
> 0107 www.tinyurl.com/2eyxy3 [john.wahren@ki.se]
> 0802 www.tinyurl.com/2qxuzh [Fortunato.Lombardo@unime.it]
> 0367 www.tinyurl.com/2uxb99 [Dr Allan Cott]
> www.en.wikipedia.org/wiki/Michael_Somogyi
> Somogyi, M, Kirstein, M: Insulin as a cause of extreme hyperglycemia and instability. Week Bull St Louis M Soc 32: 498, 1938.
> Somogyi, M: Exacerbation of diabetes by excess insulin action. Am J Med, 26: 169-191, 1959.
> Rosenbloom, AL, Giordano, BP: Chronic over-treatment with insulin in children and adolescents. Am J Dis Child 131: 881-885, 1977.
> www.en.wikipedia.org/wiki/Image:Somogyi_rebound.GIF

Why choose to eat more OFTEN when eating less OFTEN and digesting more OFTEN can de-congest the liver, reduce auto-immune disease, reduce brain/nerve glucose insulin resistance [bnGIR], increase periperal tissue glucose insulin resistance [ptGIR] and CURE diabetes?
> 1107 www.tinyurl.com/37fh3g [ConditioningResearch.blogspot.com]

In respect of ALL the opinions included within & associated with this comment ... please AnyOne ... ALSO ask your current Specialist for advice, including the provision of supporting Peer reviewed references, evidencing their understanding of this important matter.
> 1207 www.tinyurl.com/2vp4e9 [DrBernarr@aol.com]

…Warm thanks & AdrenalinLove :)
Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ THU.27.DEC.2007 @ 23:07hrs (C) "I-eat-less-OFTEN-I-fast-more-OFTEN".

Eating less OFTEN is profoundly more healthy than eating less...

> 0400 www.tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
> 0501 www.tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
> 0503 www.tinyurl.com/ys63gk [anson@jhu.edu]
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
> 1007 tinyurl.com/3aypqg [mristow@mristow.org]
www.DiabetesHealth.com/read/2007/12/19/5575.html
www.DiabetesHealth.com/read/2007/12/03/5558.html
www.DiabetesHealth.com/read/2007/11/29/5564.html
www.DiabetesHealth.com/read/2007/11/27/5541.html
> 0108 www.tinyurl.com/39dbyo [rosenal@peds.ufl.edu]
> 1207 www.tinyurl.com/2k6979 [BetterCell.blogspot.com]
> 1207 www.tinyurl.com/27pwj8 [saskiananette@hotmail.com]
> 1207 www.tinyurl.com/3au3a5 [LoveDiabetes.com]
> 1207 www.tinyurl.com/2v9ajm [LoveDiabetes.com]
> 1107 www.tinyurl.com/yrr5kd [LoveDiabetes.com]
> 1107 www.tinyurl.com/2gxkqt [Mercola.com]
> 1107 www.tinyurl.com/ytm65u [carolyn_susma@bpost.com]
> 1107 www.tinyurl.com/37fh3g [ConditioningResearch.blogspot.com]
http://www.TheDiabetesBlog.com/2007/04/03/the-honeymoon-period
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
> 0107 www.tinyurl.com/2eyxy3 [john.wahren@ki.se]
> 0107 www.tinyurl.com/2farm9 [temorgan@usc.edu]
> 1206 www.tinyurl.com/y7znor [hmdosch@sickkids.ca]
> 0806 www.tinyurl.com/23x2nv [vbhatia@sgpgi.ac.in]
> 0103 www.tinyurl.com/2rh6fz [hmdosch@sickkids.ca]
> 0802 www.tinyurl.com/2qxuzh [Fortunato.Lombardo@unime.it]
> 0101 www.tinyurl.com/2r293z [nsglaser@ucdavis.edu]
> 0100 www.tinyurl.com/ypozqv [rosenal@peds.ufl.edu]
> 0187 www.tinyurl.com/329umr [hans.lithell@pubcare.uu.se]
> Rosenbloom, AL, Giordano, BP: Chronic over-treatment with insulin in children and adolescents. Am J Dis Child 131: 881-885, 1977.
> 0367 www.tinyurl.com/2uxb99 [Dr Allan Cott]
> Somogyi, M: Exacerbation of diabetes by excess insulin action. Am J Med, 26: 169-191, 1959.
> Somogyi, M, Kirstein, M: Insulin as a cause of extreme hyperglycemia and instability. Week Bull St Louis M Soc 32: 498, 1938.
> www.en.wikipedia.org/wiki/Michael_Somogyi
> www.en.wikipedia.org/wiki/Image:Somogyi_rebound.GIF
> www.en.wikipedia.org/wiki/Parkinson%27s_disease
> www.en.wikipedia.org/wiki/Leukocytosis
> www.HealSelf.org/Alzheimer's%20Disease.html
> www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]

Eating less OFTEN can CURE any diabetes

Posted by Nicholas Dynes Gracey on 28 December 2007

Posted by anonymous on 2 October 2007
www.DiabetesHealth.com/read/2007/04/11/5113.html

"...We live in one of the richest countries in the world. I wish there were people who would have rich enough souls so they would not sell out health of millions of people.
I also believe the cure is out there but the system makes more money exploiting this condition. May God bless those who are really working to cure this disease and those who will choose to bring it to fruition and be forever blessed by all who were ever touched with this condition. May honesty and love prevail..."
> 1007 www.tinyurl.com/35mnkk [Ian Clark]

Posted by Nicholas Dynes Gracey on 27 December 2007
www.DiabetesHealth.com/read/2007/11/29/5564.html

"...What is your CHOICE & why?
> 0367 www.tinyurl.com/2uxb99 [Dr Allan Cott]..."

Yesterday's post entitled as above ['diabetes or schizophrenia what is your CHOICE (?) & why(?)'] is dedicated to Dr Alan Cott, Dr Harry Salzer & Dr Debra Fadool because each of their references are brilliant in isolation ... and when cross-referenced their findings become extra-ordinary in helping with an explanation & understanding of diabetes. My guess is that Most would choose diabetes once it is understood how 'above-the-national-average' blood glucose concentration / transient supernormal glycemia [TSG] protects the brain/nerves from schizophrenia aka type 3b diabetes and Alzheimers aka type 3a diabetes [because greater concentrations of blood glucose facilitate improved brain functioning at certain times].
> 0400 www.tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
> 0367 www.tinyurl.com/2uxb99 [Dr Allan Cott]
> 'Relative-HYPOglycemia As A Cause Of Neuropsychiatric Illness' @ Journal Of The National Medical Association @ Harry M Salzer MD @ January 1966 @ Vol 58 @ Number 1 @ Table 1 @ Figure 2.

Posted by Sarah on 28 December 2007
> 1207 www.tinyurl.com/2nmll4 [LoveDiabetes.com]

"...I use 0.5 units per hour, and 1 unit can drop me from 19.7 mmol/l to 2.7 mmol/l. I often need less than 1 unit to bring down a high ... I got Type 1 as a baby ... and I fast ... Even if I go for 6 days without ANY food, I still need insulin ... I think we need to warn the ... public that Type 1 is NOT simply a matter of diet ... a gluten and casein free diet from birth MAY help prevent Type 1 in those at risk, as well as avoiding vaccines ... schizophrenia is LINKED to diabetes ... The medications used to treat schizophrenia are strongly linked to Type 2 diabetes ... What the heck are you saying? ... Do you REALLY know anything about TYPE 1 diabetes? ... Are you REALLY a researcher? ... I need insulin fasting, just like any other Type 1. This is called a "basal rate" ... I have autoimmunity to my beta cells. I eat gluten and casein free. I fast. I take Omega 3 and Vitamin D supplements. I eat healthy. I work out. And yet I am still a "severe" diabetic ... you would need to help them regenerate their lost beta cells ... Note that Type 1 diabetes is simply another autoimmune disease like Lupus or MS, just affecting the pancreas. If we can cure one, we can cure them all ... an nut allergy ... An allergy is an IgE *immune response* ... I also forgot to add that even with insulin (normal basal rate), my blood sugars can be dangerously high for no known reason, even if I DO NOT EAT. More than food raises blood glucose in a T1 ... And don't suggest "exercise" for a dangerously high blood sugar in a Type 1. Exercising will INCREASE the blood sugar ... the body will burn fat for energy and create ketones ... If you can suggest a "diet" that will *actually* cure AUTOIMMUNE diabetes (i.e. the kind triggered in thin people by a virus/pathogen/toxin/protein) and has no side effects like coma and death, please do ... What the heck is "Type 0" or "Type 4" diabetes? ... A good example ... is Halle Berry. She was a ... diabetic ... misdiagnosed ... A true Type 1 diabetic ... I got this off your site. What the heck is this? How to "cure" diabetes? ... For Type 1: WHAT CURES DIABETES… (A) Maintain basal insulin [eg type 1 exogenous / type 2 endogenous] to prevent ketoacidosis [pH > 7.2] ... Note for Nick: ... I for example have Type 1 diabetes, Celiac Disease, Hashimoto's Thyroiditis, antibodies to my adrenals (precursor to Addison's) and multiple food allergies. My mom has Type 1, Hashimoto's, and schizophrenia. My aunt is paralyzed and has Multiple Sclerosis. My uncle has Rheumatoid Arthritis and autoimmune fibrocystic lung disease. My other uncle has schizophrenia. My grandfather had Type 1 and autoimmune Pernicious Anemia. His sister has Rheumatoid Arthritis and his brother schizophrenia ... How can fasting grow back a pancreas in someone ... The result of the disease process is ... metabolic ... Also note that only 0.5% of the population has Type 1 diabetes, and only 1 in 600 kids. Only 5-10% of diabetics are Type 1..."
> 0367 www.tinyurl.com/2uxb99 [Dr Allan Cott]
> Rosenbloom, AL, Giordano, BP: Chronic over-treatment with insulin in children and adolescents. Am J Dis Child 131: 881-885, 1977.
> 0107 www.tinyurl.com/2uj9q7 [Bob@BobRanson.net]

Emailed by Scott King on 28 December 2007
http://www.diabeteshealth.com/

"...Nicholas, I love your participation on our site! Thank you so much ... would like to share with you how we are trying to help folks with diabetes ... thanks! ... scott..."
> 0597 www.tinyurl.com/yr8b95 [Katrina Leskanich]
Douglas Kamerow, US editor of BMJ: Is everything you know wrong?
> 0707 www.tinyurl.com/2x3t6l [dkamerow@bmj.com]
> Somogyi, M: Exacerbation of diabetes by excess insulin action. Am J Med, 26: 169-191, 1959.

Hi anonymous, Sarah, Scott, bird54 & AnyOne else...
Eating less OFTEN and digesting more OFTEN can de-congest the liver, reduce auto-immune disease, reduce brain/nerve glucose insulin resistance [bnGIR], increase peripheral tissue glucose insulin resistance [ptGIR] and CURE diabetes.

> The main avoidable CAUSE of diabetes and way to CURE diabetes is set out in the comments & associated links above and in a more concentrated format as follows...

Eating less OFTEN cures type 2 diabetes and eating less OFTEN, even more OFTEN, cures type 1 diabetes.

WATer CURES DIABETES…

(A) Maintain maximum comfortable hydration [drinking / naso-gastic] and minimum/zero basal insulin [eg type 1 exogenous / type 2 endogenous] to prevent ketoacidosis [pH > 7.1] ie the hourly target is pH control in the range 7.2 - 7.5 and plasma blood glucose concentration above 150 mg/dL (9 mmol/L) and within 350 mg/dL (19 mmol/L) of your glucose urination threshold to minimize/prevent any possibility of relative-HYPOglycemia.
> 0108 www.tinyurl.com/39dbyo [rosenal@peds.ufl.edu]
> 0100 www.tinyurl.com/ypozqv [rosenal@peds.ufl.edu]
Beta-cells continue healthy function even at 30 mmol/l or 540 mg/dL
> 0907 www.tinyurl.com/2vrn55 [pbutler@mednet.ucla.edu]
www.en.wikipedia.org/wiki/PH
www.en.wikipedia.org/wiki/Acidosis
www.en.wikipedia.org/wiki/Diabulimia
www.en.wikipedia.org/wiki/Diabetic_ketoacidosis

SUB-15 MEAL

(B) Eat not less but less OFTEN … specifically one meal a day [or less] but always within sub15 minutes … Eat JUST clean water [zero% carbohydrate] between meals [selected to maintain pH above 7.1] & eat ONLY when your blood plasma glucose concentration [PGc] level, following your previous 'nutritionally focussed' eat, has naturally reduced to your chosen baseline blood glucose level [eg below 500 mg/dL (28 mmol/L) and as related to the relative fuel demands of your particular daily activity level] and consciously helping your body learn this habit, of 'supply & demand' glucose control, makes your cure sustainable c/o daily optimizing / increasing peripheral tissue glucose insulin resistance [ptGIR].
> 1107 www.tinyurl.com/2u88dx [mattsonm@grc.nia.nih.gov]
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
> 0501 www.tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]

TYPE 1 BECOMES TYPE 2 BECOMES TYPE 0

(C) Await daily recovery [to relatively lower plasma glucose concentrations], every day better in every way, sustainable, in respect of your increased reduction of relative-HYPOglycemia ie increasingly efficient reduction of the CAUSE [of 'compensatory-HYPERglycemia'] … increasingly efficiently facilitates the gradual recovery your beta-cells & brain/nerve insulin sensitivity … ie gradually towards the total sustainable cure [days/weeks/months for type 1a & type 1.5 … or … hours/days/weeks for type 1b & type 2]. Type 1 CURE by increasing peripheral tissue glucose insulin resistance [ptGIR] ie by transiently acquiring the protective characteristics of a type 2 Diabetic and/or a type 0 [aka pre-Diabetic] and/or type 4 [aka pregnant Diabetic] wherein that ptGIR helps route fuel to to the brain ... gradually eradicating issues of relative-HYPOglycemia EG as recently experienced by BetterCell. Increased peripheral tissue glucose insulin resistance [ptGIR] provides more reliable brain/nerve glucose 'fuel efficiency' at lower plasma glucose concentrations [PGc].
> 1207 www.tinyurl.com/2k6979 [BetterCell.blogspot.com]
www.DiabetesHealth.com/read/2007/11/02/5548.html
> 1007 tinyurl.com/3aypqg [mristow@mristow.org]
> Somogyi, M, Kirstein, M: Insulin as a cause of extreme hyperglycemia and instability. Week Bull St Louis M Soc 32: 498, 1938.
> 0503 www.tinyurl.com/ys63gk [anson@jhu.edu]

In respect of ALL the opinions included within & associated with this comment ... please AnyOne ... ALSO ask your current Specialist for advice, including the provision of supporting Peer reviewed references, evidencing their understanding of this important matter.
> 1207 www.tinyurl.com/2vp4e9 [DrBernarr@aol.com]

…Warm thanks & AdrenalinLove :)
Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ FRI.28.DEC.2007 @ 23:45hrs (C) "I-Fast-23hours-45minutes-EveryDay-OrMore".

Eating less OFTEN is profoundly more healthy than eating less...

> 0400 www.tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
> 0501 www.tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
> 0503 www.tinyurl.com/ys63gk [anson@jhu.edu]
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
> 1007 tinyurl.com/3aypqg [mristow@mristow.org]
www.DiabetesHealth.com/read/2007/12/19/5575.html
www.DiabetesHealth.com/read/2007/12/03/5558.html
www.DiabetesHealth.com/read/2007/11/29/5564.html
www.DiabetesHealth.com/read/2007/11/27/5541.html
www.DiabetesHealth.com/read/2007/11/02/5548.html
> 0108 www.tinyurl.com/39dbyo [rosenal@peds.ufl.edu]
> 1207 www.tinyurl.com/2k6979 [BetterCell.blogspot.com]
> 1207 www.tinyurl.com/27pwj8 [saskiananette@hotmail.com]
> 1207 www.tinyurl.com/3au3a5 [LoveDiabetes.com]
> 1207 www.tinyurl.com/2v9ajm [LoveDiabetes.com]
> 1107 www.tinyurl.com/2u88dx [mattsonm@grc.nia.nih.gov]
> 1107 www.tinyurl.com/yrr5kd [LoveDiabetes.com]
> 1107 www.tinyurl.com/2gxkqt [Mercola.com]
> 1107 www.tinyurl.com/ytm65u [carolyn_susma@bpost.com]
> 1107 www.tinyurl.com/37fh3g [ConditioningResearch.blogspot.com]
> 1007 www.tinyurl.com/35mnkk [Ian Clark]
Beta-cells continue healthy function even at 30 mmol/l or 540 mg/dL
> 0907 www.tinyurl.com/2vrn55 [pbutler@mednet.ucla.edu]
Douglas Kamerow, US editor of BMJ: Is everything you know wrong?
> 0707 www.tinyurl.com/2x3t6l [dkamerow@bmj.com]
> 0607 www.tinyurl.com/2v2pyx [malcolm@llp.org.uk]
http://www.TheDiabetesBlog.com/2007/04/19/no-food-no-problem
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
www.DiabetesHealth.com/read/2007/04/11/5113.html
http://www.TheDiabetesBlog.com/2007/04/03/the-honeymoon-period
> 0107 www.tinyurl.com/2uj9q7 [Bob@BobRanson.net]
> 0107 www.tinyurl.com/2eyxy3 [john.wahren@ki.se]
> 0107 www.tinyurl.com/2farm9 [temorgan@usc.edu]
> 1206 www.tinyurl.com/y7znor [hmdosch@sickkids.ca]
> 0806 www.tinyurl.com/23x2nv [vbhatia@sgpgi.ac.in]
> 0103 www.tinyurl.com/2rh6fz [hmdosch@sickkids.ca]
> 0802 www.tinyurl.com/2qxuzh [Fortunato.Lombardo@unime.it]
> 0101 www.tinyurl.com/2r293z [nsglaser@ucdavis.edu]
> 0100 www.tinyurl.com/ypozqv [rosenal@peds.ufl.edu]
> 0597 www.tinyurl.com/yr8b95 [Katrina Leskanich]
> 0187 www.tinyurl.com/329umr [hans.lithell@pubcare.uu.se]
> Rosenbloom, AL, Giordano, BP: Chronic over-treatment with insulin in children and adolescents. Am J Dis Child 131: 881-885, 1977.
> 0367 www.tinyurl.com/2uxb99 [Dr Allan Cott]
> Somogyi, M: Exacerbation of diabetes by excess insulin action. Am J Med, 26: 169-191, 1959.
> Somogyi, M, Kirstein, M: Insulin as a cause of extreme hyperglycemia and instability. Week Bull St Louis M Soc 32: 498, 1938.
> www.en.wikipedia.org/wiki/PH
> www.en.wikipedia.org/wiki/Acidosis
> www.en.wikipedia.org/wiki/Diabulimia
> www.en.wikipedia.org/wiki/Diabetic_ketoacidosis
> www.en.wikipedia.org/wiki/Michael_Somogyi
> www.en.wikipedia.org/wiki/Image:Somogyi_rebound.GIF
> www.en.wikipedia.org/wiki/Parkinson%27s_disease
> www.en.wikipedia.org/wiki/Leukocytosis
> www.HealSelf.org/Alzheimer's%20Disease.html
> www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]

Eating less OFTEN can CURE any diabetes

Posted by bird54 on 29 December 2007

Hi Nick,
It makes sense that eating one meal a day will benefit an overweight type 2 diabetic, but what about an underweight diabetic who needs more calories? Or what about an underweight non-diabetic teenager with Celiac disease (my son)who needs every extra bite of food just to stay alive?
In one of your comments, you referred to a link where fasting improved the symptoms of people with autoimmune diseases, but when they were put back on food (vegan diet) their symptoms returned. If fasting (eating less often) "cures" autoimmune diseases, then the symptoms should not return upon re-feeding. Perhaps, fasting (eating less often) does not cure diseases but only improves it when the offending foods are removed for a period of time.
What will happen to me if I continue to fast until I reach my ideal weight? At what point will I need to eat more often to maintain weight?

Posted by Nicholas Dynes Gracey on 29 December 2007

Posted by Nicholas Dynes Gracey on 23 December 2007

Sing the 'self-care' song 'CURE' for ALL type 1 & type 2 Diabetics ...

"I-eat-less-OFTEN-
I-fast-more-OFTEN"

Posted by BillyWarhol on 22 December 2007
> www.tinyurl.com/2rv87z [LoveDiabetes.com]

'... Hey Nicholas!

I wanted to personally Thank U for pulling all this Info together for Everybody!

I just clicked on 1 Link the SickKids.ca one + interestingly it was that Headline that Screamed Diabetes Breakthrough at me from the Cover of the National Post Newspaper just over a Year ago*

> 1206 www.tinyurl.com/y7znor [hmdosch@sickkids.ca]

Needless to say I thought Finally they've got the ... CURE!!

Alas they had Cured Mice + also found an Important Trigger to the Sensory Nerves that causes Diabetes*

"Suspecting a link between the nerves and diabetes, he and Dr. Salter used an old experimental trick -- injecting capsaicin, the active ingredient in hot chili peppers, to kill the pancreatic sensory nerves in mice that had an equivalent of Type 1 diabetes.

"Then we had the biggest shock of our lives," Dr. Dosch said. Almost immediately, the islets began producing insulin normally "It was a shock ? really out of left field, because nothing in the literature was saying anything about this."

It turns out the nerves secrete neuropeptides that are instrumental in the proper functioning of the islets. Further study by the team, which also involved the University of Calgary and the Jackson Laboratory in Maine, found that the nerves in diabetic mice were releasing too little of the neuropeptides, resulting in a "vicious cycle" of stress on the islets.

So next they injected the neuropeptide "substance P" in the pancreases of diabetic mice, a demanding task given the tiny size of the rodent organs. The results were dramatic.

The islet inflammation cleared up and the diabetes was gone. Some have remained in that state for as long as four months, with just one injection.

They also discovered that their treatments curbed the insulin resistance that is the hallmark of Type 2 diabetes, and that insulin resistance is a major factor in Type 1 diabetes, suggesting the two illnesses are quite similar."

...

Thanks Again Nicholas for Sharing this Info with us!

;)

Peace* ...'

Hi BillyWarhol & AnyOne else...
Your thanks are acknowledged & most appreciated.

If AnyOne wants the CURE for type 1 & type 2 diabetes then here it is...

First accept the role of inflammation as part of the CAUSE and then remove that inflammation.

Here's how ...

ONE MEAL A DAY

By consciously & repeatedly, over & over, singing the 'self-care' song ... "I-eat-less-OFTEN-I-fast-more-OFTEN"
... it is increasingly possible, for these lyrics, to train your subconscious mind to better AND better enjoy 1 meal a day [or less] and every day better in every way ... train your body's metabolism to enter into 'healing ketosis' increasingly quickly.
> www.en.wikipedia.org/wiki/%C3%89mile_Cou%C3%A9
> www.en.wikipedia.org/wiki/Ketosis
> 0503 tinyurl.com/ys63gk [anson@jhu.edu]
> 1107 www.tinyurl.com/2u88dx [mattsonm@grc.nia.nih.gov]

REMOVING THE CAUSE

The CAUSE of type 1 diabetes was first published as early as 1938 by Dr Michael Somogyi. Somogyi found that the liver produced above-average plasma glucose concentration aka type 1 or type 2 diabetes ... as a protective safety mechanism to prevent a loss of consiousness following a HYPOglycemic threat to the brain/nerves.
> www.en.wikipedia.org/wiki/Chronic_Somogyi_rebound

As insulin 'pumps' plasma glucose concentration, too quickly, into fat, liver & muscle cells ... there is too little left for the brain. The brain instructs Transient Supernormal Glycemia [TSG aka HYPERglycemia aka diabetes] from your LIVER and the diabetes produced ... saves your life.

It's time to love diabetes for what it REALLY is.

HYPOglycemic foods, HYPOglycemic drugs & HYPOglycemic distresses ALL stimulate Diabetic TSG from your LIVER, by your brain, as a protective adaptive reaction to keep You ALIVE.
> www.en.wikipedia.org/wiki/Image:Somogyi_rebound.GIF

Every time You eat 1 meal a day You can create an amount of islet cell inflammation ... inflammatory to the extent that a HYPOglycemic chemical, EG ... GM insulin, reduces your plasma glucose concentration [PGc] down far too quickly ... ie your choice of meal creates a rise in PGc and the subsequent HYPOglycemic chemical, reducing PGc too quickly, leads to protective islet inflammation and protective reduced islet activity ... ie to protect against the islets contributing extra HYPOglycemic insulin which could result in an extraordinary excessive reduction in PGc and potentially even more of a challenging DISTRESS to the brain/nerves.
> www.en.wikipedia.org/wiki/Diabetic_hypoglycemia

If You choose to eat 1 small meal only ... and choose foods that minimize any HYPERglycemic response resulting from the post-meal HYPOglycemic chemical ... Every day Better in every way ... your beta-cell inflammation will be relieved & recover ... especially rapidly if You choose to eat a low or sub15 % carbohydrate meal.
> 0102 www.tinyurl.com/2po68s [duvillie@necker.fr]

How quickly You choose to cure type 1 diabetes is up to You. Its all related to your focus upon reducing the numerous daily [inflammatory] HYPOglycemic threats, from multiple times daily, to ZERO ... every day better in every way.
> www.en.wikipedia.org/wiki/Hypoglycemia

IE diabetes is NOT a disease ... diabetes is a protective safety mechanism to protect the brain/nerves from being daily starved of glucose.
> www.tinyurl.com/2459gp [Neuro-Glyco-Penia]

In type 1 the HYPOglycemic danger is greater because of the presence of extra HYPOglycemic chemicals such as growth hormone [eg in Children & Athletes]. In type 1 the greater HYPOglycemic danger creates inflammation coupled with a safety switching off of the beta-cells to help maintain consciousness following a meal associated rise in insulin.
> www.en.wikipedia.org/wiki/Michael_Somogyi

THE CURE FOR TYPE 1 DIABETES

Diabetics [type 1 & type 2] and other healthy People should test daily with ChemStrips and pause from eating, reducing insulin to basal sufficient to maintain pH 7.1 or more, and all day every day, better in every way, drink just clean [EG filtered] water, until their urine is glucose free. If more than 23 hours 45 minutes has passed since the previous meal ... and there is still glucose in the urine ... a sub15% carbohydrate meal should be chosen and should be as small as possible [and preferably raw food to minimise leukocytosis] ... all food selected for nutritional value ... and ... to minimise a rise in plasma glucose concentration [as per that Individuals experience with particular foodstuffs]. The less carbohydrate eaten ... the less HYPOglycemic threat ... the quicker the reduction of inflammation [apoptosis] and associated quicker recovery [regeneration] of beta-cell function.
> 0407 tinyurl.com/29kvda [zangend@hadassah.org.il]
> www.TheDiabetesBlog.com/2007/04/19/no-food-no-problem
> www.en.wikipedia.org/wiki/The_Optimal_Diet
> 1206 www.tinyurl.com/y7znor [hmdosch@sickkids.ca]
> www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]

That is how to CONTROL & CURE type 1 & type 2 'diabetes' AND prevent all 'newly diagnosed' type 1 & type 2 diabetes.
> www.en.wikipedia.org/wiki/Apoptosis
> www.en.wikipedia.org/wiki/Regeneration_%28biology%29
> www.en.wikipedia.org/wiki/Leukocytosis
> 0130 www.tinyurl.com/ynojqw [Paul Kouchakoff's raw food]

GLUCOSE PRODUCTION ON-DEMAND

By fueling the body, increasingly on ketones, the LIVER can better focus upon gluconeogenesis for supplying an efficient flow of glucose ... out of the liver and into the plasma ... to increase the blood plasma glucose concentration [PGc] ... specifically to help fuel the brain & nerves especially during times of stress & distress.
> www.en.wikipedia.org/wiki/Gluconeogenesis
> 0103 www.tinyurl.com/yszb9q [rortiz1@tulane.edu]

KETOGENIC DIETS HELP

Ketogenic diets, like 1 meal a day, can help any Diabetic to gently & naturally, reduce their post-meal glucose concentration [PGc] 'slowly & surely' ... which is very beneficial ... because ... since JAN.1966 [and before] it has been proven that relative-HYPOglycemia can result from 'too quick' a reduction of PGC ... resulting in the following neuro-psychiatric symptoms as the body is distressed into 'corrective' methods of preventing nerve/brain tissue from switching-off and/or 'flickering' from the effects of subsequent ... too rapidly reduced cerebral glucose concentration [CGc] aka brain/nerve 'glucose starvation' aka Neuro-Glycopenia ... aka ... the 'Neuro-Glycemic-bends' [NGb] ...

Depression, Insomnia, Anxiety, Irritability, Crying Spells, Phobias, Lack of Concentration, Forgetfulness or Confusion, Unsocial or Antisocial Behavior, Restlessness, Psychosis, Suicidal Behavior; Exhaustion or Fatigue, Sweating, Tachycardia, Anorexia, Chronic Indigestion or Bloating, Cold Hands or Feet, Joint Pains, Obesity, Abdominal Spasm; Headache, Dizziness, Tremor [inward or external], Muscle Pains & Backache, Numbness, Blurred Vision, Muscular Twitching or Cramps, Staggering, Fainting or Blackouts and also Convulsions.
> 0166 'Relative-HYPOglycemia As A Cause Of Neuropsychiatric Illness' @ Journal Of The National Medical Association @ Harry M Salzer MD @ January 1966 @ Vol 58 @ Number 1 @ Table 1 @ Figure 2.

DIABETES FEEDS your BRAIN

http://orthomolecular.org/library/jom/1999/pdf/1999-v14n01-p023.pdf

' ... Because the cerebral glucose concentration [CGc] approaches zero when plasma glucose concentration [PGc] decreases to below 40 mg/dL, 'blood glucose' PGc should be maintained above this level....'
> 1203 www.tinyurl.com/39zu9o [Lori A Markham]

Evidence suggests that being ANYdrugTREATED less OFTEN ... better AND better MORE slowly & naturally reduces blood plasma glucose concentration [PGc], having consequential positive effects upon [brain/nerve] cerebro-spinal glucose concentration [CGc] ... comparable to giving a deep sea Diver time to avoid 'the bends' by too physiologically-quick 'an ascent' ... avoiding 'the glycemic bends', too physiologically-quick 'a descent', can have very positive effects upon Diabetics including all manner of relative-HYPOglycemia associated symptoms.
> www.tinyurl.com/23akqw [Relative-HYPOglycemia]
> www.en.wikipedia.org/wiki/Non-epileptic_seizure
> 0704 www.tinyurl.com/2xx6ps [JML@biostat.bsc.gwu.edu]
> 0124 "Hyperinsulinism and Dysinsulinism" @ J.A.M.A @ Seale Harris @ 1924 @ Vol 83 @ page 729-733.

Less OFTEN ANYdrugTREATED
FOR better AND better WEIGHT CONTROL

'... Weight gain was a problem with intensive therapy, with an increase of 33 percent in the mean adjusted risk of becoming overweight, a condition defined as a body weight more than 120 percent above the ideal [12.7 cases of overweight per 100 patient-years in the intensive-therapy group vs. 9.3 in the conventional-therapy group]. At five years, patients receiving intensive therapy had gained a mean of 4.6 kg more than patients receiving conventional therapy...'
> 0993 www.tinyurl.com/2xbcs8 [DCCT 1993]
> 1188 www.tinyurl.com/2mcvz8 [DCCT 1988]
> 0178 www.tinyurl.com/33q5rt [ndic@info.niddk.nih.gov]

Less OFTEN ANYdrugTREATED
FOR better AND better EYES & KIDNEYS

'... Why some cases of retinopathy worsen when diabetic control improves ... the rate of fall of blood glucose concentration and the accompanying reduction in blood flow have been thought to be the trigger ... This suggestion was supported by the finding of Grunwald et al, who showed a 20% reduction of blood flow when blood glucose concentrations fell from about 15 mmol/l to 8 mmol/l ... This "Normo-Glycemic re-entry phenomenon" has puzzled clinicians ... and ... there is still much to learn about its mechanism ...'
> 1087 www.tinyurl.com/2d48d5 [juangrun@mail.med.upenn.edu]
> 0297 www.tinyurl.com/yu77y7 [m.henricsson@telia.com]
> 1097 www.tinyurl.com/34lyyj [lobnig@med.uni-duesseldorf.de]

"NORMO-GLYCEMIC re-entry [NGr] PHENOMENON"

'... 3867 newly diagnosed patients with type 2 diabetes, median age 54 years [48–60 years], who after 3 months' diet treatment had a mean of two fasting plasma glucose [FPGc] concentrations of 6·1–15·0 mmol/L, were randomly assigned 'intensive policy' with a sulphonylurea [chlorpropamide, glibenclamide, or glipizide] or with insulin, or 'conventional policy' with diet. The aim in the intensive group was FPGc less than 6 mmol/L. In the conventional group, the aim was the best achievable FPGc with diet alone; HYPOglycemic drugs were added, to rapidly reduce FPGc to 6 mmol/L, only if there were HYPERglycemic symptoms [eg thirst] OR fasting plasma glucose greater than 15 mmol/L...'
> 1098 www.tinyurl.com/38cr65 [Turner UKPDS 33]
> en.wikipedia.org/wiki/Intensive_insulinotherapy
> en.wikipedia.org/wiki/Conventional_insulinotherapy
> www.en.wikipedia.org/wiki/Anti-diabetic_drug

HARRY SALZER & DEBRA FADOOL

Following the significance of Harry Salzer's 1966 breakthrough reference ... Debra Fadool's 2000 reference may well prove to be one of the MOST influential pieces of research ever done, so far, in the field of depression / dementia / Alzheimer's / 'diabetes' [aka above average plasma blood glucose].

"...Our data suggest that there is a clear differential between the levels of insulin in the plasma and that found in the..." brain/nerve tissue.
> 0400 tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]

EAT-less-OFTEN ... MAKE less FAT and/or
WAT STORING beta-cell INSULIN [BCI]

Why do You think that Fadool's 2000 research found that the brain may selectively increase manufacture of more brain/nerve insulin [BNI] at times when pancreatic beta-cell insulin [BCI] manufacture is simultaneously DELIBERATELY reduced ?

And how would an increase in peripheral tissue 'Glucose Insulin Resistance' [GIR aka inflammation] help that DELIBERATE adaption?

CLUE = surface irrigation systems eg still adopted efficiently in Africa.
> www.en.wikipedia.org/wiki/Irrigation
> 0195 www.tinyurl.com/2lb5om [jolefsky@ucsd.edu]

FAST-more-OFTEN ... MAKE more BAT and
BRAIN NERVE INSULIN [BNI]

If the BNI production multiplication factor of increased brain/nerve insulin ... by 72 hours of just drinking water ... can be 15 x 'times' BNI greater [Fadool's 2000 discovery].

What do You speculate may happen to 'brain-POWERing' BNI production with a break-fast/snack/meal at 1 / 3 / 6 / 12 / 18 / 24 / 48 & 96 hours ?
> www.en.wikipedia.org/wiki/Proportionality_(mathematics)
> www.en.wikipedia.org/wiki/Water
> www.en.wikipedia.org/wiki/Fasting
> 0104 www.tinyurl.com/2mdwdb [jan@metabol.su.se]
> 0104 www.tinyurl.com/37doxu [barbara.cannon@wgi.su.se]

EAT-less-OFTEN ... MAKE better AND better
BRAIN NERVE INSULIN [BNI]

What (?) is the probable significance [in relation to the consequences of 'EAT-less-OFTEN' meal frequency] of Fadool's 2000 BREAKTHROUGH discovery that BNI "levels are low after a meal" ... as regards the POSSIBLE better AND better EFFICIENCY of glucose fuel availability to brain/nerve tissue WHEN depression / dementia / Parkinson's / Alzheimer's [aka type 3 Diabetic] Patients / 'mood-swinging Diabetics' ... DECIDE to repeatedly Sing the song ...
"I-eat-less-OFTEN-I-fast-more-OFTEN"
> 0503 www.tinyurl.com/ys63gk [anson@jhu.edu]
> 1004 www.tinyurl.com/2b99ka [mattsonm@grc.nia.nih.gov]
> 0107 www.tinyurl.com/yta44e [giulio.passinetti@mssm.edu]
> 0107 www.tinyurl.com/2farm9 [temorgan@usc.edu]

And under what circumstances, of meal frequency [and/or NGr], would an adaptive increase in brain/nerve tissue 'Glucose Insulin Resistance' [neural GIR aka neural inflammation] be expected and for what reason ?
> 0382 www.tinyurl.com/2f5say [nancy.rothwell@manchester.ac.uk]
> 1206 www.tinyurl.com/y7znor [hmdosch@sickkids.ca]
> 0407 www.tinyurl.com/ynpp4g [raymond.swanson@ucsf.edu]
> 1007 www.tinyurl.com/3aypqg [mristow@mristow.org]

REMEMBER THE better AND better EVIDENCE
IS THAT ABOVE-AVERAGE 'BLOOD GLUCOSE'
IS HEALTHIER THAN any ARTIFICIAL LOWERING

PLEASE click on the following 2 web links ASAP and comment ASAP upon your current opinion / preference as to 1 or other of these 2 physiological 'conditions' ...
> www.en.wikipedia.org/wiki/Hypoglycemia
> www.en.wikipedia.org/wiki/Hyperglycemia

Plasma blood glucose [PGc] concentrations depend upon the level of water HYDRATION concentration and are measured in either:

1. Milligrams per deciliter (mg/dL), in the United States and other countries (e.g. Japan, France, Egypt, Colombia); or

2. Millimoles per liter (mmol/L), which can be acquired by dividing (mg/dL) by factor of 18.

Scientific journals are moving towards using mmol/L; some journals now use mmol/L as the primary unit but quote also mg/dl.

Comparatively:

* 72 mg/dL = 4 mmol/L
* 90 mg/dL = 5 mmol/L
* 108 mg/dL = 6 mmol/L
* 126 mg/dL = 7 mmol/L
* 144 mg/dL = 8 mmol/L
* 180 mg/dL = 10 mmol/L
* 270 mg/dL = 15 mmol/L
* 288 mg/dL = 16 mmol/L
* 360 mg/dL = 20 mmol/L
* 396 mg/dL = 22 mmol/L
* 594 mg/dL = 33 mmol/L

BETA CELLS SWITCH-OFF AND TURN-ON

Beta Cells continue healthy function even at 30 mmol/l or 540 mg/dL
> 0907 www.tinyurl.com/2vrn55 [pbutler@mednet.ucla.edu]
> 1206 www.tinyurl.com/y7znor [hmdosch@sickkids.ca]
> 0907 www.tinyurl.com/2vwnlg [yuvald@ekmd.huji.ac.il]
> 0506 www.tinyurl.com/2542a6 [stephane.dalle@igf.cnrs.fr]
> 0306 www.tinyurl.com/yw3lzz [seino@med.kobe-u.ac.jp]

In respect of ALL the opinions included within this comment ... please AnyOne ... ALSO ask your current Specialist for advice including the provision of supporting Peer reviewed references evidencing their understanding of this important matter.
> 1207 www.tinyurl.com/2vp4e9 [DrBernarr@aol.com]

…Warm thanks; Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ SUN.23.DEC.2007 @ 23:32hrs (C) "I-eat-less-OFTEN-I-fast-more-OFTEN".

Eating less OFTEN is profoundly more healthy than eating less...
> www.tinyurl.com/23akqw [Relative-HYPOglycemia]
> 0400 tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
> 0501 tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
> 0503 tinyurl.com/ys63gk [anson@jhu.edu]
> 0407 tinyurl.com/29kvda [zangend@hadassah.org.il]
> 1007 tinyurl.com/3aypqg [mristow@mristow.org]
> www.DiabetesHealth.com/read/2007/12/19/5575.html
> www.DiabetesHealth.com/read/2007/12/03/5558.html
> www.DiabetesHealth.com/read/2007/11/29/5564.html
> www.DiabetesHealth.com/read/2007/11/27/5541.html
> www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]
> www.HealSelf.org/Alzheimer's%20Disease.html
> www.en.wikipedia.org/wiki/Water
> www.en.wikipedia.org/wiki/Thyroid
> www.en.wikipedia.org/wiki/Thymus
> www.en.wikipedia.org/wiki/Surge_protection
> www.en.wikipedia.org/wiki/Sunny_von_B%C3%BClow
> www.en.wikipedia.org/wiki/Proportionality_(mathematics)
> www.en.wikipedia.org/wiki/Pancreas
> www.en.wikipedia.org/wiki/Non-epileptic_seizure
> www.tinyurl.com/2459gp [Neuro-Glyco-Penia]
> www.en.wikipedia.org/wiki/Liver
> www.en.wikipedia.org/wiki/Leukocytosis
> www.en.wikipedia.org/wiki/Ketosis
> www.en.wikipedia.org/wiki/Irrigation
> www.tinyurl.com/3d72fl [Insulin-like Growth Factor]
> www.en.wikipedia.org/wiki/Intensive_insulinotherapy
> www.en.wikipedia.org/wiki/Conventional_insulinotherapy
> www.en.wikipedia.org/wiki/Insulin
> www.en.wikipedia.org/wiki/Hypoglycemia
> www.en.wikipedia.org/wiki/Hyperglycemia
> www.en.wikipedia.org/wiki/HbA1c
> www.en.wikipedia.org/wiki/Gluconeogenesis
> www.en.wikipedia.org/wiki/Glucagon
> www.en.wikipedia.org/wiki/Fasting
> www.en.wikipedia.org/wiki/Diabetic_hypoglycemia
> www.tinyurl.com/2dm4b9 [Continuous Glucose Monitoring]
> www.en.wikipedia.org/wiki/Chronic_Somogyi_rebound
> www.en.wikipedia.org/wiki/Certified_diabetes_educator
> www.en.wikipedia.org/wiki/Cerebrospinal_fluid
> www.en.wikipedia.org/wiki/C-peptide
> www.en.wikipedia.org/wiki/%C3%89mile_Cou%C3%A9
> www.en.wikipedia.org/wiki/Anti-diabetic_drug
> 1207 www.tinyurl.com/24nktv [LoveDiabetes.com]
> www.tinyurl.com/3buzxn [Suzanne_DeLaMonte_MD@Brown.edu]
> 1207 www.tinyurl.com/2k6979 [BetterCell.blogspot.com]
> 1207 www.tinyurl.com/2vp4e9 [DrBernarr@aol.com]
> 1207 www.tinyurl.com/29udcr [carol.johnston@asu.edu]
> 1207 www.tinyurl.com/3x9qh6 [ScienceDaily.com]
> 1107 www.tinyurl.com/2u88dx [mattsonm@grc.nia.nih.gov]
> 1107 www.tinyurl.com/2nvcqv [brancori@terra.com.br]
> 1007 www.tinyurl.com/3aypqg [mristow@mristow.org]
> 1007 www.tinyurl.com/3bcr7h [LoveDiabetes.com]
Beta Cells continue healthy function even at 30 mmol/l or 540 mg/dL
> 0907 www.tinyurl.com/2vrn55 [pbutler@mednet.ucla.edu]
> 0907 www.tinyurl.com/2vwnlg [yuvald@ekmd.huji.ac.il]
> 0807 www.tinyurl.com/24e67s [Matthew.Sadgrove@duke.edu]
Douglas Kamerow, US editor of BMJ: Is everything you know wrong?
> 0707 www.tinyurl.com/2x3t6l [dkamerow@bmj.com]
> 0607 www.tinyurl.com/2v2pyx [malcolm@llp.org.uk]
Andrew Farmer: Why monitor PGc of type 2 on oral med?
> 0607 www.tinyurl.com/yuwm8w [andrew.farmer@dphpc.ox.ac.uk]
> 0407 www.tinyurl.com/yog6oe [sm87j@nih.gov]
> 0407 www.tinyurl.com/2mffcj [zinman@mshri.on.ca]
> 0407 www.tinyurl.com/ynpp4g [raymond.swanson@ucsf.edu]
> www.TheDiabetesBlog.com/2007/04/19/no-food-no-problem
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
> 0307 www.tinyurl.com/2v3lxs [LoveDiabetes.com]
> 0307 www.tinyurl.com/yqmqnj [Kauffman@hslc.org]
> 0307 www.tinyurl.com/28lr3g [barbara.cannon@wgi.su.se]
> 0107 www.tinyurl.com/yta44e [giulio.passinetti@mssm.edu]
> 0107 www.tinyurl.com/yuh3q8 [mattisonj@mail.nih.gov]
> 0107 www.tinyurl.com/378bwo [martin.rutter@coch.nhs.uk]
> 0107 www.tinyurl.com/2farm9 [temorgan@usc.edu]
> 0107 www.tinyurl.com/2eyxy3 [john.wahren@ki.se]
> 1206 www.tinyurl.com/y7znor [hmdosch@sickkids.ca]
> 1106 www.tinyurl.com/2bn2g7 [carol.johnston@asu.edu]
> 1006 www.tinyurl.com/2hnp9h [lmr@dadlnet.dk]
> 0906 www.tinyurl.com/yuqqes [Mark Mayer]
> 0906 www.tinyurl.com/2jh8cj [MayoClinic.com]
> 0506 www.tinyurl.com/2542a6 [stephane.dalle@igf.cnrs.fr]
> 0306 www.tinyurl.com/yw3lzz [seino@med.kobe-u.ac.jp]
> 1204 www.tinyurl.com/2gcjdn [francesca_messina@yahoo.it]
> 1004 www.tinyurl.com/2b99ka [mattsonm@grc.nia.nih.gov]
> 0904 www.tinyurl.com/7ggyq [carol.johnston@asu.edu]
> 0704 www.tinyurl.com/2xx6ps [JML@biostat.bsc.gwu.edu]
> 0104 www.tinyurl.com/2mdwdb [jan@metabol.su.se]
> 0104 www.tinyurl.com/37doxu [barbara.cannon@wgi.su.se]
> 1203 www.tinyurl.com/39zu9o [Lori A Markham]
> 0903 www.tinyurl.com/2owwsn [skarch@sonic.net]
> 0803 www.tinyurl.com/2tp6vo [efeldman@umich.edu]
> 0503 www.tinyurl.com/ys63gk [anson@jhu.edu]
> 0103 www.tinyurl.com/2arzxs [DiabetesCaseStudy.com]
> 0103 www.tinyurl.com/yszb9q [rortiz1@tulane.edu]
> 0103 www.tinyurl.com/2rh6fz [hmdosch@sickkids.ca]
> 0402 www.tinyurl.com/2e8uw7 [joy.dauncey@bbsrc.ac.uk]
> 0202 www.tinyurl.com/2rhf7p [Robert R. Barefoot]
> 0501 www.tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
> 0400 www.tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
http://orthomolecular.org/library/jom/1999/pdf/1999-v14n01-p023.pdf
> 1098 www.tinyurl.com/38cr65 [Turner UKPDS 33]
> 1197 www.tinyurl.com/34lyyj [lobnig@med.uni-duesseldorf.de]
> 0297 www.tinyurl.com/yu77y7 [m.henricsson@telia.com]
> 0195 www.tinyurl.com/2lb5om [jolefsky@ucsd.edu]
> 0993 www.tinyurl.com/2xbcs8 [DCCT 1993]
> 0491 www.tinyurl.com/2eqls2 [DCCT 1991]
> 1188 www.tinyurl.com/2mcvz8 [DCCT 1988]
> 1287 www.tinyurl.com/2d48d5 [juangrun@mail.med.upenn.edu]
> 0382 www.tinyurl.com/2f5say [nancy.rothwell@manchester.ac.uk]
> 0178 www.tinyurl.com/33q5rt [ndic@info.niddk.nih.gov]
> 0166 'Relative-HYPOglycemia As A Cause Of Neuropsychiatric Illness' @ Journal Of The National Medical Association @ Harry M Salzer MD @ January 1966 @ Vol 58 @ Number 1 @ Table 1 @ Figure 2.
> 0124 "Hyperinsulinism and Dysinsulinism" @ J.A.M.A @ Seale Harris @ 1924 @ Vol 83 @ page 729-733.

Posted by Nicholas Dynes Gracey on 30 December 2007

Quotation by Herbert M Shelton on December 1978

"...Food and nutrition are NOT synonymous. You are not nourished by the food that you eat, but in proportion to the amount you DIGEST and ASSIMILATE..."

One meal a day, appropriately structured, can help shed fat and/or build muscle depending upon associated exercise [eg aerobic/anaerobic] and/or nutrition [eg carb %].
> 1107 www.tinyurl.com/2u88dx [mattsonm@grc.nia.nih.gov]
> www.en.wikipedia.org/wiki/Sarcopenia
> www.en.wikipedia.org/wiki/Coeliac_disease
> www.HealSelf.org/Colitis.html

Posted by BillyWarhol on 22 December 2007
> www.tinyurl.com/2rv87z [LoveDiabetes.com]

'... Hey Nicholas! I wanted to personally Thank U for pulling all this Info together for Everybody! I just clicked on 1 Link the SickKids.ca one + interestingly it was that Headline that Screamed Diabetes Breakthrough at me from the Cover of the National Post Newspaper just over a Year ago*
> 1206 www.tinyurl.com/y7znor [hmdosch@sickkids.ca]

Needless to say I thought Finally they've got the ... CURE!!
"Then we had the biggest shock of our lives," Dr. Dosch said. Almost immediately, the islets began producing insulin normally "It was a shock ... really out of left field, because nothing in the literature was saying anything about this ... The results were dramatic ... The islet inflammation cleared up and the diabetes was gone ... They also discovered that their treatments curbed the insulin resistance that is the hallmark of Type 2 diabetes, and that insulin resistance is a major factor in Type 1 diabetes, suggesting the two illnesses are quite similar."
Thanks Again Nicholas for Sharing this Info with us!
;)
Peace* ...'

Posted by bird54 on 29 December 2007
> 1207 www.tinyurl.com/28zphn [LoveDiabetes.com]

'... Nick, you are a tremendous resource to me with all your links. For the past 2 years I have been reading every book I could find about diabetes, in addition to searching the web for information, but I have learned more in a short time from reading your comments than anything else ... My teenage son has Coeliac disease and multiple food allergies. I think he has adrenal fatigue/exhaustion too, because he cannot handle any amount of stress. He is on a very restricted diet, takes digestive enzymes, but still has bloating after meals. While I fast daily to lose weight and control my type 2 diabetes, I would not put him on a fast for fear that he will shrivel up and blow away. He is already extremely underweight and I cannot risk him losing any more.
I really sympathize with type 1 diabetics who have to inject insulin just to stay alive. I have a hard enough time controlling my type 2 diabetes with diet and exercise. The shocker for me was that I got diabetes even though it does NOT run in my family (although I suspect my grandmother may have had gestational diabetes because of her large babies). I always exercised and ate right, and yet I got diabetes anyway. For no known reason, I just started gaining weight and then one day I had diabetes. Low carb dieting and exercise does not take off the pounds. It just maintains my weight. However, fasting puts me into mild ketosis and then I lose weight. Being a former champion gymnast, it disgusts me to look in the mirror and not see the lean, muscular body I once possessed. It is not easy for anyone to live with diabetes...'

'...It is clear to me that "inflammation" is the cause of all diseases, including diabetes. It seems that food intolerances/allergies may be the culprit that causes inflammation. Avoiding the trigger foods (gluten, casein, eggs, nuts, soy, etc.) can reduce inflammation. Fasting also helps because it means less exposure to the trigger foods, plus giving the body time to detox. So I think that Nick is on to something here...'

'...Before I developed type 2 diabetes, I had a period of several years where my weight started to creep up. I went on Atkin's and lost weight. People kept telling me, "Don't go on Atkin's or you will have a heart attack!" So I took the advice of people who convinced me that I needed more "whole grains". I started eating whole wheat bread, and guess what? Within 3 months I had diabetes. Recently, I went to an allergy specialist who told me that I am allergic to milk and wheat. I wonder if the reason these grainless, low carb diets work is because many people are sensitive to gluten...'

Hi bird54, BillyWarhol, BetterCell, Brent & AnyOne else...
Eating less OFTEN and digesting more OFTEN can de-congest the liver, reduce auto-immune disease, reduce brain/nerve glucose insulin resistance [bnGIR], increase peripheral tissue glucose insulin resistance [ptGIR] and CURE diabetes.
> www.en.wikipedia.org/wiki/Liver

The main avoidable CAUSE of diabetes and way to CURE diabetes is set out in the comments & associated links above and in a more concentrated format as follows...

Eating less OFTEN cures type 2 diabetes and eating less OFTEN, even more OFTEN, cures type 1 diabetes.

Lithell's 1983 chronic inflammation reference relates to the fasting referred to by your comment BUT that type of fasting / aka digestion is without any mention of the word "OFTEN" and therefore lacks the SUSTAINABILITY of 'better digestion associated benefits' of eating less OFTEN aka intermittent eating / intermittent fasting.
> 0183 www.tinyurl.com/329umr [hans.lithell@pubcare.uu.se]

INTERMITTENT EATING

The difference between eating / fasting vs intermittent eating & intermittent fasting is that the results of an intermittent system are sustainable. EG sustainable to achieve relief from inflammation and/or sustainable to the stage of a complete CURE. Its a matter of time & effort ... like training to be a champion gymnast or intermittent exercising ... every day better in every way ... in order to make SUSTAINABLE progress.

Coeliac disease needs an intermittent eating & intermittent exercising system that ... every day better in every way ... reduces excess inflammation and builds increased muscle mass. A fast way [in my opinion] to achieve that is ... one meal a day [or less] of EXCLUSIVELY "fresh organic raw liquidiet nutrition" of minimally allergenic juicy water-rich foods [EG fruits / vegetables / raw egg yolks]. Modern technology makes this possible & sustainable. Vast quantities can be enjoyably 'eaten' within 15 minutes ... followed 23 HOURS 45 MINUTES OR MORE of thinking, planning, exercising, digestion & assimilation BEFORE eating again. Consuming 'solid food' in the presence of Coeliac inflammatory disease, on the delicate digestive tissue linings, is out-of-order if there is a healthier alternative.
> www.en.wikipedia.org/wiki/Coeliac_disease
> 1206 www.tinyurl.com/y7znor [hmdosch@sickkids.ca]
> www.en.wikipedia.org/wiki/Juice_fasting
> www.en.wikipedia.org/wiki/Inflammation
> www.en.wikipedia.org/wiki/Lyme_disease

To properly digest & assimilate 1 meal a day various hormones need to be stimulated in the body that will encourage nerve & muscle growth and create an 'assimilation-hunger' within your Son / his tissues.
> www.en.wikipedia.org/wiki/Sarcopenia

In my opinion the world leader in EFFICIENTLY building maximum muscle mass, whilst eating the minimum amount of [inflammation producing] food, is Pete Sisco.
> http://www.getthisstrong.com/ [support@superrepequipment.com]
> www.HealSelf.org/Strong-Become%20Stronger.html [Dr Bernarr]
> http://www.matthewfurey.com/ [zen]
> http://www.mattfurey.com/ [conditioning]

Sustainable weight control is about understanding HOW to shed fat or build muscle. You & your Son should understand what Pete Sisco, Dr Bernarr & Matt Furey are teaching about becoming stronger.

INTERMITTENT EXERCISING

If your Son & Yourself can do a wall-facing-handstand [toes supported by the wall] for more than 5 seconds You can both substantially & sustainably increase muscle mass, every day better in every way, by increasing your record hold-time for holding that 'isometric gymnastic posture' by 5 seconds extra EVERY day.

Please comment on your & your Son's current record posture hold-time and record it daily on a wall somewhere and watch the daily improvement. [You should also measure your pH at least once daily].

Anecdotally a number of TV documentaries feature tribes etc who sustain Themselves with the benefit of 1 meal a day [or less]. The muscle tone and anatomy of the Men, Women & Children is usually extra-ordinarily healthy.
> www.en.wikipedia.org/wiki/Sarcopenia

ALTERNATIVES & CHOICES

Certain diets/mediations owe their 'weight-loss' associations to increased inflammation. You need learn from Pete Sisco how little food is needed to become stronger [eg when growth hormone is sustainably stimulated] and to be courageous for your Son and ASAP secure the support of licensed medical Practitioner who is fit & strong and clearly understands the benefits of ... fresh organic raw liquidiet nutrition ... to digestion, assimilation & 'body-building'; AND please discuss the following intermittent eating / fasting protocol as suitable for both Yourself [low carb] & your Son [high carb] ... reading between the lines in so far as your Son is diabetes/medication free? Details of the Practitioner's feedback / alternative strategy would be most appreciated...
> www.en.wikipedia.org/wiki/Growth_hormone

WATer CURES INFLAMMATION…

(A) Maintain maximum comfortable hydration [drinking / naso-gastic] and minimum [50-75% reduction] basal insulin [eg type 1 exogenous / type 2 endogenous] to prevent ketoacidosis [pH > 7.1] ie the hourly target is pH control in the range 7.2 - 7.5 and plasma blood glucose concentration STRICTLY above 150 mg/dL (9 mmol/L) and below approximately 350 mg/dL (19 mmol/L) which should encourage Diabetic glucose urination of excess plasma glucose concentrations and simultaneously minimize/prevent any possibility of relative-HYPOglycemia [the apparent CAUSE of 'compensatory-HYPERglycemia' / aka diabetes].
> 0108 www.tinyurl.com/39dbyo [rosenal@peds.ufl.edu]
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
> 0100 www.tinyurl.com/ypozqv [rosenal@peds.ufl.edu]
Cerebral cGc is approx 40mg/dL less than Plasma pGc concentration
> 1203 www.tinyurl.com/39zu9o [Lori A Markham]
> www.en.wikipedia.org/wiki/The_Optimal_Diet
> www.en.wikipedia.org/wiki/PH
> www.en.wikipedia.org/wiki/Acidosis
> www.en.wikipedia.org/wiki/Diabulimia
> www.en.wikipedia.org/wiki/Diabetic_ketoacidosis

ONE SUB15 min MEAL EVERY DAY

(B) Eat not less but less OFTEN … specifically one meal a day [or less] but always within sub15 minutes … Eat JUST clean water [zero% carbohydrate] between meals [selected to maintain pH above 7.1 and minimize any allergenic response] & eat ONLY when your blood plasma glucose concentration [pGc] level, following your previous 'nutritionally focussed' eat, has naturally reduced to your chosen baseline plasma glucose range [eg 150 mg/dL (9 mmol/L) to 350 mg/dL (19 mmol/L) and as related to the relative fuel demands of your particular daily activity level] and consciously helping your body learn this habit, of 'supply & demand' glucose control, makes your cure sustainable c/o daily optimizing / increasing peripheral tissue glucose insulin resistance [ptGIR].
> 1107 www.tinyurl.com/2u88dx [mattsonm@grc.nia.nih.gov]
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
> 0501 www.tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
Beta-cells can be healthy even at 30 mmol/l or 540 mg/dL [pH > 7.1]
> 0907 www.tinyurl.com/2vrn55 [pbutler@mednet.ucla.edu]

TYPE 1 BECOMES TYPE 2 BECOMES TYPE 0

(C) Await daily recovery [to relatively lower plasma glucose concentrations], every day better in every way, sustainable, in respect of your increased reduction of relative-HYPOglycemia ie increasingly efficient reduction of the CAUSE [of 'compensatory-HYPERglycemia'] … increasingly efficiently facilitates the gradual recovery your beta-cells & brain/nerve insulin sensitivity … ie gradually towards the total sustainable cure [days/weeks/months for type 1a & type 1.5 … or … hours/days/weeks for type 1b & type 2]. Type 1 CURE by increasing peripheral tissue glucose insulin resistance [ptGIR] ie by transiently acquiring the protective characteristics of a type 2 Diabetic and/or a type 0 [aka pre-Diabetic] and/or type 4 [aka pregnant Diabetic] wherein that ptGIR helps route fuel to to the brain ... gradually eradicating issues of relative-HYPOglycemia EG as recently experienced by BetterCell. Increased peripheral tissue glucose insulin resistance [ptGIR] provides more reliable brain/nerve glucose 'fuel efficiency' at lower plasma glucose concentrations [PGc].
> 1207 www.tinyurl.com/2k6979 [BetterCell.blogspot.com]
www.DiabetesHealth.com/read/2007/11/02/5548.html
> 1007 tinyurl.com/3aypqg [mristow@mristow.org]
> Somogyi, M, Kirstein, M: Insulin as a cause of extreme hyperglycemia and instability. Week Bull St Louis M Soc 32: 498, 1938.
> 0503 www.tinyurl.com/ys63gk [anson@jhu.edu]

In respect of ALL the opinions included within & associated with this comment ... please AnyOne ... ALSO ask your current Specialist for advice, including the provision of supporting Peer reviewed references, evidencing their understanding of this important matter.
> 1207 www.tinyurl.com/2vp4e9 [DrBernarr@aol.com]

…Warm thanks & AdrenalinLove :)
Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ SAT.29.DEC.2007 @ 23:37hrs (C) "I-Fast-23hours-45minutes-EveryDay-OrMore".

Eating less OFTEN is profoundly more healthy than eating less...

> 0400 www.tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
> 0501 www.tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
> 0503 www.tinyurl.com/ys63gk [anson@jhu.edu]
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
> 1007 tinyurl.com/3aypqg [mristow@mristow.org]
www.DiabetesHealth.com/read/2007/12/19/5575.html
www.DiabetesHealth.com/read/2007/12/03/5558.html
www.DiabetesHealth.com/read/2007/11/29/5564.html
www.DiabetesHealth.com/read/2007/11/27/5541.html
www.DiabetesHealth.com/read/2007/11/02/5548.html
> 0108 www.tinyurl.com/39dbyo [rosenal@peds.ufl.edu]
> 1207 www.tinyurl.com/2k6979 [BetterCell.blogspot.com]
> 1207 www.tinyurl.com/27pwj8 [saskiananette@hotmail.com]
> 1207 www.tinyurl.com/3au3a5 [LoveDiabetes.com]
> 1207 www.tinyurl.com/2v9ajm [LoveDiabetes.com]
> 1107 www.tinyurl.com/2u88dx [mattsonm@grc.nia.nih.gov]
> 1107 www.tinyurl.com/yrr5kd [LoveDiabetes.com]
> 1107 www.tinyurl.com/2gxkqt [Mercola.com]
> 1107 www.tinyurl.com/ytm65u [carolyn_susma@bpost.com]
> 1107 www.tinyurl.com/37fh3g [ConditioningResearch.blogspot.com]
> 1007 www.tinyurl.com/35mnkk [Ian Clark]
Beta-cells continue healthy function even at 30 mmol/l or 540 mg/dL
> 0907 www.tinyurl.com/2vrn55 [pbutler@mednet.ucla.edu]
Douglas Kamerow, US editor of BMJ: Is everything you know wrong?
> 0707 www.tinyurl.com/2x3t6l [dkamerow@bmj.com]
> 0607 www.tinyurl.com/2v2pyx [malcolm@llp.org.uk]
http://www.TheDiabetesBlog.com/2007/04/19/no-food-no-problem
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
www.DiabetesHealth.com/read/2007/04/11/5113.html
http://www.TheDiabetesBlog.com/2007/04/03/the-honeymoon-period
> 0107 www.tinyurl.com/2uj9q7 [Bob@BobRanson.net]
> 0107 www.tinyurl.com/2eyxy3 [john.wahren@ki.se]
> 0107 www.tinyurl.com/2farm9 [temorgan@usc.edu]
> 1206 www.tinyurl.com/y7znor [hmdosch@sickkids.ca]
> 0806 www.tinyurl.com/23x2nv [vbhatia@sgpgi.ac.in]
> 0103 www.tinyurl.com/2rh6fz [hmdosch@sickkids.ca]
> 0802 www.tinyurl.com/2qxuzh [Fortunato.Lombardo@unime.it]
> 0101 www.tinyurl.com/2r293z [nsglaser@ucdavis.edu]
> 0100 www.tinyurl.com/ypozqv [rosenal@peds.ufl.edu]
> 0597 www.tinyurl.com/yr8b95 [Katrina Leskanich]
> 0183 www.tinyurl.com/329umr [hans.lithell@pubcare.uu.se]
> Rosenbloom, AL, Giordano, BP: Chronic over-treatment with insulin in children and adolescents. Am J Dis Child 131: 881-885, 1977.
> 0367 www.tinyurl.com/2uxb99 [Dr Allan Cott]
> Somogyi, M: Exacerbation of diabetes by excess insulin action. Am J Med, 26: 169-191, 1959.
> Somogyi, M, Kirstein, M: Insulin as a cause of extreme hyperglycemia and instability. Week Bull St Louis M Soc 32: 498, 1938.
> www.en.wikipedia.org/wiki/The_Optimal_Diet
> www.en.wikipedia.org/wiki/Coeliac_disease
> www.en.wikipedia.org/wiki/Juice_fasting
> www.en.wikipedia.org/wiki/Inflammation
> www.en.wikipedia.org/wiki/Lyme_disease
> www.en.wikipedia.org/wiki/PH
> www.en.wikipedia.org/wiki/Acidosis
> www.en.wikipedia.org/wiki/Diabulimia
> www.en.wikipedia.org/wiki/Diabetic_ketoacidosis
> www.en.wikipedia.org/wiki/Liver
> www.en.wikipedia.org/wiki/Sarcopenia
> www.en.wikipedia.org/wiki/Growth_hormone
> www.en.wikipedia.org/wiki/Michael_Somogyi
> www.en.wikipedia.org/wiki/Image:Somogyi_rebound.GIF
> www.en.wikipedia.org/wiki/Schizophrenia
> www.en.wikipedia.org/wiki/Parkinson%27s_disease
> www.en.wikipedia.org/wiki/Leukocytosis
> www.HealSelf.org/Alzheimer's%20Disease.html
> www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]

Eating less OFTEN can CURE any diabetes

Posted by bird54 on 30 December 2007

Hi Nick and Anyone Else,
I posted a comment below on the recent article regarding Gary Taubes new book, Good Calories, Bad Calories
http://www.diabeteshealth.com/read/2007/12/27/5606.html

Posted by bird54 on 30 December 2007
Regarding the theory, "eat less, move more..." Read Taubes pp 259-260 "The belief in physical activity as a method of weight control...has long been contradicted by the evidence. When Russel Wilder of the Mayo Clinic lectured on obesity in 1932, be noted that his patients tended to lose more weight with bed rest, 'while usually strenuous physical exercise slows the rate of loss.'"

Posted by bird54 on 30 December 2007
"...we will experience no hunger if we eat nothing at all--zero calories--and our cells are fueled by the protein and fat from our muscle and fat tissue. If we break with our fast with any amount of dietary protein and fat, we'll still feel no hunger. But if we add carbohydrates...we'll be overwhelmed with hunger and will now suffer all the symptoms of food deprivation." Gary Taubes p. 341

Posted by Nicholas Dynes Gracey on 30 December 2007

Eating too OFTEN causes 'relative-HYPOglycemia' & 'inflammation'.

Eating too OFTEN causes & sustains all diabetes.

Pancreatic adaptions to relative-HYPOglycemia down-regulate beta-cells...
> 1002 www.tinyurl.com/36qxn3 [Bill.Hay@UCHSC.edu]
Relieving inflammation CURES diabetes...
> 1206 www.tinyurl.com/y7znor [hmdosch@sickkids.ca]

Posted by bird54 on 16 December 2007
www.DiabetesHealth.com/read/2007/11/29/5564.html

"...I have been ignoring my hunger pangs during the day. I never have glucose in my urine, even after a meal, so what would be the benefit for me to fast, except to cleanse my body, reduce the inflammation, and lose excess body fat?

Dr. Bernarr suggests fasting as a cure to all diseases, not just diabetes. The Bible says, "WHEN you fast", not IF you fast, so it was common practice 2000 years ago for people to fast, whereas nowadays health care practitioners say, "Eat small meals more often, and make sure you eat a nutritious breakfast..."

Dr. Bernarr also suggest strenuous anaerobic exercises to build muscle because glucose in stored in muscle.

I think that Dr. Bernarr's cure for diabetes is very simple and straightforward. However, I think that many people want more scientific basis for a cure..."

Hi bird54, BetterCell, Brent Hoadley & AnyOne else...
Dr Bernarr's CURE for type 1 & type 2 diabetes documents a number of successful cases where love & fresh organic raw foods appear to have contributed to allowing a substantial reduction in psychological & physiological 'inflammation'.

Occasionally eating even a handful ['less' / small in quantity] of potentially irritating foods, nuts, for example, can result in an 'repetitive' inflammatory reaction EG if there is minute quantities of fungus / mold on the nuts or if the Person is sensitive to nuts in other ways [including learned behavioral responses]. AnyOne seriously wanting to CURE diabetes has to be very careful, when they eat, to choose foods that have [or are believed to have] as low potential for inflammation as reasonably possible. Eating one meal a day, within sub15 minutes, allows for '21st century intelligent' meal preparation and daily improvement ... every day better in every way ... in the selection of good wholesome [ultra-low-allergenic] foods that are nutritious & complementary to a SUSTAINABLE healing process [which includes consciously choosing to 'body-build' that food into 'nerves / muscle & bones', every day better in every way, during the 23hrs 45mins, or more, period set aside for focussed more efficient DIGESTION & subsequent assimilation].

Between MAY.2005 [type 1] & JUN.2006 [type 2] Jorgen Vesti Neilsen provided substantial evidence for the benefit of low carbohydrate nutrition. Some 18 to 30 months later ... On FRI.28.DEC.2007 the ADA announced a belief suggesting that there may be benefit in 'low carbohydrate nutrition' but the ADA's 'four types of diabetes' JAN.2007 paper defining type 1 & type 2 diabetes ... has yet to define type 0 as 'pre-diabetes' or acknowledge Dr Suzanne De La Monte's breakthrough research identifying Alzheimer's as a type 3 / type III diabetes [aka brain/nerve glucose insulin resistance / inflammation] ... or announce that the main cause of all 'four types of diabetes' is relative-HYPOglycemia ... because of eating too OFTEN...
> 0505 www.tinyurl.com/329eu3 [jorgen.vesti-nielsen@ltblekinge.se]
> 0606 www.tinyurl.com/3xmzms [jorgen.vesti-nielsen@ltblekinge.se]
> 1207 www.tinyurl.com/29h5ws [http://www.diabetes.org/]
> www.DiabetesHealth.com/read/2007/12/27/5606.html
> 0107 www.tinyurl.com/2maxcf [diabetescare@diabetes.org]
> 1207 www.tinyurl.com/3buzxn [Suzanne_DeLaMonte_MD@Brown.edu]
> 0906 www.tinyurl.com/2sphx5 [Suzanne_DeLaMonte_MD@Brown.edu]
> 0305 www.tinyurl.com/98bf2 [Suzanne_DeLaMonte_MD@Brown.edu]
> 0205 www.tinyurl.com/2e48a7 [Suzanne_DeLaMonte_MD@Brown.edu]

In respect of type 1 & type 2 Dr Bernarr says...

"... CASE HISTORIES OF PATIENTS
WHOM WE HELPED HEAL OF DIABETES 1

Joan B., age 29, in 1985, had Type 1, Juvenile Diabetes, for 17 years. She took insulin daily. She was always thin, no matter how she ate, had increased urination, blurred vision, vaginal itching, nocturnal enuresis, was very thirsty and weak. After she was under our care, she never took insulin again, her vision became normal, never had vaginal itching, never had increased urination nor nocturnal enuresis again, exercised daily with intensity, gained muscular bodyweight and looked beautiful. We have successfully helped heal many cases of Diabetes 1, i.e., Insulin Dependent Diabetes. To our knowledge, we are the only health practitioners in the world, to have helped heal Diabetes 1. There are no other health or spiritual practitioners in the world who have ever written or lectured about their having helped heal Diabetes 1. A description of one of our Diabetes 1 cases that we helped heal, was described in David Wolfe's "Sunfood Lifestyle" first edition. David Wolfe met her and knew her before and after her Juvenile Diabetes. Her case was also described on David Karas Internet, Raw-Food@Maelstrom.StJohn.Edu message board. David Karas met her and knew her before and after her Juvenile Diabetes. She was 25 years old. She had Juvenile Diabetes for 10 years. She attended our monthly raw food potlucks-lectures-discussions, before and after her being insulin free.

"... CASE HISTORIES OF PATIENTS
WHOM WE HELPED HEAL OF DIABETES 2

Michael S., age 67, in 1963, had Type 2, adult onset diabetes for 21 years. He took insulin daily. He was 100 pounds overweight, had blurred vision, had peripheral neuropathy, was always fatigued and generally thirsty. After he was under our care, he never took insulin again, lost the fat in his body, developed muscular tone throughout his body, exercised intensely daily, developed normal vision, his peripheral neuropathy and constant thirst disappeared..."

DIETARY DIABETES PROTOCOL = DPP

In the absence of any evidence to the contrary it appears that Dr Bernarr's dietary diabetes protocol [DDP] of 'body-building' upon fresh organic raw foods also helps to 'body-build healthy pancreatic tissue' even, for example, in an underweight type 1 who had been taking insulin for some 17 years...
> www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]
CPR or coma + water + time ?
> tinyurl.com/2dpdgo [DrBernarr@aol.com]

K-WAS-NIEW-SKI's DPP

For some 30 years Dr Jan Kwasniewski has been successfully treating type 1 Diabetics, without insulin, with a DPP called the "Optimal Diet".

In Poland there are approximately 30 health clinics and 300 doctors that practice according to the teachings of Kwasniewski's Optimal Diet ...
'...Type 1 diabetes can almost always be cured. You must reduce the quantity of carbohydrates consumed to 50±15 grams per day. Because 100 grams of protein can produce about 56 grams of carbohydrates. Therefore, it is necessary to consume protein of the highest biological value which is contained in egg yolks, livers and kidneys. Minimum of a half gram of protein per kilogram of body weight per day will be sufficient. When glucose falls to a level of 6.7 - 7.2 mmol/l, and the doses of insulin are small, insulin should be given up for good. Diabetes will certainly not return providing you stick to the optimal diet Theoretically, reducing the amount of carbohydrates consumed to the recommended level should cure the diabetic on the first day. But in practice is not so simple. The diabetes is curable only after several weeks, and sometimes longer...'
> www.tinyurl.com/2k46q3 [spopis@iafrica.com]
> www.en.wikipedia.org/wiki/The_Optimal_Diet
> www.tinyurl.com/yobcdw [gp@wgp.com.pl]
> 0207 www.tinyurl.com/34gb7k [ewestman@duke.edu]
> 0307 www.tinyurl.com/2rjuxf [alessandra_freitas@msn.com]

WHAT IS YOUR DDP ?

HOW HAS YOUR DDP BEEN SELECTED TO HELP HEAL & 'BODY-BUILD' YOUR BETA-CELLS?

WHY CHOOSE A DPP TO MINIMIZE INFLAMMATION WHEN SOME LOW CARB DIETS CAUSE WEIGHT LOSS BY INFLAMMATION?

Eating less OFTEN and digesting more OFTEN can de-congest the liver, can reduce inflammation, can reduce auto-immune disease, can reduce brain/nerve glucose insulin resistance [bnGIR], can increase peripheral tissue glucose insulin resistance [ptGIR] and can CURE diabetes...
> 0307 www.tinyurl.com/3cv9t9 [jim@jbjmd.com]
> www.en.wikipedia.org/wiki/Liver

The main avoidable CAUSE of diabetes and way to CURE diabetes is set out in the comments & associated links above and in a more concentrated format as follows...

Eating less OFTEN cures type 2 diabetes and eating less OFTEN, even more OFTEN, cures type 1 diabetes.

Lithell's 1983 chronic inflammation reference relates to 'fasting' BUT that type of fasting / aka digestion is without any mention of the word "OFTEN" and therefore lacks the SUSTAINABILITY of 'better digestion associated benefits' of eating less OFTEN aka intermittent eating / intermittent fasting...
> 0183 www.tinyurl.com/329umr [hans.lithell@pubcare.uu.se]

INTERMITTENT-EATING

The difference between eating / fasting vs intermittent eating & intermittent fasting is that the results of an intermittent system are sustainable. EG sustainable to achieve relief from inflammation and/or sustainable to the stage of a complete CURE. It's a matter of time & effort ... like training to be a champion gymnast or intermittent-exercising ... every day better in every way ... in order to make SUSTAINABLE progress.

Diseases associated with inflammation such as 'Coeliac / Celiac' and/or 'Severe Type 1a Diabetes' and/or 'Lymes' need an intermittent eating & intermittent exercising system that ... every day better in every way ... efficiently reduces excess inflammation and efficiently builds increased muscle mass. A fast way [in my opinion] to achieve that is ... one meal a day [or less] of EXCLUSIVELY "fresh organic raw liquidiet nutrition" of minimally allergenic juicy water-rich foods [EG fruits / vegetables / raw egg yolks]. Modern technology makes this possible & sustainable. Vast quantities can be enjoyably 'eaten' within 15 minutes ... followed 23 HOURS 45 MINUTES - OR MORE of thinking, planning, exercising, digestion & assimilation BEFORE eating again. Consuming 'solid food' and/or potentially 'allergenic food' in the presence of severe inflammatory disease, within the delicate 'digestive' tissue linings and/or the pancreas, is out-of-order if there is a healthier alternative...
> www.en.wikipedia.org/wiki/Coeliac_disease
> www.en.wikipedia.org/wiki/Celiac_lymph_nodes
> 1206 www.tinyurl.com/y7znor [hmdosch@sickkids.ca]
> www.en.wikipedia.org/wiki/Juice_fasting
> www.en.wikipedia.org/wiki/Inflammation
> www.en.wikipedia.org/wiki/Lyme_disease

To properly digest & assimilate 1 meal a day various hormones need to be stimulated in the body that will encourage nerve & muscle growth and create an 'assimilation-hunger' within body tissues. Eating without assimilation due to inflammation is beyond futile...
> www.en.wikipedia.org/wiki/Sarcopenia

In my opinion the world leader in EFFICIENTLY building maximum muscle mass, whilst eating the MINIMUM amount of [inflammation producing] food, is Pete Sisco...
> http://www.getthisstrong.com/ [support@superrepequipment.com]
> www.HealSelf.org/Strong-Become%20Stronger.html [Dr Bernarr]
> http://www.matthewfurey.com/ [zen]
> http://www.mattfurey.com/ [conditioning]

Sustainable weight control is about understanding HOW to shed fat and/or build muscle. EveryOne should understand what Pete Sisco, Dr Bernarr & Matt Furey are teaching about becoming stronger.

INTERMITTENT-EXERCISING
FOR 5 SECONDS OR MORE EVERY DAY...

AnyOne who can do a wall-facing-handstand [toes supported by the wall] for more than 5 seconds can both substantially & sustainably increase muscle mass, every day better in every way, by increasing their record hold-time for holding that 'isometric gymnastic posture' by 5 seconds extra EVERY day.

Please feedback your comments on your personal current record for the abovementioned 'posture-hold-time' and record it daily on a wall somewhere and watch the daily improvement. [EveryOne serious about healing a disease should also measure their pH at least once daily].

Anecdotally a number of TV documentaries feature tribes etc who sustain Themselves with the benefit of 1 meal a day [or less]. The muscle tone and anatomy of the Men, Women & Children is usually extra-ordinarily healthy.
> www.en.wikipedia.org/wiki/Sarcopenia

ALTERNATIVES & CHOICES

Certain diets/mediations owe their 'weight-loss' associations to increased inflammation. EveryOne should learn from Pete Sisco as to actually how little food is needed to become stronger [EG when growth hormone is sustainably stimulated] and to be courageous enough to secure the support of a licensed medical Practitioner who is actually fit & strong & clearly manifests an understanding of the benefits of ... fresh organic raw liquidiet nutrition ... to digestion, to assimilation & to 'body-building' [including beta-cells]; AND please discuss the following intermittent eating / fasting protocol as suitable for both fat reduction [low carb] and muscle & fat gain [high carb] ... reading between the lines in so far as being applicable to AnyOne else who is diabetes/medication free? Details of any Practitioner's feedback / alternative DPP or strategy for inflammation-free 'body-building' would be most appreciated...
> www.en.wikipedia.org/wiki/Growth_hormone

WATer CURES DIABETES & INFLAMMATION

(A) Maintain maximum comfortable hydration [drinking / naso-gastic] and minimum [50-75% reduction] basal insulin [eg type 1 exogenous / type 2 endogenous] to prevent ketoacidosis [pH > 7.1] ie the hourly target is pH control in the range 7.2 - 7.5 and plasma blood glucose concentration STRICTLY above 150 mg/dL (9 mmol/L) and below approximately 350 mg/dL (19 mmol/L) which should encourage Diabetic glucose urination of excess plasma glucose concentrations and simultaneously minimize/prevent any possibility of relative-HYPOglycemia [the apparent CAUSE of 'compensatory-HYPERglycemia' / aka diabetes].
> 0108 www.tinyurl.com/39dbyo [rosenal@peds.ufl.edu]
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
> 0100 www.tinyurl.com/ypozqv [rosenal@peds.ufl.edu]
Cerebral cGc is approx 40mg/dL less than Plasma pGc concentration
> 1203 www.tinyurl.com/39zu9o [Lori A Markham]
> www.en.wikipedia.org/wiki/The_Optimal_Diet
> www.en.wikipedia.org/wiki/PH
> www.en.wikipedia.org/wiki/Acidosis
> www.en.wikipedia.org/wiki/Diabulimia
> www.en.wikipedia.org/wiki/Diabetic_ketoacidosis

1 x SUB15 MEAL EVERY DAY for TSG

(B) Eat not less but less OFTEN … specifically one meal a day [or less] but always within sub15 minutes ... one meal fully expected to create the healing benefits of transient supernormal glycemia [TSG] … Eat JUST clean water [zero% carbohydrate] between meals [selected to maintain pH above 7.1 and minimize any allergenic response] & eat ONLY when your blood plasma glucose concentration [pGc] level, following your previous 'nutritionally focussed' eat, has naturally reduced to your chosen baseline plasma glucose range [EG 150 mg/dL (9 mmol/L) to 350 mg/dL (19 mmol/L) and as related to the relative fuel demands of your particular daily activity level] and consciously helping your body learn this habit, of 'supply & demand' glucose control, makes your cure sustainable c/o daily optimizing / TSG fittening increased adaptive 'peripheral tissue glucose insulin resistance' [ptGIR] to help route glucose fuel supply to the brain/nerves ... again simultaneously minimizing/preventing any possibility of relative-HYPOglycemia [the apparent CAUSE of 'compensatory-HYPERglycemia' / aka diabetes] and thereby facilitating beta-cell 'body-building'...
> 1107 www.tinyurl.com/2u88dx [mattsonm@grc.nia.nih.gov]
Beta-cells can be healthy even at 30 mmol/l or 540 mg/dL [pH > 7.1]
> 0907 www.tinyurl.com/2vrn55 [pbutler@mednet.ucla.edu]
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
> 0503 www.tinyurl.com/ys63gk [anson@jhu.edu]
> 0501 www.tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]

TYPE 1 BECOMES healthy TYPE 2 BECOMES healthy TYPE 0

(C) Await daily recovery [to relatively lower plasma glucose concentrations], every day better in every way, SUSTAINABLE, in respect of your increased reduction of relative-HYPOglycemia IE increasingly efficient reduction of the CAUSE [of 'compensatory-HYPERglycemia'] … increasingly efficiently facilitates the gradual recovery your beta-cells & increased brain/nerve insulin sensitivity … ie gradually towards the total sustainable cure [days/weeks/months for type 1a & type 1.5 … or … hours/days/weeks for type 1b & type 2]. Type 1 CURE by TSG increasing peripheral tissue glucose insulin resistance [ptGIR] ... IE by transiently acquiring the protective characteristics of a type 2 Diabetic and/or a type 0 [aka pre-Diabetic] and/or type 4 [aka pregnant Diabetic] wherein that ptGIR helps route fuel to to the brain ... gradually eradicating issues of relative-HYPOglycemia EG as recently experienced by BetterCell. Increased peripheral tissue glucose insulin resistance [ptGIR] provides more reliable brain/nerve glucose 'fuel efficiency' at lower plasma glucose concentrations [PGc].
> 1207 www.tinyurl.com/2k6979 [BetterCell.blogspot.com]
www.DiabetesHealth.com/read/2007/11/02/5548.html
> 1007 tinyurl.com/3aypqg [mristow@mristow.org]
> Somogyi, M, Kirstein, M: Insulin as a cause of extreme hyperglycemia and instability. Week Bull St Louis M Soc 32: 498, 1938.
> 0503 www.tinyurl.com/ys63gk [anson@jhu.edu]

In respect of ALL the opinions included within & associated with this comment ... please AnyOne ... ALSO ask your current Specialist for advice, including the provision of supporting Peer reviewed references, evidencing their understanding of this important matter.
> 1207 www.tinyurl.com/2vp4e9 [DrBernarr@aol.com]

…Warm thanks & AdrenalinLove :)
Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ SUN.30.DEC.2007 @ 23:05hrs (C) "I-Fast-23hours-45minutes-EveryDay-OrMore".

> Eating too OFTEN causes & sustains all diabetes...

> Diabetes is not a disease ... diabetes is the CURE for relative-HYPOglycemia...

> Eating less OFTEN is profoundly more healthy than eating less...

> 0400 www.tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
> 0501 www.tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
> 0503 www.tinyurl.com/ys63gk [anson@jhu.edu]
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
> 1007 tinyurl.com/3aypqg [mristow@mristow.org]
www.DiabetesHealth.com/read/2007/12/27/5606.html
www.DiabetesHealth.com/read/2007/12/19/5575.html
www.DiabetesHealth.com/read/2007/12/03/5558.html
www.DiabetesHealth.com/read/2007/11/29/5564.html
www.DiabetesHealth.com/read/2007/11/27/5541.html
www.DiabetesHealth.com/read/2007/11/02/5548.html
> 0108 www.tinyurl.com/39dbyo [rosenal@peds.ufl.edu]
> 1207 www.tinyurl.com/2k6979 [BetterCell.blogspot.com]
> 1207 www.tinyurl.com/27pwj8 [saskiananette@hotmail.com]
> 1207 www.tinyurl.com/3au3a5 [LoveDiabetes.com]
> 1207 www.tinyurl.com/3buzxn [Suzanne_DeLaMonte_MD@Brown.edu]
> 1207 www.tinyurl.com/2v9ajm [LoveDiabetes.com]
> 1107 www.tinyurl.com/2u88dx [mattsonm@grc.nia.nih.gov]
> 1107 www.tinyurl.com/yrr5kd [LoveDiabetes.com]
> 1107 www.tinyurl.com/2gxkqt [Mercola.com]
> 1107 www.tinyurl.com/ytm65u [carolyn_susma@bpost.com]
> 1107 www.tinyurl.com/37fh3g [ConditioningResearch.blogspot.com]
> 1007 www.tinyurl.com/35mnkk [Ian Clark]
Beta-cells continue healthy function even at 30 mmol/l or 540 mg/dL [pH > 7.1]...
> 0907 www.tinyurl.com/2vrn55 [pbutler@mednet.ucla.edu]
Douglas Kamerow, US editor of BMJ: Is everything you know wrong?...
> 0707 www.tinyurl.com/2x3t6l [dkamerow@bmj.com]
> 0607 www.tinyurl.com/2v2pyx [malcolm@llp.org.uk]
http://www.TheDiabetesBlog.com/2007/04/19/no-food-no-problem
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
www.DiabetesHealth.com/read/2007/04/11/5113.html
http://www.TheDiabetesBlog.com/2007/04/03/the-honeymoon-period
> 0207 www.tinyurl.com/34gb7k [ewestman@duke.edu]
> 0207 www.tinyurl.com/34gb7k [ewestman@duke.edu]
> 0107 www.tinyurl.com/2uj9q7 [Bob@BobRanson.net]
> 0107 www.tinyurl.com/2eyxy3 [john.wahren@ki.se]
Type 4, 3, 2, 1, 0 diabetes ... the ADA definitions...
> 0107 www.tinyurl.com/2maxcf [diabetescare@diabetes.org]
> 0107 www.tinyurl.com/2farm9 [temorgan@usc.edu]
Relieving inflammation cures diabetes...
> 1206 www.tinyurl.com/y7znor [hmdosch@sickkids.ca]
> 0906 www.tinyurl.com/2sphx5 [Suzanne_DeLaMonte_MD@Brown.edu]
> 0806 www.tinyurl.com/23x2nv [vbhatia@sgpgi.ac.in]
> 0305 www.tinyurl.com/98bf2 [Suzanne_DeLaMonte_MD@Brown.edu]
> 0205 www.tinyurl.com/2e48a7 [Suzanne_DeLaMonte_MD@Brown.edu]
> 0103 www.tinyurl.com/2rh6fz [hmdosch@sickkids.ca]
Pancreatic adaptions to relative hypoglycaemia down-regulate beta-cells...
> 1002 www.tinyurl.com/36qxn3 [Bill.Hay@UCHSC.edu]
> 0802 www.tinyurl.com/2qxuzh [Fortunato.Lombardo@unime.it]
> 0101 www.tinyurl.com/2r293z [nsglaser@ucdavis.edu]
> 0100 www.tinyurl.com/ypozqv [rosenal@peds.ufl.edu]
> 0597 www.tinyurl.com/yr8b95 [Katrina Leskanich]
> 0183 www.tinyurl.com/329umr [hans.lithell@pubcare.uu.se]
> Rosenbloom, AL, Giordano, BP: Chronic over-treatment with insulin in children and adolescents. Am J Dis Child 131: 881-885, 1977.
> 0367 www.tinyurl.com/2uxb99 [Dr Allan Cott]
> Somogyi, M: Exacerbation of diabetes by excess insulin action. Am J Med, 26: 169-191, 1959.
> Somogyi, M, Kirstein, M: Insulin as a cause of extreme hyperglycemia and instability. Week Bull St Louis M Soc 32: 498, 1938.
> www.en.wikipedia.org/wiki/The_Optimal_Diet
> www.en.wikipedia.org/wiki/Coeliac_disease
> www.en.wikipedia.org/wiki/Juice_fasting
> www.en.wikipedia.org/wiki/Inflammation
> www.en.wikipedia.org/wiki/Lyme_disease
> www.en.wikipedia.org/wiki/PH
> www.en.wikipedia.org/wiki/Acidosis
> www.en.wikipedia.org/wiki/Diabulimia
> www.en.wikipedia.org/wiki/Diabetic_ketoacidosis
> www.en.wikipedia.org/wiki/Liver
> www.en.wikipedia.org/wiki/Sarcopenia
> www.en.wikipedia.org/wiki/Growth_hormone
> www.en.wikipedia.org/wiki/Michael_Somogyi
> www.en.wikipedia.org/wiki/Image:Somogyi_rebound.GIF
> www.en.wikipedia.org/wiki/Schizophrenia
> www.en.wikipedia.org/wiki/Parkinson%27s_disease
> www.en.wikipedia.org/wiki/Leukocytosis
> www.HealSelf.org/Alzheimer's%20Disease.html
> www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]

Eating less OFTEN can CURE any diabetes

Posted by bird54 on 31 December 2007

Hi Nick,
You stated, "For some 30 years Dr Jan Kwasniewski has been successfully treating type 1 Diabetics, without insulin, with a DPP (diabetes dietary protocol) called the "Optimal Diet". '...Type 1 diabetes can almost always be cured. You must reduce the quantity of carbohydrates consumed to 50±15 grams per day. Because 100 grams of protein can produce about 56 grams of carbohydrates. Therefore, it is necessary to consume protein of the highest biological value which is contained in egg yolks, livers and kidneys."
Then you said, "WHY CHOOSE A DPP TO MINIMIZE INFLAMMATION WHEN SOME LOW CARB DIETS CAUSE WEIGHT LOSS BY INFLAMMATION?"
Can you explain what you mean by your last statement, "...some low carb diets cause weight loss by inflammation."?
I thought low carb diets "reduced" inflammation. Low carb diets reduce insulin production/requierements diabetics. Fasting also reduces insulin levels.
I totally agree with you on intermittent fasting, but I am confused about your statement on inflammation and low carb diets.
By the way, you absolutely have to write a book. I just read Good Calories Bad Calories by Gary Taubes. He is a journalist, not a scientist, and all he does is quote other people--so none of his ideas are his own--yet his book is fantastic!

Posted by bird54 on 31 December 2007

Hi Nick,
I'm going to try to summarize your theory of the cause and cure of diabetes. Let me know if this is correct:
Diabetes is caused by relative hypoglycemia. Relative hypoglycemia is caused by eating often, especially meals high in carbohydrates. When one eats, the blood stream is flooded with glucose. The pancreas releases insulin. Insulin transports the glucose into tissues and/or fat cells. As a result, blood sugar drops, resulting in relative hypoglycemia. Relative hypoglycemia causes the brain and nerve cells to be deprived of glucose. The body compensates by becoming insulin resistant, thereby not allowing the glucose to enter the tissues, but instead to remain in the blood stream to supply the brain and nerves. The more one eats, the higher ones blood sugar rises in order to prevent hypoglycemia. Therefore the cure to diabetes is to eat less often so that there are fewer fluctuations in blood sugar and therefore fewer episodes of relative hypoglycemia.
Eating also causes inflammation (due to glucose intolerance and/or food intolerances) When the pancreatic beta cells become inflamed, they stop producing insulin, as a protective mechanism because insulin is what causes hypoglycemia. So diabetes is a vicious cycle that can only be broken by intermittent fasting.
Is this correct?

Posted by Nicholas Dynes Gracey on 31 December 2007

Before 2008 ... the CURE for all 'diabetes' was here all the time We ALL just need to work togetHER to help US realize ...
> 0597 www.tinyurl.com/yr8b95 [Katrina Leskanich]

Please read this present post together with my post @ http://www.diabeteshealth.com/ @ SUN.30.DEC.2007 @ 23:05hrs...
http://www.diabeteshealth.com/read/2007/11/29/5564.html#comments

Research by Saskia N van der Crabben on 04 December 2007
...Intermittent-fasting sustainably stimulates substantially increased beneficial 'peripheral tissue glucose insulin resistance' ptGIR to help preferentially glucose-fuel the brain/nerves and defend brain/nerves from relative-HYPOglycemia...
> 1207 www.tinyurl.com/27pwj8 [saskiananette@hotmail.com]

Research by Debra A Fadool on 04 April 2000
...Intermittent-fasting sustainably stimulates substantially increased beneficial 'brain/nerve glucose insulin production' to help preferentially glucose-fuel the brain/nerves and defend brain/nerves from relative-HYPOglycemia...
> 0400 www.tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]

Posted by bird54 on 30 December 2007
"...we will experience no hunger if we eat nothing at all--zero calories--and our cells are fueled by the protein and fat from our muscle and fat tissue. If we break with our fast with any amount of dietary protein and fat, we'll still feel no hunger. But if we add carbohydrates...we'll be overwhelmed with hunger and will now suffer all the symptoms of food deprivation." Gary Taubes p. 341
> www.DiabetesHealth.com/read/2007/11/29/5564.html

Research by Gary Taubes on 25 September 2007
"...we will experience no hunger if we eat nothing at all--zero calories--and our cells are fueled by the protein and fat from our muscle and fat tissue. If we break with our fast with any amount of dietary protein and fat, we'll still feel no hunger. But if we add carbohydrates, as Drenick noted, we'll be overwhelmed with hunger and will now suffer all the symptoms of food deprivation. So why is it when we add carbohydrates to the diet we get hungry, if not irritable, lathargic and depressed, but this will not happen when we add only protein and fat? How can the amount of calories possibly be the critical factor?"
> 1007 www.tinyurl.com/25dp5b [Andrew Weil]
> 0907 www.tinyurl.com/39vfdm [Gary Taubes]
> 0607 www.tinyurl.com/2v2pyx [Malcolm Kendrick]
> 0293 www.tinyurl.com/268oz3 [Ernst J. Drenick (HOW ?)]

Hi bird54, Anthony Colpo, Saskia N van der Crabben, Shane Ellison, Debra A Fadool, Lee Iacocca, Joel Kauffman, Malcolm Kendrick, Scott King, Suzanne De La Monte, Byron Richards, Lynne McTaggert, Gary North, Uffe Ravnskov, Gary Taubes & Andrew Weil...

"Eating too OFTEN" ... substantially more than is truly NEEDED ... for ANY particular Person ... at a particular TIME of their life ... causes relative-HYPOglycemia resulting in actual brain/nerve starvation and potential associated GENUINE hunger because "Eating too OFTEN" [in those particular circumstances]:-

(A) Sustainably stimulates substantially reduced 'peripheral tissue glucose insulin resistance' ptGIR ... resulting in glucose flooding away from the brain/nerves and into the fat / liver / muscles ... resulting in actual brain/nerve starvation and genuine hunger ... increasing appetite for eating and potential obesity; and

(B) Sustainably stimulates substantially reduced 'brain/nerve glucose insulin production' ... resulting in actual brain/nerve starvation and genuine hunger ... increasing appetite for eating and potential obesity; and

...the less the ptGIR the more the likelihood of hunger/appetite, the more the genuine NEED to self-medicate with high carbohydrate carbophilia and the greater the potential obesity until saved by love / diabetes...
> 0367 www.tinyurl.com/2uxb99 [Dr Allan Cott]
> www.en.wikipedia.org/wiki/Schizophrenia
Pancreatic adaptions to relative-HYPOglycaemia down-regulate beta-cells...
> 1002 www.tinyurl.com/36qxn3 [Bill.Hay@UCHSC.edu]
Relative-HYPOglycemia is the CAUSE of 'compensatory-HYPERglycemia' / aka diabetes [which EG helps prevent Alzheimer's, Parkinsons & Schizophrenia]...
> 0198 www.tinyurl.com/yr27rt [okh@hst.aau.dk]
> www.en.wikipedia.org/wiki/Parkinson%27s_disease
> www.en.wikipedia.org/wiki/Leukocytosis
> www.en.wikipedia.org/wiki/Alzheimer's_disease
> www.HealSelf.org/Alzheimer's%20Disease.html

In respect of ALL the opinions included within & associated with this comment ... please AnyOne ... ALSO ask your current Specialist for advice, including the provision of supporting Peer reviewed references, evidencing their understanding of this important matter.
> 1207 www.tinyurl.com/2vp4e9 [DrBernarr@aol.com]

…Warm thanks, Happy new years & AdrenalinLove :)
Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ MON.31.DEC.2007 @ 17:23hrs (C) "I-Fast-23hours-45minutes-EveryDay-OrMore"

Eating too OFTEN causes & sustains all diabetes...

> Diabetes is not a disease ... diabetes is the CURE for relative-HYPOglycemia...

Eating less OFTEN is profoundly more healthy than eating less...

> 0108 www.tinyurl.com/39dbyo [rosenal@peds.ufl.edu]
> 1207 www.tinyurl.com/27pwj8 [saskiananette@hotmail.com]
> 1107 www.tinyurl.com/2u88dx [mattsonm@grc.nia.nih.gov]
> 1007 www.tinyurl.com/3aypqg [mristow@mristow.org]
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
> 1206 www.tinyurl.com/y7znor [hmdosch@sickkids.ca]
> 0205 www.tinyurl.com/2e48a7 [Suzanne_DeLaMonte_MD@Brown.edu]
> 0503 www.tinyurl.com/ys63gk [anson@jhu.edu]
> 0501 www.tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
> 0400 www.tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
www.DiabetesHealth.com/read/2007/12/27/5606.html
www.DiabetesHealth.com/read/2007/12/19/5575.html
www.DiabetesHealth.com/read/2007/12/03/5558.html
http://www.DiabetesHealth.com/read/2007/11/29/5564.html
www.DiabetesHealth.com/read/2007/11/27/5541.html
www.DiabetesHealth.com/read/2007/11/02/5548.html
www.DiabetesHealth.com/read/2007/04/11/5113.html
Douglas Kamerow, US editor of BMJ: Is everything you know wrong?...
> 0707 www.tinyurl.com/2x3t6l [dkamerow@bmj.com]
www.TheDiabetesBlog.com/2007/04/19/no-food-no-problem
www.TheDiabetesBlog.com/2007/04/03/the-honeymoon-period
www.tinyurl.com/3au3a5 [LoveDiabetes.com]
www.tinyurl.com/2v9ajm [http://www.lovediabetes.com/]
www.tinyurl.com/yrr5kd [LoveDiabetes.com]
> www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]

Eating less OFTEN can CURE any diabetes

Posted by bird54 on 31 December 2007

Happy New Year!
Add this to your list of links
http://www.apinchofhealth.com/resources/lowcarb/stefansson-adventures-in-diet-part-two.html
Vilhjalmur Stefansson's experiment of eating only meat for over a year in perfect health and his story of surviving for 5 years on meat only while living with the Inuits.

Posted by Nicholas Dynes Gracey on 1 January 2008

Posted by bird54 on 31 December 2007
http://www.diabeteshealth.com/read/2007/11/29/5564.html#comments

Hi Nick,
I'm going to try to summarize your theory of the cause and cure of diabetes. Let me know if this is correct:
Diabetes is caused by relative hypoglycemia. Relative hypoglycemia is caused by eating often, especially meals high in carbohydrates. When one eats, the blood stream is flooded with glucose. The pancreas releases insulin. Insulin transports the glucose into tissues and/or fat cells. As a result, blood sugar drops, resulting in relative hypoglycemia. Relative hypoglycemia causes the brain and nerve cells to be deprived of glucose. The body compensates by becoming insulin resistant, thereby not allowing the glucose to enter the tissues, but instead to remain in the blood stream to supply the brain and nerves. The more one eats, the higher ones blood sugar rises in order to prevent hypoglycemia. Therefore the cure to diabetes is to eat less often so that there are fewer fluctuations in blood sugar and therefore fewer episodes of relative hypoglycemia. Eating also causes inflammation (due to glucose intolerance and/or food intolerances) When the pancreatic beta cells become inflamed, they stop producing insulin, as a protective mechanism because insulin is what causes hypoglycemia. So diabetes is a vicious cycle that can only be broken by intermittent fasting.
Is this correct?

Hi bird54 [yes pretty much],

Happy New Years to You & AnyOne else...

Another theory, proposed in 1978, as to the CAUSE and CURE of diabetes ... apparently cured 7 out of 32 'type 1 Diabetics' & cured 31 out of 87 'type 2 Diabetics'. However well that CURE works for CURING type 1 & type 2 diabetes there is still room for improvement and alternative theories.
> 0181 www.tinyurl.com/gyhr9 [Dr.Schnitzer@t-online.de]

Here's an edit to 'bird54's version' of the proposed theory of the CAUSE and CURE of diabetes as per the comments of 30&31.DEC.2007...

... [Should be updated frequently with increasing understanding and AnyOne else's suggestions for updating and/or amending re their belief as to the CAUSE and CURE of diabetes ... would be most appreciated] ...

Diabetes is caused by eating too OFTEN which reduces brain/nerve insulin production, reduces liver 'digestion efficiency' and reduces 'glucose insulin resistance' [GIR] ... increasing glucose entry into [and storage in] any 'peripheral tissues' [having insulin receptors] such as liver, fat & muscle cells. Relative-HYPOglycemia is caused by eating too OFTEN especially meals relatively high in carbohydrates. When AnyOne eats, especially carbohydrates/glucose, the blood-stream is usually flooded with glucose. The pancreas releases insulin in response to increasing concentrations of glucose. Insulin increases the efficiency of glucose entry into [and storage in] 'peripheral tissues' such as liver, fat & muscle cells. As a result, blood glucose concentration drops, sometimes resulting in relative-HYPOglycemia. Relative-HYPOglycemia results from brain & nerve cells being deprived of the glucose that has been 'drained' out of the blood-stream by the insulin. The body compensates, by becoming 'glucose insulin resistant', thereby resisting glucose entry into any peripheral tissues having insulin receptors. Now there is a higher glucose concentration remaining in the blood-stream to help better supply the glucose-fuel needs of the brain & nerves. That process is called 'compensatory-HYPERglycemia'. Now whenever AnyOne [who's body is trying to prevent relative-HYPOglycemia] eats EG 'excess glucose' ... their blood glucose concentration rises temporarily, to an above-the-national-average concentration [transient supernormal glycemia aka TSG] in order to help prevent relative-HYPOglycemia [EG type 0, type1, type 2 & type 4 diabetes]. Eating less OFTEN increases glucose insulin resistance and increases 'localized' brain/nerve insulin production [all for 'fine-tuning' of brain/nerve glucose metabolism]. Therefore the CURE for diabetes is to eat less OFTEN so that there are fewer rapid-reductions in brain/nerve glucose concentration and therefore fewer episodes of relative-HYPOglycemia. When EG a Child is growing ... above-the-national-average concentrations of growth hormone are sometimes produced which cause relative-HYPOglycemia. When such a Child eats too OFTEN the pancreatic beta-cells become 'inflamed' in order to help reduce insulin production and increase 'compensatory-HYPERglycemia' [EG type 1a diabetes] ... all in order to help protect the brain/nerves from potential SEVERE acute relative-HYPOglycemia. When an aging Adult eats too OFTEN too often IE too OFTEN for too-LONG-a-time ... the brain/nerve cells become chronically 'starved & inflamed' from lack of 'localized' brain/nerve insulin production, and increase 'compensatory loss-of-appetite' / 'loss-of-memory-to-eat' / 'eating less OFTEN' [EG type 3a diabetes], to help protect the brain from potential SEVERE chronic relative-HYPOglycemia [by increasing 'localized' brain/nerve insulin production]. Eating also causes inflammation [due to various food intolerances associated with an inefficient liver function]. Diabetes is a protective cycle that can be controlled and/or CURED, as required, by intermittent-fasting [which also increases liver 'digestion efficiency'] and intermittent-eating of minimally allergenic foods.
How reasonable is this "Gracey HYPOthesis"?

In respect of ALL the opinions included within & associated with this comment ... please AnyOne ... ALSO ask your current licensed Specialist for advice, including the provision of supporting Peer reviewed references, evidencing their understanding of this important matter.
> 0367 www.tinyurl.com/2uxb99 [Dr Allan Cott]
> www.HealSelf.org/Diabetes.html [DrBernarr@aol.com]

…Warm thanks & AdrenalinLove :)
Nick Gracey, BSc(Hons) Medical Biochemistry, Birmingham University, UK, WATerian c/o http://www.diabeteshealth.com/ @ TUE.01.JAN.2008 @ 21:21hrs (C) "I-Fast-23hours-45minutes-EveryDay-OrMore"

Eating too OFTEN causes & sustains all diabetes...

> Diabetes is not a disease ... diabetes is the CURE for relative-HYPOglycemia...

Eating less OFTEN is profoundly more healthy than eating less...

> 0108 www.tinyurl.com/39dbyo [rosenal@peds.ufl.edu]
> 1207 www.tinyurl.com/27pwj8 [saskiananette@hotmail.com]
> 1107 www.tinyurl.com/2u88dx [mattsonm@grc.nia.nih.gov]
> 1007 www.tinyurl.com/3aypqg [mristow@mristow.org]
> 0407 www.tinyurl.com/29kvda [zangend@hadassah.org.il]
> 1206 www.tinyurl.com/y7znor [hmdosch@sickkids.ca]
> 0205 www.tinyurl.com/2e48a7 [Suzanne_DeLaMonte_MD@Brown.edu]
> 0503 www.tinyurl.com/ys63gk [anson@jhu.edu]
> 0501 www.tinyurl.com/yqf8gj [maeda@ys7.u-shizuoka-ken.ac.jp]
> 0400 www.tinyurl.com/2j7p3t [dfadool@neuro.fsu.edu]
> 0100 www.tinyurl.com/ypozqv [rosenal@peds.ufl.edu]
www.DiabetesHealth.com/read/2007/12/27/5606.html
www.DiabetesHealth.com/read/2007/12/19/5575.html
www.DiabetesHealth.com/read/2007/12/03/5558.html
http://www.DiabetesHealth.com/read/2007/11/29/5564.html
www.DiabetesHealth.com/read/2007/11/27/5541.html
www.DiabetesHealth.com/read/2007/11/02/5548.html
www.DiabetesHealth.com/read/2007/04/11/5113.html
Douglas Kamerow, US editor of BMJ: Is everything you know wrong?...
> 0707 www.tinyurl.com/2x3t6l [dkamerow@bmj.com]
www.TheDiabetesBlog.com/2007/04/19/no-food-no-problem
www.TheDiabetesBlog.com/2007/04/03/the-honeymoon-period
> 0198 www.tinyurl.com/yr27rt [okh@hst.aau.dk]
> 0367 www.tinyurl.com/2uxb99 [Dr Allan Cott]
> 1135 www.tinyurl.com/2v8pyq [feedback@apinchofhealth.com]
www.tinyurl.com/3au3a5 [LoveDiabetes.com]
www.tinyurl.com/2v9ajm [http://www.lovediabetes.com/]
www.tinyurl.com/yrr5kd [LoveDiabetes.com]
> 1207 www.tinyurl.com/2vp4e9 [DrBernarr@aol.com]
> http://www.healself.org/ [DrBernarr@aol.com]

Eating less OFTEN can CURE any diabetes ?

Nick Gracey WATerian BSc(Hons) Medical BioChemistry, Birmingham University, Adrenaline LIFE2345.©OM

HOW(?) & WHY(?) Liquid-Eating & Intermittent-Fasting can be so beneficial to your Health...

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Nick Gracey WATerian BSc(Hons) Medical BioChemistry, Birmingham University, Adrenaline LIFE2345.©OM

HOW(?) & WHY(?) Liquid-Eating & Intermittent-Fasting can be so beneficial to your Health...

Wednesday 7 November 2007

WATerian ... REFERENCES...

1 comment:

Adrenalin Love ...

Sponsorship support ...

WATerian Health Farm

WiThin1.com

Introducing Intermittent Fasting ...

ADRENALINES

Please Subscribe NOW

WATerian Twitter

WATerian Twitter

Adrenaline Search

WATerian Blog List

Adrenalin Sub

About NDG

Adrenalin Love

WATerian ...

Subscribe via email

The WATerian CURE 4 fuel-anemia ...

CURE for T1 & T2 diabetes ...

Facebook

WATerian Nick Gracey BSc(Hons) Medical BioChemistry, Birmingham University, Adrenaline LIFE2345.©OM

The Gracey HYPO=thesis ...

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